 | | Prednisolone | | Systematic (IUPAC) name | | 11,17-dihydroxy-17- (2-hydroxyacetyl)- 10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17- dodecahydrocyclopenta [a]phenanthren-3-one | | Identifiers | | CAS number | 50-24-8 | | ATC code | A07EA01 C05AA04, D07AA03, D07XA02, H02AB06, R01AD02, S01BA04, S01CB02, S02BA03, S03BA02 | | PubChem | 5755 | | DrugBank | APRD00197 | | Chemical data | | Formula | C21H28O5 | | Mol. mass | 360.444 g/mol | | Pharmacokinetic data | | Bioavailability | ? | | Metabolism | ? | | Half life | 2-3 hours | | Excretion | ? | | Therapeutic considerations | | Pregnancy cat. | ? Image File history File links Download high-resolution version (1100x649, 38 KB) File links The following pages on the English Wikipedia link to this file (pages on other projects are not listed): Prednisolone ...
IUPAC nomenclature is a system of naming chemical compounds and of describing the science of chemistry in general. ...
CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences, mixtures and alloys. ...
The Anatomical Therapeutic Chemical Classification System is used for the classification of drugs. ...
A division of the Anatomical Therapeutic Chemical Classification System A Alimentary tract and metabolism A07A Intestinal anti-infectives A07AA Antibiotics A07AA01 Neomycin A07AA02 Nystatin A07AA03 Natamycin A07AA04 Streptomycin A07AA05 Polymyxin B A07AA06 Paromomycin A07AA07 Amphotericin B A07AA08 Kanamycin A07AA09 Vancomycin A07AA10 Colistin A07AA11 Rifaximin A07AA51 Neomycin, combinations A07AA54 Streptomycin, combinations...
A section of the Anatomical Therapeutic Chemical Classification System. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
PubChem is a database of chemical molecules. ...
The DrugBank database available at the University of Alberta is a unique bioinformatics and cheminformatics resource that combines detailed drug (i. ...
A chemical formula (also called molecular formula) is a concise way of expressing information about the atoms that constitute a particular chemical compound. ...
General Name, Symbol, Number carbon, C, 6 Chemical series nonmetals Group, Period, Block 14, 2, p Appearance black (graphite) colorless (diamond) Standard atomic weight 12. ...
General Name, Symbol, Number hydrogen, H, 1 Chemical series nonmetals Group, Period, Block 1, 1, s Appearance colorless Atomic mass 1. ...
General Name, Symbol, Number oxygen, O, 8 Chemical series nonmetals, chalcogens Group, Period, Block 16, 2, p Appearance colorless (gas) very pale blue (liquid) Standard atomic weight 15. ...
The molecular mass (abbreviated MM) of a substance, formerly also called molecular weight and abbreviated as MW, is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ...
In pharmacology, bioavailability is used to describe the fraction of an administered dose of medication that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs. ...
Drug metabolism is the metabolism of drugs, their biochemical modification or degradation, usually through specialized enzymatic systems. ...
It has been suggested that Effective half-life be merged into this article or section. ...
Excretion is the process of eliminating waste products of metabolism and other materials that are of no use. ...
The pregnancy category of a pharmaceutical agent is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. ...
| | Legal status | | | Routes | ? | Prednisolone is the active metabolite of prednisone. The regulation of therapeutic goods, that is drugs and therapeutic devices, varies by jurisdiction. ...
In pharmacology and toxicology, a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body 1. ...
This article or section does not adequately cite its references or sources. ...
Prednisolone has an extremely bitter taste that makes it difficult to administer to children. Bitter can refer to: Bitter, one of the five basic tastes; Bitter, a kind of ale particularly popular in Britain or Bitters, a herbal preparation now used mostly in cocktails. ...
Uses It is a corticosteroid drug with predominantly glucocorticoid and low mineralocorticoid activity, making it useful for the treatment of a wide range of inflammatory and auto-immune conditions such as asthma, rheumatoid arthritis, Ulcerative Colitis and Crohn's disease, multiple sclerosis, cluster headaches and Systemic Lupus Erythematosus. It can also be used as an immunosuppressive drug for organ transplants. Predisolone acetate opthamolic suspension is a sterile corticosteroid used to help to reduce swelling, redness, itching, and allergic reactions affecting the eye. In physiology, corticosteroids are a class of steroid hormones that are produced in the adrenal cortex. ...
Glucocorticoids are a class of steroid hormones characterised by an ability to bind with the cortisol receptor and trigger similar effects. ...
Mineralocorticoids is a class of steroids characterised by their similarity to aldosterone and their influence on salt and water metabolism. ...
Autoimmune diseases arise from an overactive immune response of the body against substances and tissues normally present in the body. ...
Rheumatoid arthritis (RA) is traditionally considered a chronic, inflammatory autoimmune disorder that causes the immune system to attack the joints. ...
Crohns disease (also known as regional enteritis) is a chronic, episodic, inflammatory condition of the gastrointestinal tract characterized by transmural inflammation (affecting the entire wall of the involved bowel) and skip lesions (areas of inflammation with areas of normal lining in between). ...
Cluster headaches are rare headaches that occur in groups or clusters. ...
Immunosuppression is the medical suppression of the immune system. ...
An organ transplant is the transplantation of an organ (or part of one) from one body to another, for the purpose of replacing the recipients damaged or failing organ with a working one from the donor. ...
Prescribed for treatment of Croup in toddlers.
Side effects Possible side effects include fluid retention of the face (moon face, Cushing's Syndrome), acne, constipation and mood swings. Ocular Side-effects if taken; Constipation or irregularity, is a condition of the digestive system where a person (or animal) experiences hard feces that are difficult to eliminate; it may be extremely painful, and in severe cases (fecal impaction) lead to symptoms of bowel obstruction. ...
A mood swing is an extreme change in mood. ...
Systemically: Posterior subcapsular cataracts & papilledema Papilledema is optic disc swelling that is caused by increased intracranial pressure. ...
Topical: PSC & glaucoma Contraindicated with herpes Contraindicated is a medical term to indicate a situation in which a medication or treatment should not be administered. ...
Genera Subfamily Alphaherpesvirinae Simplexvirus Varicellovirus Mardivirus Iltovirus Subfamily Betaherpesvirinae Cytomegalovirus Muromegalovirus Roseolovirus Subfamily Gammaherpesvirinae Lymphocryptovirus Rhadinovirus Unassigned Ictalurivirus The Herpesviridae are a family of DNA viruses that cause diseases in humans and animals. ...
Alclometasone, Aldosterone, Amcinonide, Beclometasone, Betamethasone, Budesonide, Ciclesonide, Clobetasol, Clobetasone, Clocortolone, Cloprednol, Cortisone, Cortivazol, Deflazacort, Deoxycorticosterone, Desonide, Desoximetasone, Desoxycortone, Dexamethasone, Diflorasone, Diflucortolone, Difluprednate, Fluclorolone, Fludrocortisone, Fludroxycortide, Flumetasone, Flunisolide, Fluocinolone acetonide, Fluocinonide, Fluocortin, Fluocortolone, Fluorometholone, Fluperolone, Fluprednidene, Fluticasone, Formocortal, Halcinonide, Halometasone, Hydrocortisone/cortisol, Hydrocortisone aceponate, Hydrocortisone buteprate, Hydrocortisone butyrate, Loteprednol, Medrysone, Meprednisone, Methylprednisolone, Methylprednisolone aceponate, Mometasone furoate, Paramethasone, Prednicarbate, Prednisone, Prednisolone, Prednylidene, Rimexolone, Tixocortol, Triamcinolone, Ulobetasol In physiology, corticosteroids are a class of steroid hormones that are produced in the adrenal cortex. ...
Glucocorticoids are a class of steroid hormones characterised by an ability to bind with the cortisol receptor and trigger similar effects. ...
The âââglucocorticoid receptorâââ (GR) is a ligand-activated intracytoplasmatic transcription factor that interacts with high affinity to cortisol and other glucocorticoids. ...
Mineralocorticoids is a class of steroids characterised by their similarity to aldosterone and their influence on salt and water metabolism. ...
The mineralocorticoid receptor (MR, MLR, MCR), also aldosterone receptor, is officially labelled nuclear receptor subfamily 3, group C, member 2, (NR3C2) and is a receptor with high affinity for mineralocorticoids. ...
A division of the Anatomical Therapeutic Chemical Classification System A Alimentary tract and metabolism A07A Intestinal anti-infectives A07AA Antibiotics A07AA01 Neomycin A07AA02 Nystatin A07AA03 Natamycin A07AA04 Streptomycin A07AA05 Polymyxin B A07AA06 Paromomycin A07AA07 Amphotericin B A07AA08 Kanamycin A07AA09 Vancomycin A07AA10 Colistin A07AA11 Rifaximin A07AA51 Neomycin, combinations A07AA54 Streptomycin, combinations...
A section of the Anatomical Therapeutic Chemical Classification System. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
Alclometasone is a synthetic glucocorticoid steroid, available in cream or ointment form, for topical dermatologic use. ...
Aldosterone is a steroid hormone synthesized from cholesterol by the enzyme aldosterone synthase. ...
Amcinonide is a corticosteroid. ...
Beclometasone dipropionate (INN, Beclomethasone dipropionate (BAN) is a corticosteroid drug. ...
Betamethasone dipropionate is a corticosteroid with anti-inflammatory and immunosuppressive abilities, used especially where water retention is undesirable. ...
Budesonide is a corticosteroid for the treatment of asthma, non-infectious rhinitis (including hay fever and other allergies), and for treatment and prevention of nasal polyposis. ...
Ciclesonide is a glucocorticoid used to treat obstructive airway diseases. ...
Clobetasol Propionate comes in ointment and emollient cream presentations. ...
Clobetasone is a corticosteroid used in dermatology and ophthalmology. ...
Clocortolone (or clocortolone pivalate) is a corticosteroid. ...
Cloprednol is a glucocorticoid. ...
Cortisone (IPA:ËkôrtÉËsÅn) is a steroid hormone. ...
Cortivazol is a glucocorticoid. ...
Deflazacort is a glucocorticoid. ...
Deoxycorticosterone Deoxycorticosterone is a steroid hormone produced by the adrenal gland that posses mineralocorticoid activity and acts as a precursor to aldosterone. ...
Desonide is an anti-inflammatory corticosteroid typically used topically. ...
Topicort is a medication belonging to the family of medications known as topical corticosteroids. ...
Desoxycorticosterone (11-deoxycorticosterone) is a mineralocorticoid. ...
Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid hormones. ...
Diflorasone is a corticosteroid. ...
Diflucortolone is a corticosteroid. ...
Difluprednate is a corticosteroid. ...
Fluclorolone is a corticosteroid. ...
Fludrocortisone acetate is a synthetic corticosteroid with moderate glucocorticoid potency and much greater mineralocorticoid potency. ...
Floudroxycortide (or Flurandrenolone or Flurandrenolide ) is a synthetic steriod and is used as an anti-inflammatory treatment for use on skin irritations. ...
Flumethasone (or flumetasone) is a corticosteroid. ...
Flunisolide is a corticosteroid often prescribed as treatment for allergic rhinitis. ...
Fluocinolone acetonide is a corticosteroid primarily used in dermatology. ...
To meet Wikipedias quality standards, this article or section may require cleanup. ...
Fluocortin is a corticosteroid. ...
Fluocortolone is a glucocorticoid used in the treatment of several conditions, including hemorrhoids. ...
Fluorometholone is a corticosteroid, most often used after Laser Eye Surgery. ...
Fluperolone acetate is a corticosteroid. ...
Fluprednidene acetate is a corticosteroid. ...
Fluticasone proprionate is a glucocorticoid often prescribed as treatment for asthma and allergic rhinitis. ...
Formocortal is a corticosteroid used in ophthalmology. ...
Halcinonide is a corticosteroid. ...
Halometasone is a corticosteroid. ...
Cortisol is a corticosteroid hormone produced by the adrenal cortex that is involved in the response to stress; it increases blood pressure, blood sugar levels, may cause infertility in women, and suppresses the immune system. ...
Hydrocortisone aceponate is a corticosteroid. ...
Hydrocortisone buteprate (or hydrocortisone 17-butyrate 21-propionate) is a corticosteroid. ...
Steroid skeleton. ...
Loteprednol (or loteprednol etabonate) is a corticosteroid used in ophthalmology. ...
Medrysone is a corticosteroid used in ophthalmology. ...
Meprednisone is a glucocorticoid. ...
Methylprednisolone (molecular weight 374. ...
Methylprednisolone aceponate is a corticosteroid. ...
Mometasone furoate (also referred to as Mometasone) is a moderately potent glucocorticoid steroid used in the treatment of inflammatory skin disorders (such as eczema and psoriasis), allergic rhinitis (such as hayfever), and asthma for patients unresponsive to less potent corticosteroids. ...
Paramethasone is a fluorinated glucocorticoid used as an anti-inflammatory. ...
Prednicarbate is a corticosteroid. ...
This article or section does not adequately cite its references or sources. ...
Prednylidene is a glucocorticoid for systemic use. ...
Rimexolone (Vexol®) is a corticosteroid, often used in eye drops to treat inflammation in the eye. ...
Tixocortol is a corticosteroid used as a intestinal anti-inflammatory and decongestant. ...
Triamcinolone (trade names Kenalog®, Aristocort®, Nasacort®, Tri-Nasal®, Triderm®, Azmacort®, Fougera®) is a synthetic corticosteroid given orally, by injection, inhalation, or as a topical cream. ...
Ulobetasol (or halobetasol) is a corticosteroid. ...
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