Base 2 and base 16 are heavily used in computers, but base ten (decimal) is so heavily entrenched that the only other example I can think of where another base is commonly used is in old-style counting: dozen = 12, gross = 144 = 12*12, great gross = 1768 = 12*12*12.
Base four works the same way but we only have four symbols (0,1,2,3) for counting and each place is four times greater than the one to its right.
Hoping to dramatically increase their share, Sega set about creating a new machine that would be at least as powerful as the then most impressive hardware on the market - the 16-bit Commodore Amiga and the Atari ST home computers.
In an attempt to build themselves a significant consumer base, Sega decided to focus on slightly older buyers, especially young men in their late teens and early 20s who would have more disposable income and who were anxious for more "grown-up" titles with more mature content and/or more in-depth game play.
By 1994, Sega's market share had dropped from 65% to 35%, and the official announcements of newer, more powerful consoles, such as the Saturn, Playstation, and N64 signaled that the 16-bit era was drawing to a close.