In response, the Mission was, as far as can be discerned from available sources, the first California mission to come under armed attack by local natives.
On the night of December 14, 1793, Mission Santa Cruz was attacked and partially burned by members of the local Quiroste tribe who inhabited the mountains to the east of Point Año Nuevo.
The attack was purportedly motivated by the forced relocation of native Indians to the Mission.
Nearly two years (1) of armed resistance on the part of members of the Quiroste tribe preceded the attack, which was probably the first extended resistance against the Spanish in the entire San Francisco Bay Area.The Quiroste tribe, an Ohlonean group, was situated around Año Nuevo and the mountains to the east.
Charquin was baptized at Mission San Francisco's outstation, San Pedro, on the eighteenth of November, at the age of sixty.
In December of 1793, after a raid on the Quirostes by Spanish soldiers recaptured fugitives from Mission Santa Cruz, the mission was attacked by the Quirostes.