Pteridine is a chemical compound composed of fused pyrimidine and pyrazine rings. A pteridine is also a group of heterocyclic compounds containing a wide variety of substitutions on this structure. Pterins and flavins are classes of substituted pteridines that have important biological activity. CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences and alloys. ... The molecular mass of a substance (less accurately called molecular weight and abbreviated as MW) is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ... Pyrimidine is a heterocyclic aromatic organic compound similar to benzene and pyridine, containing two nitrogen atoms at positions 1 and 3 of the six-member ring. ... Pyrazine is a symmetrical molecule. ... Heterocyclic compounds are substances which contain a ring structure as found in benzene and the aromatic compounds, or aromatic hydrocarbons, but in which other atoms than carbon, such as sulfur, oxygen or nitrogen are found as part of the ring. ... A pterin is any chemical compound that contains the bicyclic ring system of a pteridine. ... Riboflavin Flavin is a tricyclic heteronuclear organic ring based on pteridine whose biochemical source is the vitamin riboflavin. ...
A pterin is any chemical compound that contains the bicyclic ring system of a pteridine. ... Riboflavin Flavin is a tricyclic heteronuclear organic ring based on pteridine whose biochemical source is the vitamin riboflavin. ...
References
Voet, D.; Voet, J.G. (2004). Biochemistry (3rd ed.). John Wiley & Sons. ISBN 0-471-39223-5
Therefore, the present invention is based on the new recognition that in the case of retinopathia pigmentosa patients, the lack of pteridines, which appears to be of significance for the pathogenisis of this disease, can be compensated for by the administration of pteridines and/or by influencing the enzymes which destroy pteridines.
Therefore, the invention concerns the use of pteridines and/or biochemical precursors thereof or of an xanthinoxidase inhibitor for the treatment of genetically caused degnerative retina diseases.
Pteridines are found in nature and are isolated from the wings of butterflies and also from eyes of insects.