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Pringsheim was among the very first to demonstrate the occurrence of a sexual process in this class of plants, and he drew from his observations weighty conclusions as to the nature of sexuality.
This was a discovery of fundamental importance; the conjugation of zoospores was regarded by Pringsheim, with good reason, as the primitive form of sexual reproduction.
Closely connected with Pringsheims algological work was his long-continued investigation of the Saprolegniaceae, a family of algoid fungi, some of which have become notorious as the causes of disease in fish.
A new way to examine this issue, she added, is to look at a population of genetic males who take antiandrogens and estrogen to induce female sex characteristics.
Pringsheim, at the University of Toronto, and Dr. Louis Gooren, at Free University Amsterdam, distributed questionnaires regarding headache symptoms and frequency to 50 transsexuals who had recently undergone sex reassignment surgery, all of whom were taking hormonal therapy.
Pringsheim and Gooren theorize that the increased prevalence of migraine is related to the effect of hormone therapy on nitric oxide, a known migraine trigger.
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