A premalignant condition is a disease, syndrome, or finding that, if left untreated, may lead to cancer. A disease is an abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person afflicted or those in contact with the person. ... In medicine, the term syndrome is the association of several clinically recognizable features, signs, symptoms, phenomena or characteristics which often occur together, so that the presence of one feature alerts the physician to the presence of the others. ... When normal cells are damaged beyond repair, they are eliminated by apoptosis. ...
Examples of pre-malignant conditions include actinic keratosis and Barrett's esophagus. Actinic keratosis also called solar keratosis, senile keratosis, or AK, is a premalignant condition of thick, scaly, or crusty patches of skin. ... Barretts esophagus refers to an abnormal change (metaplasia) in the cells of the lower end of the esophagus thought to be caused by damage from chronic acid exposure, or reflux esophagitis. ...