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She is best remembered as the wife and helpmate of Robert “Fighting Bob” La Follette -- a prominent Progressive Republican politician both in Wisconsin and on the national scene -- and as co-editor with her husband of "La Follette’s Weekly Magazine".
The ceremony was performed by a Unitarian minister and by mutual agreement, the word “obey” was omitted from the marriage vows.
Her other children were Robert Jr., born in 1895, who succeeded his father as Senator; Philip, born in 1897, who became Governor of Wisconsin; and Mary, born in 1899.
In 1924 LaFollette again ran for President of the United States, this time as a Progressive, but came in third after incumbent President Calvin Coolidge and Democratic candidate John W. Davis, carrying only Wisconsin.
LaFollette died several months later; his son, Robert M. La Follette, Jr.
In 1909, La Follette and his wife, Belle Case LaFollette, founded the publication La Follette's Weekly.