 | | Prilocaine | | Systematic (IUPAC) name | | N-(2-methylphenyl)-2-propylamino-propanamide | | Identifiers | | CAS number | 721-50-6 | | ATC code | N01BB04 | | PubChem | 4906 | | DrugBank | APRD00180 | | Chemical data | | Formula | C13H20N2O | | Mol. mass | 220.311 g/mol | | Pharmacokinetic data | | Bioavailability | ? | | Protein binding | 55% | | Metabolism | Hepatic and renal | | Half life | 10-150 minutes, longer with impaired hepatic or renal function | | Excretion | ? | | Therapeutic considerations | | Pregnancy cat. | B (U.S.) Image File history File links No higher resolution available. ...
IUPAC nomenclature is a system of naming chemical compounds and of describing the science of chemistry in general. ...
CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences, mixtures and alloys. ...
The Anatomical Therapeutic Chemical Classification System is used for the classification of drugs. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
PubChem is a database of chemical molecules. ...
The DrugBank database available at the University of Alberta is a unique bioinformatics and cheminformatics resource that combines detailed drug (i. ...
A chemical formula is a concise way of expressing information about the atoms that constitute a particular chemical compound. ...
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General Name, Symbol, Number hydrogen, H, 1 Chemical series nonmetals Group, Period, Block 1, 1, s Appearance colorless Atomic mass 1. ...
General Name, symbol, number nitrogen, N, 7 Chemical series nonmetals Group, period, block 15, 2, p Appearance colorless gas Standard atomic weight 14. ...
General Name, symbol, number oxygen, O, 8 Chemical series nonmetals, chalcogens Group, period, block 16, 2, p Appearance colorless (gas) very pale blue (liquid) Standard atomic weight 15. ...
The molecular mass (abbreviated Mr) of a substance, formerly also called molecular weight and abbreviated as MW, is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ...
In pharmacology, bioavailability is used to describe the fraction of an administered dose of unchanged drug that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs. ...
A drugs efficacy may be affected by the degree to which it binds to the proteins within blood plasma. ...
Drug metabolism is the metabolism of drugs, their biochemical modification or degradation, usually through specialized enzymatic systems. ...
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The kidneys are important excretory organs in vertebrates. ...
The pregnancy category of a pharmaceutical agent is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. ...
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| | Legal status | | | Routes | ? | Prilocaine (IPA: [ˈpraɪlokeɪn]) is a local anesthetic of the amino amide type. In its injectable form (trade name Citanest), it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA). As it has low cardiac toxicity, it is commoly used for intravenous regional anaesthesia (IVRA). The regulation of therapeutic goods, that is drugs and therapeutic devices, varies by jurisdiction. ...
In pharmacology and toxicology, a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body 1. ...
Articles with similar titles include the NATO phonetic alphabet, which has also informally been called the âInternational Phonetic Alphabetâ. For information on how to read IPA transcriptions of English words, see IPA chart for English. ...
A local anesthetic is a drug that reversibly inhibits the propagation of signals along nerves. ...
In chemistry, especially in organic chemistry and biochemistry, an amino group is an ammonia-like functional group. ...
Amide functional group Amides possess a conjugated system spread over the O, C and N atoms, consisting of molecular orbitals occupied by delocalized electrons. ...
In pharmacology and toxicology, a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body 1. ...
A Dentist and Dental Assistant perform surgery on a patient. ...
Lidocaine/prilocaine is a eutectic mixture of equal quantities (by weight) of lidocaine and prilocaine. ...
In some patients, a metabolite of prilocaine may cause the unusual side-effect of methaemoglobinaemia. Maximum dosage for dental use: 6.0mg/kg (2.7mg/lb), with a maximum dose of 400mg. | Anesthetics: Local anesthetics (N01B) | | Esters of aminobenzoic acid | Procaine, Tetracaine, Chloroprocaine, Benzocaine | | Amides | Bupivacaine, Lidocaine, Mepivacaine, Prilocaine, Cinchocaine, Etidocaine, Articaine, Ropivacaine, Levobupivacaine | | Esters of benzoic acid | Cocaine | | Other | Hexylcaine, Iontocaine, Lidocaine/prilocaine | |