FACTOID # 135: The Pitcairn Islands have the world’s shortest highway system, with only 6.4 kilometers of road. They also have the fourth-fewest main phone lines.
 
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Encyclopedia > Rheb

Rheb is a recently discovered member of the Ras superfamily that may be involved in neural plasticity. This function is novel and not typically associated with the Ras proteins.


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Rheb - Wikipedia, the free encyclopedia (77 words)
Rheb, in molecular biology, is a protein, a recently discovered member of the Ras superfamily that may be involved in neural plasticity.
This function is novel and not typically associated with the Ras proteins.
The name Rheb is short for Ras homolog enriched in brain.
Rheb (2303 words)
Overexpression of Rheb in the developing fly causes dramatic overgrowth of multiple tissues: in the wing, this is due to an increase in cell size; in cultured cells, Rheb overexpression results in accumulation of cells in S phase and an increase in cell size.
Rheb is required in the whole organism for viability (growth) and for the growth of individual cells.
Consistent with this interpretation, flies with reduced Rheb activity are hypersensitive to rapamycin, an inhibitor of the growth regulator target of rapamycin (TOR), a kinase required for growth factor-dependent phosphorylation of ribosomal S6 kinase (S6K).
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