Route 25 Length: 86 mi (138 km) Established: 1922 Decommissioned: Present Direction: North-South From: Jackson To: Kennett Cities on route: Jackson Dutchtown Delta Advance Bloomfield Dexter Bernie Malden Holcomb Kennett

Route 25 is a highway in southeastern Missouri. Its northern terminus is at Business Interstate 55/U.S. Highway 61/Route 34 (all multiplexed) in Jackson. Its southern terminus is at U.S. Highway 412/Route 84 in Kennett. Jackson is a city in Cape Girardeau County, Missouri, United States. ... Kennett is a city located in Dunklin County, Missouri, USA. As of the 2000 census, the city had a total population of 11,260. ... Jackson is a city in Cape Girardeau County, Missouri, United States. ... Dutchtown is a village located in Cape Girardeau County, Missouri. ... Delta is a city located in Cape Girardeau County, Missouri. ... Advance is a city located in Stoddard County, Missouri. ... Bloomfield is a city located in Stoddard County, Missouri. ... Dexter is a city located in Stoddard County, Missouri. ... Bernie is a city located in Stoddard County, Missouri. ... Malden is a city in Dunklin County, Missouri, United States. ... Holcomb is a city located in Dunklin County, Missouri. ... Kennett is a city located in Dunklin County, Missouri, USA. As of the 2000 census, the city had a total population of 11,260. ... This article does not cite its references or sources. ... Interstate 55 (abbreviated I-55) is an interstate highway in the central United States. ... The Dubuque-Wisconsin Bridge, Dubuque, Iowa. ... A multiplex or concurrency on a road network occurs where a single physical road carries two or more different highway, motorway, or other road numbers. ... Jackson is a city in Cape Girardeau County, Missouri, United States. ... United States Highway 412 is an east-west United States highway. ... Kennett is a city located in Dunklin County, Missouri, USA. As of the 2000 census, the city had a total population of 11,260. ...

Missouri 25 was one of the original 1922 state highways. Its original northern terminus was at Route 9 in Festus. In 1926, with the creation of the U.S. Highway System, Missouri 9 from St. Louis to Hermatite became part of U.S. Highway 61, which was then routed down Missouri 25 to Jackson, moving MO 25's northern terminus to Jackson, too. Festus is a city located in Jefferson County, Missouri. ... Current U.S. Highway shield Current U.S. Highway shield in California The United States Highway System is an integrated system of roads in the United States numbered within a nationwide grid. ... The Dubuque-Wisconsin Bridge, Dubuque, Iowa. ...

Until US 412 was designated across the southernmost section, "the Bootheel", of Missouri, supplanting this highway south and west of Kenett. Missouri 25 passed Senath and Arbyrd, taking a sharp westward turn and heading across the St. Francis River and the Arkansas border, feeding westward along the former Highway 25 (now US 412) toward Paragould, Arkansas. Senath is a city located in Dunklin County, Missouri. ... Arbyrd is a city located in Dunklin County, Missouri. ... The Saint Francis River is a tributary of the Mississippi River in southeastern Missouri and northeastern Arkansas in the United States. ... Official language(s) English Capital Little Rock Largest city Little Rock Area  Ranked 29th  - Total 53,179 sq mi (137,732 km²)  - Width 239 miles (385 km)  - Length 261 miles (420 km)  - % water 2. ... Paragould is a city located in Greene County, Arkansas. ...