Samuel Smith, or Sam Smith can refer to any of the following:

• Samuel Smith (brewer), as well as the brewery he founded and the beer it produces:
  • Samuel Smith (brewery)
• Samuel Smith (Maryland) (1752 - 1839), American Senator and Representative from Maryland
• Samuel Smith (Pennsylvania), US Representative from Pennsylvania (1805-1911)
• Samuel Smith (New Hampshire) (1765-1842), US Representative from New Hampshire
• Samuel Smith (Upper Canada) (1756 - 1826) Administrator of Upper Canada (1817-1818)
• Sam Smith (journalist) (b. 1937) American journalist and activist
• Sam "I'm So Hood" Smith (1975-Present) Rap Artist involved in fued with NWA
• Samuel A. Smith (1795-1861), US Representative from Pennsylvania
• Samuel Axley Smith (1822-1863), US Representative from Tennessee
• Samuel H. Smith (educator), former President of Washington State University
• Samuel Harrison Smith (1808 - 1844) brother of Joseph Smith, Jr. and early leader in the Latter Day Saint movement
• Samuel William Smith (1852 - 1931), American politician, former Senator from Michigan

Also: Samuel Smith was a 19th century English brewer, whose name survives in that of the brewery he founded (Samuel Smiths Old Brewery), and in the names of its products. ... Shires delivering beer A bottle of Samuel Smiths Oatmeal Stout. ... Samuel Smith Samuel Smith (July 27, 1752 - April 22, 1839) was a United States Senator and Representative from Maryland, as well as a former mayor of Baltimore, Maryland, and a general in the Maryland Militia. ... Samuel Smith (December 27, 1756 - October 20, 1826) was an army officer, politician and colonial administrator in Upper Canada. ... Upper Canada Village in Morrisburg, Ontario Upper Canada is an early name for the land at the upstream end of the Saint Lawrence River in early North America – the territory south of Lake Nipissing and north of the St. ... Sam Smith (born 1937) is an American journalist and political activist who was an early pioneer in alternative media. ... Samuel H. Smith was the eighth president of Washington State University, serving for fifteen years (July 1, 1985 - June 8, 2000). ... Samuel Harrison Smith (1808–1844) was one of the younger brothers of Joseph Smith, Jr. ... Joseph Smith, Jr. ... The Latter Day Saint movement (a superset of Mormonism, the Mormonism movement or the Mormon movement) is a religious movement beginning in the early 19th century that led to the set of doctrines, practices, and cultures called Mormonism and to the existence of numerous churches, the majority of which call... Samuel William Smith (23 August 1852-13 June 1931), was an American politician. ...

• Samantha Smith (1972 - 1985) Goodwill Ambassador to the Soviet Union
• Samantha Smith (tennis) (b. 1971) British tennis player