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Encyclopedia > Priapism
Priapism
Classification and external resources
ICD-10 N48.3
ICD-9 607.3
DiseasesDB 25148
eMedicine med/1908 
MeSH D011317

Priapism (Ancient Greek: πριαπισμός) is a potentially harmful medical condition in which the erect penis does not return to its flaccid state (despite the absence of both physical and psychological stimulation) within about four hours. It is often painful. Priapism is considered a medical emergency, which should receive proper treatment by a qualified medical practitioner. The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ... The International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10) is a coding of diseases and signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or diseases, as classified by the World Health Organization (WHO). ... // N00-N39 - Diseases of the genitourinary system: urinary system (N00-N08) Glomerular diseases Prefixes: .2 Diffuse membranous glomerulonephritis (N00) Acute nephritic syndrome (N01) Rapidly progressive nephritic syndrome (N02) Recurrent and persistent haematuria (N03) Chronic nephritic syndrome (N04) Nephrotic syndrome Lipoid nephrosis (N05) Unspecified nephritic syndrome (N06) Isolated proteinuria with specified... The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ... The following is a list of codes for International Statistical Classification of Diseases and Related Health Problems. ... The Disease Bold textDatabase is a free website that provides information about the relationships between medical conditions, symptoms, and medications. ... eMedicine is an online clinical medical knowledge base that was founded in 1996. ... Medical Subject Headings (MeSH) is a huge controlled vocabulary (or metadata system) for the purpose of indexing journal articles and books in the life sciences. ... Beginning of Homers Odyssey The Ancient Greek language is the historical stage of the Greek language[1] as it existed during the Archaic (9th–6th centuries BC) and Classical (5th–4th centuries BC) periods in Ancient Greece. ... This article is about human physiological erection. ... The penis (plural penises, penes) is an external male sexual organ. ... {{Otheruses4|the medical term|the Australian television series|Medical Emergenc an immediate threat to a persons life or long term health. ...


The name comes from the Greek god Priapus, referring to the myth that he was ironically punished by the other gods for attempting to rape a goddess, by being given a huge (but useless) set of wooden genitals. Fresco of Priapus, House of the Vettii, Pompeii. ...

Contents

Causes

Wall painting with Priapus, Casa Dei Vettii, Pompei

The causative mechanisms are poorly understood but involve complex neurological and vascular factors. Priapism may be associated with haematological disorders, especially sickle-cell disease, and other conditions such as leukemia, thalassemia, and Fabry's disease, and neurologic disorders such as spinal cord lesions and spinal cord trauma (priapism has been reported in hanging victims; see death erection). Recent breakthrough in the research of the disease have pointed to a raised level of the biochemical adenosine being the cause of the condition. This seems to cause blood vessels to dilate and has the potential to influence blood flow into the penis.[1] Fresco of Priapus, House of the Vettii, Pompeii. ... Vascular is an adjective for the word vessel and refers to tube-like structures. ... Hematology (American English) or haematology (British English) is the branch of biology (physiology), pathology, clinical laboratory, internal medicine, and pediatrics that is concerned with the study of blood, the blood-forming organs, and blood diseases. ... sickle cell redirects here. ... Leukemia or leukaemia (Greek leukos λευκός, white; aima αίμα, blood) is a cancer of the blood or bone marrow and is characterized by an abnormal proliferation (production by multiplication) of blood cells, usually white blood cells (leukocytes). ... Thalassemia (British spelling, thalassaemia) is an inherited autosomal recessive blood disease. ... Fabry disease (also known as Anderson-Fabry disease, Angiokeratoma corporis diffusum, Ceramide trihexosidosis, and Sweeley-Klionsky disease) is an X-linked recessive inherited lysosomal storage disease. ... Neurology is a branch of medicine dealing with disorders of the nervous system. ... The Spinal cord nested in the vertebral column. ... A death erection or terminal erection[1] is a post-mortem erection, technically a priapism, observed in the corpses of human males who have been executed, particularly by hanging. ...


Priapism can be caused by medications. The most common medications that cause priapism are intra-cavernous injections for treatment of erectile dysfunction (papaverine, alprostadil). Other groups reported are antihypertensives, antipsychotics (e.g chlorpromazine, clozapine), antidepressants (most notably trazodone), anticoagulants, cantharides (Spanish Fly) and recreational drugs (alcohol and cocaine). Phosphodiesterase type-5 (PDE5) inhibitors such as sildenafil (popularly Viagra), tadalafil and vardenafil have very rarely been implicated, and probably do not cause priapism. PDE-5 inhibitors have even been evaluated as preventive treatment for recurrent priapism.[2][3] This article does not cite any references or sources. ... Erectile dysfunction (ED) or impotence is a sexual dysfunction characterized by the inability to develop or maintain an erection of the penis. ... Papaverine is an opium alkaloid used primarily in the treatment of visceral spasm, vasospasm (especially those involving the heart and the brain), and occasionally in the treatment of erectile dysfunction. ... Alprostadil is a prostaglandin analogue used as a drug in the treatment of erectile dysfunction and has vasodilatory properties. ... In medicine and pharmacology, antihypertensives are a class of drugs that are used in the treatment of arterial hypertension. ... The term antipsychotic is applied to a group of drugs used to treat psychosis. ... Chlorpromazine was the first antipsychotic drug, used during the 1950s and 1960s. ... Clozapine (sold as Clozaril®, Leponex®, Fazaclo®) was the first of the atypical antipsychotics to be developed. ... Prozac, a selective serotonin reuptake inhibitor (SSRI) Serotonin-norepinephrine reuptake inhibitor, Venlafaxine An antidepressant is a psychiatric medication or other substance (nutrient or herb) used for alleviating depression or dysthymia (milder depression). ... Trazodone (trade names Desyrel, Molipaxin, Trittico, Thombran, Trialodine) is a psychoactive compound with sedative, anxiolytic, and antidepressant properties. ... An anticoagulant is a substance that prevents coagulation; that is, it stops blood from clotting. ... Genera Chauliognathus Silis Cantharis Podabrus Malthodes and more The soldier beetles, or Cantharidae are relatively soft-bodied, straight sided beetles, closely related to the Lampyridae or firefly family. ... This article does not cite any references or sources. ... For other uses, see Cocaine (disambiguation). ... A phosphodiesterase type 5 inhibitor, often shortened to PDE5 inhibitor, is a drug used to block the degradative action of phosphodiesterase type 5 on cyclic GMP in the smooth muscle cells lining the blood vessels supplying the corpus cavernosum of the penis. ... Sildenafil citrate, sold under the names Viagra, Revatio and generically under various other names, is a drug used to treat male erectile dysfunction (impotence) and pulmonary arterial hypertension (PAH), developed by the pharmaceutical company Pfizer. ... // ... Tadalafil is an orally administered drug used to treat male erectile dysfunction (impotence). ... Vardenafil (INN) is a PDE5 inhibitor used in the treatment of erectile dysfunction. ...


Complications

Potential complications include ischemia, clotting of the blood retained in the penis (thrombosis), and damage to the blood vessels of the penis which may result in an impaired erectile function or impotence. In serious cases, the ischemia may result in gangrene, which could necessitate penis removal. In medicine, ischemia (Greek ισχαιμία, isch- is restriction, hema or haema is blood) is a restriction in blood supply, generally due to factors in the blood vessels, with resultant damage or dysfunction of tissue. ... Thrombosis is the formation of a clot or thrombus inside a blood vessel, obstructing the flow of blood through the circulatory system. ... Erectile dysfunction (ED) or impotence is a sexual dysfunction characterized by the inability to develop or maintain an erection of the penis. ... Gangrene is a complication of necrosis (i. ... Penectomy is the surgical removal of the penis for medical reasons. ...


Treatment

Medical advice should be sought immediately for cases of erection beyond four hours. Generally, this is done at an emergency department. The therapy at this stage is to aspirate blood from the corpus cavernosum under local anaesthetic. If this is still insufficient, then intra-cavernosal injections of phenylephrine are administered. This should only be performed by a trained urologist, with the patient under constant hemodynamic monitoring, as phenylephrine can cause severe hypertension, bradycardia, tachycardia, and arrhythmia. The emergency department (ED), sometimes termed the emergency room (ER), emergency ward (EW), accident & emergency (A&E) department or casualty department is a hospital or primary care department that provides initial treatment to patients with a broad spectrum of illnesses and injuries, some of which may be life-threatening and... A corpus cavernosum is one of a pair of a sponge-like regions of erectile tissue which contain most of the blood in the male penis during erection. ... Anesthesia (AE), also anaesthesia (BE), is the process of blocking the perception of pain and other sensations. ... Phenylephrine or Neo-Synephrine is an α-adrenergic receptor agonist used primarily as a decongestant, as an agent to dilate the pupil and to increase blood pressure. ... Hemodynamics (literally, blood dynamics), or hemorheology, is the study of the properties and flow of blood. ... Phenylephrine or Neo-Synephrine is an α-adrenergic receptor agonist used primarily as a decongestant, as an agent to dilate the pupil and to increase blood pressure. ... For other forms of hypertension, see Hypertension (disambiguation). ... Bradycardia, as applied to adult medicine, is defined as a resting heart rate of under 60 beats per minute, though it is seldom symptomatic until the rate drops below 50 beat/min. ... This article or section does not cite any references or sources. ... A cardiac arrhythmia, also called cardiac dysrhythmia, is a disturbance in the regular rhythm of the heartbeat. ...


If aspiration fails and tumescence recurs, surgical shunts are next attempted. These attempt to reverse the priapic state by shunting blood from the rigid corpora cavernosa into the corpus spongiosum (which contains the glans and the urethra). Distal shunts are the first step, followed by more proximal shunts. Tumescence is the quality or state of being tumescent or swollen. ... In medicine, a shunt is a device designed to drain excess cerebrospinal fluid from the brain and carry it to other parts of the body. ... Corpus spongiosum (Plural: Corpora Spongiosa) is the mass of spongy tissue surrounding the male urethra within the penis. ... The glans penis (or simply glans) is the sensitive tip of the penis. ... In anatomy, the urethra (from Greek ουρήθρα - ourethra) is a tube which connects the urinary bladder to the outside of the body. ...


Distal shunts, such as the Winter's, involves puncturing the glans (the distal part of the penis) into one of the cavernosa, where the old, stagnant blood is held. This causes the blood to leave the penis and return to the circulation. This procedure can be performed by a urologist at the bedside.


Proximal shunts, such as the Quackel's, are more involved and entail operative dissection in the perineum to where the corpora meet the spongiosum, making an incision in both, and suturing both openings together.[4] In human anatomy, the perineum, also called the taint, or gooch, is generally defined as the surface region in both males and females between the pubic symphysis and the coccyx. ...


Female Priapism

Female Priapism is better known as Clitorism. Clitorism (klitor-Izm), from the Greek kleitoris + ismos, is the female counterpart of priapism. ...


See also

Clitorism (klitor-Izm), from the Greek kleitoris + ismos, is the female counterpart of priapism. ...

References

  1. ^ Michael Day, Relief in sight for sufferers of constant erections. http://www.newscientist.com/channel/health/dn13461-relief-in-sight-for-sufferers-of-constant-erections.html?feedId=online-news_rss20
  2. ^ Burnett AL, Bivalacqua TJ, Champion HC, Musicki B (2006). "Long-term oral phosphodiesterase 5 inhibitor therapy alleviates recurrent priapism". Urology 67 (5): 1043-8. doi:10.1016/j.urology.2005.11.045. PMID 16698365. 
  3. ^ Burnett AL, Bivalacqua TJ, Champion HC, Musicki B (2006). "Feasibility of the use of phosphodiesterase type 5 inhibitors in a pharmacologic prevention program for recurrent priapism". The journal of sexual medicine 3 (6): 1077-84. doi:10.1111/j.1743-6109.2006.00333.x. PMID 17100941. 
  4. ^ Montague DK, Jarow J, Broderick GA, et al (2003). "American Urological Association guideline on the management of priapism". J. Urol. 170 (4 Pt 1): 1318-24. doi:10.1097/01.ju.0000087608.07371.ca. PMID 14501756. 
  • Beers MH, Berkow R (Eds.) (1999). The Merck Manual of Diagnosis and Therapy (17 ed.). Whitehouse Station: Merck Research Laboratories. ISBN 0-911910-10-7
  • Therapeutic Guidelines Limited (2001). Therapeutic Guidelines: Endocrinology (2 ed.). North Melbourne: Therapeutic Guidelines Limited. ISSN 1327-9505
  • Guidelines on management of priapism - American Urological Association website
  • Priapism Primer: Priapism
Hematospermia, or the presence of blood in semen, is most often a benign and idiopathic symptom, but can sometimes result from medical problems such as a urethral stricture, infection of the prostate, or a congenital bleeding disorder, and can occur transiently after surgical procedures such as a prostate biopsy. ... In males, retrograde ejaculation occurs when the fluid to be ejaculated, which would normally exit via the urethra, is redirected towards the urinary bladder. ... For other uses, see Breast (disambiguation). ... Chronic cystic mastitis, also called fibrocystic disease, Diffuse cystic mastopathy and Mammary dysplasia is a condition rather than a disease. ... Mastitis is the inflammation of the mammalian breast caused by the blocking of the milk ducts while the mother is lactating (see breastfeeding). ... Gynecomastia, or gynaecomastia, pronounced is the development of abnormally large mammary glands in males resulting in breast enlargement, which can sometimes cause secretion of milk. ... Galactorrhea or galactorrhoea is the spontaneous flow of milk from the breast, unassociated with childbirth or nursing. ... Mastalgia, mastodynia or mammalgia are names for a medical symptom that means - pain in the breast (from the Greek masto-, breast and algos, pain). ... Nipple discharge is the abnormal release of fluid from the nipples of the breasts. ... galactocele ...

  Results from FactBites:
 
Priapism - Wikipedia, the free encyclopedia (549 words)
Priapism (Greek πριαπισμός, the erection) is a painful and potentially harmful medical condition in which the erect penis (erection) does not return to its flaccid state (despite the absence of both physical and psychological stimulation) within four hours.
Priapism may be associated with prolonged sexual activity, leukaemia, Fabry's disease, haematological disorders (such as sickle-cell disease), cerebrospinal disease (such as syphilis), genital infection, some spinal injuries, or inflammation (Beers and Berkow, 1999).
Priapism is often present in spinal injuries or trauma to the spinal cord.
Priapism (1621 words)
Priapism is the occurrence of any persistent erection for more than four hours duration in the absence of sexual stimulation.
Priapism is named after Priapus, the Greek god of fertility, and the son of Aphrodite, the goddess of love.
Once priapism and its source have been identified, it is categorized into two major types: low-flow priapism or ischemic, which means that little or no blood flow is getting to the penis and this lack can cause damage; or high-flow priapism, which is the result of trauma to the penis.
  More results at FactBites »


 

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