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Patent 6,506,407 (2806 words) |
 | Saccharides that have conventionally been used as components of preparations are degraded by the digestive enzymes in the gastrointestinal tract or directly absorbed from the gastrointestinal tract. |
| The saccharide (c) used in the present invention, which is degraded by enterobacteria in the lower part of the gastrointestinal tract to generate an organic acid, is not limited by whether it is a monosaccharide or a polysaccharide as long as it is rapidly degraded by enterobacteria to generate an organic acid. |
| It is recommended therefore that a composition containing the organic acid-generating saccharide (c) and a drug (b) is coated with the organic acid-soluble polymer material (a) or a composition comprising a drug (b) coated with the polymer material (a) and the organic acid-generating saccharide (c) are coated with a water permeable release-controlling material (e). |
| Energetics of galactose- and glucose-aromatic amino acid interactions: Implications for binding in galactose-specific ... (4146 words) |
| The orientation of the saccharide relative to the aromatic |
| The position-orientation of the bound saccharide with respect to the aromatic residue is similar in these three proteins of the galectin family. |
| The relative position-orientations of the saccharide that are |
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