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Encyclopedia > Regulatory T cells
This article or section should be merged with suppressor T cell

Regulatory T cells (also known as suppressor T cells) are characterised by virtue of their expression of the cell surface markers CD4 and CD25. They help to suppress or prevent autoimmunity by counteracting self-reactive lymphocytes. Some (but not all) do so by secreting inhibitory cytokines that block the activation of macrophages or other lymphocytes. It is unclear what factors cause immature T cells to develop into regulatory T cells, but they may do so in thymus or in peripheral tissues



Immune system
Humoral immune system - Cellular immune system - Lymphatic system
White blood cells - B cells - Antibodies - Antigen (MHC)
Lymphocytes: T cells (Cytotoxic & Helper) - B cells (Plasma cells & Memory B cells)

  Results from FactBites:
 
Regulatory T cell - Wikipedia, the free encyclopedia (1224 words)
Regulatory T cells (also known as suppressor T cells) are a specialized subpopulation of T cells that act to suppress activation of the immune system and thereby maintain immune system homeostasis and tolerance to self.
Interest in regulatory T cells has been heightened by evidence from experimental mouse models demonstrating that the immunosuppressive potential of these cells can be harnessed therapeutically to treat autoimmune diseases and facilitate transplantation tolerance or specifically eliminated to potentiate cancer immunotherapy.
regulatory T cell population is a subset of the total Foxp3-expressing regulatory T cell population.
Stem cell - Wikipedia, the free encyclopedia (1724 words)
Embryonic stem cells are cultured cells obtained from the undifferentiated inner mass cells of an early stage human embryo (sometimes called a blastocyst, which is an embryo that is between 50 to 150 cells).
Cancer stem cells arising through malignant transformation of adult stem cells are proposed to be the source of some or all tumors and cause metastasis and relapse of the disease.
Embryonic stem cell research is particularly controversial because, with the present state of technology, starting a stem cell 'line' requires the destruction of a human embryo and/or therapeutic cloning.
  More results at FactBites »


 

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