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Encyclopedia > Ross procedure

The Ross procedure (or pulmonary autograft) is a cardiac surgery operation where a diseased aortic valve is replaced with the person's own pulmonary valve. A pulmonary homograft (valve taken from a cadaver) is then used to replace the patient's own pulmonary valve. Pulmonary autograft replacement of the aortic valve is the operation of choice in infants and children, but its use in adults remains controversial.[1] Cardiac surgery is surgery on the heart, typically to treat complications of ischemic heart disease (e. ... The aortic valve is one of the valves of the heart. ... The pulmonary valve (or pulmonic valve) is the semilunar valve of the heart that lies between the right ventricle and the pulmonary artery and has three cusps. ... A cadaver is a dead body. ...

Contents

History

The Ross procedure is named after Dr. Donald Ross - a pioneer in cardiac surgery in the UK - who proposed the procedure in 1962[2] and first performed it in 1967. Donald Ross (1872-1948) was one of the most significant golf course designers in the history of the sport. ...


Advantages / Disadvantages

Advantages

  • Freedom from thromboembolism without the need for anticoagulation.
  • The valve grows as the patient grows (i.e. children).
  • Favourable hemodynamics.
  • No foreign material present in the valve.

Thrombosis is the formation of a clot or thrombus inside a blood vessel, obstructing the flow of blood through the circulatory system. ... An anticoagulant is a substance that prevents coagulation; that is, it stops blood from clotting. ... Hemodynamics is concerned with the forces generated by the heart and the motion of blood through the cardiovascular system. ...

Disadvantages

  • Single valve disease (aortic) becomes two valve disease (aortic and pulmonary).

Pulmonary valve replacement

One of the main objections to the Ross procedure is the genesis of pulmonary valve disease in addition to aortic valve disease. Protagonists have argued that biological valves implanted in the pulmonary position would be slow to develop dysfunction, and any dysfunction would be well tolerated due to the lower pressures in the right side of the heart. Survival of homografts in the pulmonary position is good (20-year freedom from reoperation of 80%), and homograft dysfunction is infrequently implicated in the observed morbidity and mortality.[3]


Homografts (aortic or pulmonary) should be the replacement of choice; no other valve performed as well in the pulmonary position. Many homograft valves are sterilized with ethylene oxide or irradiation; methods recognized to have deleterious effects on valve performance. The results of the pulmonary autograft procedure are likely to be superior with the use of fresh homograft valves.[3] The chemical compound ethylene oxide is an important industrial chemical used as an intermediate in the production of ethylene glycol and other chemicals, and as a sterilant for foodstuffs and medical supplies. ... Irradiation is the process by which an item is exposed to radiation. ...


See also

A Bentall procedure is a cardiac surgery operation involving composite graft replacement of the ascending aorta and aortic valve, with anastomosis of the coronary arteries into the graft. ... Wikipedia does not yet have an article with this exact name. ...

References

  1. ^ Yacoub M, Klieverik L, Melina G, Edwards S, Sarathchandra P, Bogers A, Squarcia U, Sani G, van Herwerden L, Takkenberg J (2006). "An evaluation of the Ross operation in adults". J Heart Valve Dis 15 (4): 531-9. PMID 16901050. 
  2. ^ Ross D (1962). "Homograft replacement of the aortic valve". Lancet 2: 487. PMID 14494158. 
  3. ^ a b Chambers J, Somerville J, Stone S, Ross D (1997). "Pulmonary autograft procedure for aortic valve disease: long-term results of the pioneer series". Circulation 96 (7): 2206-14. PMID 9337191. 

External links

  • Cardiac Surgery in the Adult - Pulmonary autograft


 

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