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Encyclopedia > Protein in nutrition
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Proteins are broken down in the stomach during digestion by enzymes known as proteases into smaller polypeptides to provide amino acids for the organism, including the essential amino acids that the organism cannot biosynthesize itself. Aside from their role in protein synthesis, amino acids are also important nutritional sources of nitrogen. Image File history File links Portal. ... A representation of the 3D structure of myoglobin, showing coloured alpha helices. ... In anatomy, the stomach is a bean-shaped hollow muscular organ of the gastrointestinal tract involved in the second phase of digestion, following mastication. ... For the industrial process, see anaerobic digestion. ... Ribbon diagram of the enzyme TIM, surrounded by the space-filling model of the protein. ... Proteases (proteinases, peptidases, or proteolytic enzymes) are enzymes that break peptide bonds between amino acids of proteins. ... Peptides are the family of molecules formed from the linking, in a defined order, of various amino acids. ... In chemistry, an amino acid is any molecule that contains both amino and carboxylic acid functional groups. ... Domains and Kingdoms Nanobes Acytota Cytota Bacteria Neomura Archaea Eukaryota Bikonta Apusozoa Rhizaria Excavata Archaeplastida Rhodophyta Glaucophyta Plantae Heterokontophyta Haptophyta Cryptophyta Alveolata Unikonta Amoebozoa Opisthokonta Choanozoa Fungi Animalia An ericoid mycorrhizal fungus Life on Earth redirects here. ... An essential amino acid or indispensable amino acid is an amino acid that cannot be synthesized de novo by the organism (usually referring to humans), and therefore must be supplied in the diet. ... Biosynthesis is a phenomenon where chemical compounds are produced from simpler reagents. ... General Name, symbol, number nitrogen, N, 7 Chemical series nonmetals Group, period, block 15, 2, p Appearance colorless gas Standard atomic weight 14. ...


Proteins, like carbohydrates, contain 4 kilocalories per gram as opposed to lipids which contain 9 kilocalories and alcohols which contain 7 kilocalories. Proteins can be converted into carbohydrates through a process called gluconeogenesis. Carbohydrates (literally hydrates of carbon) are chemical compounds that act as the primary biological means of storing or consuming energy, other forms being fat and protein. ... A calorie is a unit of measurement for energy. ... Some common lipids. ... This article does not cite any references or sources. ... Pyruvic acid Oxaloacetic acid Phosphoenolpyruvate Fructose 1,6-bisphosphate Fructose 6-phosphate Glucose-6-phosphate Glucose Gluconeogenesis is the generation of glucose from non-sugar carbon substrates like pyruvate, lactate, glycerol, and amino acids (primarily alanine and glutamine). ...

Contents

Sources of proteins

Dietary sources of protein include meats, eggs, grains, legumes, and dairy products such as milk and cheese.[1] Of the 20 amino acids used by humans, the 10-12 nonessential amino acids can be synthesized by the body, and are not required in the diet. The 8-10 essential amino acids, however, cannot be created by the body and must come from dietary sources. This article is about the food. ... Chicken egg (left) and quail eggs (right), the types of egg commonly used as food An egg is a body consisting of an ovum surrounded by layers of membranes and an outer casing of some type, which acts to nourish and protect a developing embryo. ... The word grain has several meanings, most being descriptive of a small piece or particle. ... This article is about the fruit of the plants also called legumes. For the plants themselves, see Fabaceae . ... Dairy products are generally defined as foodstuffs produced from milk. ... A glass of cows milk. ... Cheese is a solid food made from the milk of cows, goats, sheep, and other mammals. ...


Most animal sources and certain vegetable sources have the complete complement of all 8-10 essential amino acids. However, it is not necessary to consume a single food source that contains all the essential amino acids, as long as all the essential amino acids are eventually present in the diet: see complete protein and protein combining. A complete protein or whole protein is a protein that contains all amino acids, most notably the nine essential amino acids to humans and most animals, in ratios appropriate to the body. ... Protein combining (also protein complementing) is the theory, now largely discredited (citation needed), that vegetarians must eat foods such as beans and rice together, or at least on the same day, so the different amino acids in the foods combine to form a complete protein, containing all eight essential amino...


Most animal sources of protein are classified as complete proteins because they contain all nine essential amino acids. Proteins found in plant foods, however, are called incomplete proteins because they are missing one or more essential amino acids. Eating multiple plant protein sources such as grains combined with legumes can adequately provide all essential amino acids. For example, bread and peanut butter, or rice and beans, provide all nine essential amino acids. {{cite book |author=Margen, Sheldon; Sheldon, Md Levine |title=The wellness encyclopedia of food and nutrition: how to buy, store, and prepare every fresh food |publisher=Rebus |location=New York |year=1992 |pages= |isbn=0-929661-03-6 |oclc= |doi=}pp.22,23} {{cite book |author=Sucher, Kathryn; Kittler, Pamela Goyan |title=Food and culture |publisher=Thomson Higher Education |location=Belmont, CA |year=2008 |pages= |isbn=0-495-11541-X |oclc= |doi=} pp. 212,213} Dietary Guidelines for Americans. Retrieved on 2008-03-11. 2008 (MMVIII) is the current year, a leap year that started on Tuesday of the Anno Domini (or common era), in accordance to the Gregorian calendar. ... is the 70th day of the year (71st in leap years) in the Gregorian calendar. ...


Protein quality

Different proteins have different levels of biological availability to the human body. Many methods have been introduced to measure protein utilization and retention rates in humans. They include biological value, Net Protein Utilization or NPU, and PDCAAS (Protein Digestibility Corrected Amino Acids Score) which was developed by the FDA as an improvement over the Protein Efficiency Ratio (PER) method. These methods examine which proteins are most efficiently used by the body. In general they conclude that animal complete proteins that contain all the essential amino acids such as milk, eggs, and meat, and the complete vegetable protein soy are of most value to the body[1]. Biological Value or BV is a common method for measuring protein quality and biological utilization rates of protein for human and animal consumption. ... NPU may mean: neighborhood planning unit National Power Unity Northwestern Polytechnic University, Fremont, California, USA This page concerning a three-letter acronym or abbreviation is a disambiguation page — a navigational aid which lists other pages that might otherwise share the same title. ... Protein Digestibility Corrected Amino Acid Score (PDCAAS) is a method of evaluating the protein quality based on the amino acid requirements of humans. ... Protein Efficiency Ratio (PER) is based on the weight gain of a test subject divided by its intake of a particular food protein during the test period. ...


Egg whites have been determined to have the highest biological value of 100, which means that all of the absorbed nitrogen from egg white protein can be retained and used by the body. Since the amino acids found in plants are biologically different from those found in humans and animals, the biological value of plant protein sources is considerably lower. For example, corn has a BA of 70 while peanuts have a relatively low BA of 40. {{cite book |author=Wardlaw, Gordon M. |title=Perspectives in Nutrition |publisher=McGraw-Hill Higher Education |location=Boston |year= |pages= |isbn=0-07-282750-5 |oclc= |doi=}pp. 259,260}


Digestion of protein

Digestion typically begins in the stomach when pepsinogen is converted to pepsin by the action of hydrochloric acid, and continued by trypsin and chymotrypsin in the intestine. The amino acids and their derivatives into which dietary protein is degraded are then absorbed by the gastrointestinal tract. The absorption rates of individual amino acids are highly dependent on the protein source; for example, the digestibilities of many amino acids in humans differ between soy and milk proteins[2] and between individual milk proteins, beta-lactoglobulin and casein.[3] For milk proteins, about 50% of the ingested protein is absorbed between the stomach and the jejunum and 90% is absorbed by the time the digested food reaches the ileum.[4] Biological value (BV) is a measure of the proportion of absorbed protein from a food which becomes incorporated into the proteins of the organism's body. In anatomy, the stomach is a bean-shaped hollow muscular organ of the gastrointestinal tract involved in the second phase of digestion, following mastication. ... Pepsin is a protease, a digestive enzyme that degrades food proteins in the stomach; the other important digestive enzymes are trypsin and chymotrypsin. ... Pepsin is a digestive protease (EC 3. ... Hydrochloric acid is the aqueous solution of hydrogen chloride gas (HCl). ... Trypsin (EC 3. ... Chymotrypsin (bovine γ chymotrypsin: PDB 1AB9, EC 3. ... Gut redirects here. ... Binomial name Glycine max Soybeans (US) or soya beans (UK) (Glycine max) are a high-protein legume (Family Fabaceae) grown as food for both humans and livestock. ... A glass of cows milk. ... The structure of β-lactoglobulin from PDB entry 3BLG The ribbons denote the secondary structure. ... Casein (from Latin caseus cheese) is the most predominant phosphoprotein found in milk and cheese. ... In anatomy, the stomach is a bean-shaped hollow muscular organ of the gastrointestinal tract involved in the second phase of digestion, following mastication. ... Diagram of the Human Intestine In anatomy of the digestive system, the jejunum is the central of the three divisions of the small intestine and lies between the duodenum and the ileum. ... Grays Fig. ... Biological Value or BV is a common method for measuring protein quality and biological utilization rates of protein for human and animal consumption. ... A representation of the 3D structure of myoglobin showing coloured alpha helices. ...


Dietary requirements

According to the recently updated Dietary Reference Intake guidelines, women aged 19–70 need to consume 46 grams of protein per day, while men aged 19–70 need to consume 56 grams of protein per day to avoid a deficiency. The difference is due to the fact that men's bodies generally have more muscle mass than those of women, or this may be attributed to weight difference by taking 0.8 g(of protein)/kg of body weight. The Dietary Reference Intake is a system of nutrition recommendations from the Institute of Medicine of the USA National Academy (IOM). ...


Because the body is continually breaking down protein from tissues, even adults who do not fall into the above categories need to include adequate protein in their diet every day. If enough energy is not taken in through diet, the body will use protein from the muscle mass to meet its energy needs, leading to muscle wasting over time.


Other recommendations suggest 0.8 gram of protein per kilogram of bodyweight per day while other sources suggest that higher intakes of 1-1.4 grams of protein per kilogram of bodyweight for enhanced athletes or those with a large muscle mass[citation needed]. [2].


How much protein needed in a person's daily diet is determined in large part by overall energy intake, as well as by the body's need for nitrogen and essential amino acids. Physical activity and exertion as well as enhanced muscular mass increase your need for protein. Requirements are also greater during childhood for growth and development, during pregnancy or when breast-feeding in order to nourish a baby, or when the body needs to recover from malnutrition or trauma or after an operation. An essential amino acid or indispensable amino acid is an amino acid that cannot be synthesized de novo by the organism (usually referring to humans), and therefore must be supplied in the diet. ...


Protein deficiency

Protein deficiency in developing countries

Many of the children in this photograph from a Nigerian orphanage in the late 1960s show symptoms of malnutrition, with four in particular illustrating the gray-blond hair symptomatic of kwashiorkor.

Protein deficiency is a serious cause of ill health and death in developing countries. Protein deficiency plays a part in the disease kwashiorkor. War, famine, overpopulation and other factors can increase rates of malnutrition and protein deficiency. Protein deficiency can lead to reduced intelligence or mental retardation, see deficiency in proteins, fats, carbohydrates. Image File history File linksMetadata Download high-resolution version (1642x1226, 565 KB) This photograph is public domain implicitly by being the work of a US Government agency, but the public domain status is also explicitly stated on the CDC website. ... Image File history File linksMetadata Download high-resolution version (1642x1226, 565 KB) This photograph is public domain implicitly by being the work of a US Government agency, but the public domain status is also explicitly stated on the CDC website. ... The Federal Republic of Nigeria is a country in West Africa and, by far, the most populated nation in Africa. ... // An orphanage is an institution or asylum for the care of a child bereaved of both father and mother; sometimes, also, a child who has but one parent living. ... Percentage of population affected by malnutrition by country, according to United Nations statistics. ...  High human development Medium human development Low human development Unavailable (colour-blind compliant map)   Developing countries not listed as least developed countries or as newly industrialized countries, in their respective articles. ... For other uses, see War (disambiguation). ... <nowiki>Insert non-formatted text hereBold text</nowiki>A famine is a social and economic crisis that is commonly accompanied by widespread malnutrition, starvation, epidemic and increased mortality. ... Map of countries by population density (See List of countries by population density. ... Percentage of population affected by malnutrition by country, according to United Nations statistics. ... For other uses, see Intelligence (disambiguation). ... Mental retardation is a term for a pattern of persistently slow learning of basic motor and language skills (milestones) during childhood, and a significantly below-normal global intellectual capacity as an adult. ... To meet Wikipedias quality standards, this article or section may require cleanup. ...


In countries that suffer from widespread protein deficiency, food is generally full of plant fibers, which makes adequate energy and protein consumption very difficult. Symptoms of kwashiorkor include apathy, diarrhea, inactivity, failure to grow, flaky skin, fatty liver, and edema of the belly and legs. This edema is explained by the normal functioning of proteins in fluid balance and lipoprotein transport. {{cite book |author=Jeffery Schwartz; Bryant, Carol A.; DeWalt, Kathleen Musante; Anita Courtney |title=The cultural feast: an introduction to food and society |publisher=Thomson/Wadsworth |location=Belmont, CA |year=2003 |pages= |isbn=0-534-52582-2 |oclc= |doi=}pp. 282,283} Apache Tomcat/6.0.14 - Error report. Retrieved on 2008-03-11. 2008 (MMVIII) is the current year, a leap year that started on Tuesday of the Anno Domini (or common era), in accordance to the Gregorian calendar. ... is the 70th day of the year (71st in leap years) in the Gregorian calendar. ...


Dr. Latham, director of the Program in International Nutrition at Cornell University claims that malnutrition is a frequent cause of death and disease in third world countries. Protein-energy malnutrition (PEM) affects 500 million people and kills 10 million annually. In severe cases white blood cell numbers decline and the ability of leukocytes to fight infection decreases. [3] Cornell redirects here. ... For other uses, see Death (disambiguation), Dead (disambiguation), or Death (band). ... This article is about the medical term. ... For the Jamaican reggae band, see Third World (band). ... Nigerian child with kwashiorkor Protein-energy malnutrition (PEM), also known as protein-calorie malnutrition, is a malnutrition and deficiency syndrome in organisms, especially humans caused by the inadequate intake of macronutrients through food in their diet. ... White Blood Cells redirects here. ...


Protein deficiency in developed countries

Protein deficiency is rare in developed countries but small numbers of people have difficulty getting sufficient protein due to poverty. Protein deficiency can also occur in developed countries in people who are dieting or crash dieting to lose weight, or in older adults, who may have a poor diet. Convalescent people recovering from surgery, trauma, or illness may become protein deficient if they do not increase their intake to support their increased needs. A deficiency can also occur if the protein a person eats is incomplete and fails to supply all the essential amino acids. World map indicating Human Development Index (as of 2004). ... A boy from an East Cipinang trash dump slum in Jakarta, Indonesia shows what he found. ... Measuring body weight on a scale Dieting is the practice of ingesting food in a regulated fashion to achieve a particular objective. ... For the band, see Crashdïet. ... Weight loss, in the context of medicine or health or physical fitness, is a reduction of the total body weight, due to a mean loss of fluid, body fat or adipose tissue and/or lean mass, namely bone mineral deposits, muscle, tendon and other connective tissue. ... Paul Kruger in his old age. ... Look up Convalescence in Wiktionary, the free dictionary. ... For other uses, see Person (disambiguation). ... This article is about the class of chemicals. ...


Excess protein consumption

Because the body is unable to store in the form of protein, excess consumed protein is broken down and converted into sugars or fatty acids. The liver removes nitrogen from the amino acids, so that they can be burned as fuel, and the nitrogen is incorporated into urea, the substance that is excreted by the kidneys. These organs can normally cope with any extra workload but if kidney disease occurs, a decrease in protein will often be prescribed.[5] See the article on the kidney for the anatomy and function of healthy kidneys and a list of diseases involving the kidney. ...


Many researchers think excessive intake of protein forces increased calcium excretion. If there is to be excessive intake of protein, it is thought that a regular intake of calcium would be able to stabilize, or even increase the uptake of calcium by the small intestine, which would be more beneficial in older women.[6]


Proteins are often progenitors in allergies and allergic reactions to certain foods. This is because the structure of each form of protein is slightly different; some may trigger a response from the immune system while others remain perfectly safe. Many people are allergic to casein, the protein in milk; gluten, the protein in wheat and other grains; the particular proteins found in peanuts; or those in shellfish or other seafoods. It is extremely unusual for the same person to adversely react to more than two different types of proteins, due to the diversity between protein or amino acid types.[citation needed]. Allergy is an abnormal reaction to a substance foreign to the body that is acquired, predictable and rapid. ... Pancreatitus can be caused by an Allergic Reaction to a food. ... Casein (from Latin caseus cheese) is the most predominant phosphoprotein found in milk and cheese. ... Wheat - a prime source of gluten Gluten is an amorphous mixture of ergastic (i. ... Binomial name L. This article is about the legume. ... Cooked mussels Shellfish is a term used to describe shelled molluscs and crustaceans used as food. ... Spaghetti with seafood (Spaghetti allo scoglio). ...


Testing for protein in foods

The classic assay for protein concentration in food is the Kjeldahl method. This test determines the total nitrogen in a sample. The only major component of most food which contains nitrogen is protein (fat, carbohydrate and dietary fibre do not contain nitrogen). If the amount of nitrogen is multiplied by a factor depending on the kinds of protein expected in the food the total protein can be determined. On food labels the protein is given by the nitrogen multiplied by 6.25, because the average nitrogen content of proteins is about 16%. The Kjeldahl test is used because it is the method the AOAC International has adopted and is therefore used by many food standards agencies around the world. An assay is a procedure where the concentration of a component part of a mixture is determined. ... The Kjeldahl method in analytical chemistry is a method for the quantitative determination of nitrogen in chemical substances developed by Johan Kjeldahl [1]. The method as described in Julius Cohens Practical Organic Chemistry of 1910 consists of heating a substance with sulfuric acid which decomposes the organic nitrogen present... AOAC International is a not-for-profit scientific association. ...


See also

Biological Value or BV is a common method for measuring protein quality and biological utilization rates of protein for human and animal consumption. ... An essential amino acid or indispensable amino acid is an amino acid that cannot be synthesized de novo by the organism (usually referring to humans), and therefore must be supplied in the diet. ...

References

  1. ^ USDA National Nutrient Database for Standard Reference, Release 20, United States Department of Agriculture. Last modified on September 26, 2007.
  2. ^ Gaudichon C, Bos C, Morens C, Petzke KJ, Mariotti F, Everwand J, Benamouzig R, Dare S, Tome D, Metges CC. (2002). Ileal losses of nitrogen and amino acids in humans and their importance to the assessment of amino acid requirements. Gastroenterology 123(1):50-9.
  3. ^ Mahe S, Roos N, Benamouzig R, Davin L, Luengo C, Gagnon L, Gausserges N, Rautureau J, Tome D. (1996). Gastrojejunal kinetics and the digestion of [15N]beta-lactoglobulin and casein in humans: the influence of the nature and quantity of the protein. Am J Clin Nutr 63(4):546-52.
  4. ^ Mahe S, Marteau P, Huneau JF, Thuillier F, Tome D. (1994). Intestinal nitrogen and electrolyte movements following fermented milk ingestion in man. Br J Nutr 71(2):169-80.
  5. ^ Born, Steve. Fueling For Endurance: Ten Mistakes Endurance Athletes Make and How You Can Avoid Them. UltraCycling Magazine.
  6. ^ Kerstetter, J. E., O'Brien, K. O., Caseria, D.M, Wall, D. E. & Insogna, K. L (2005) "The impact of dietary protein on calcium absorption and kinetic measures of bone turnover in women". J Clin Endocrinol Metab (2005) Vol 90, p26–31. PMID 15546911

Related Links


  Results from FactBites:
 
Protein in nutrition - Wikipedia, the free encyclopedia (1396 words)
Proteins are broken down by enzymes known as proteases into smaller polypeptides to provide amino acids for the organism, including the essential amino acids that the organism cannot biosynthesize itself.
Proteins are often progenitors in allergies and allergic reactions to certain foods.
For milk proteins, about 50% of the ingested protein is absorbed between the stomach and the jejunum and 90% is absorbed by the time the digested food reaches the ileum.
Nutrition (2213 words)
When a horse ingests protein, the chain of amino acids is broken up in the digestive tract by enzymes and acids, and the individual amino acids are absorbed through the wall of the small intestine and into the bloodstream via the liver.
The amount of crude protein needed in the diet depends on the needs of the individual horse (most importantly, is he still growing?), the digestibility of the protein, and the amount of the diet consumed.
Milk protein often is used as the primary protein source for foal feeds, but because it is quite expensive (and because adult horses are far less sensitive to protein quality differences), it's rarely found in feeds for mature animals.
  More results at FactBites »


 

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