San Polo is the smallest of the six sestieri of Venice, covering just 86 acres (350,000 m²) along the Grand Canal. It is one of the oldest parts of the city, having been settled before the ninth century, when it and San Marco formed part of the Realtine Islands. The sestiere is named for the Church of San Polo.
The district has been the site of Venice's main market since 1097, and connected to the right bank of the city by a Rialto bridge since the thirteenth century. The western part of the quarter is now known for its churches, while the eastern part, sometimes just called the Rialto, is known for its palaces and smaller houses.
San Sano seems not to be mentioned in any documents, with the exception of its church, which appears in the lists of the papal tithes for year 1276-1277.
Polo in Rosso, a parish church recorded since 1070 in the maps of Coltibuono and conferred on the bishop of Fiesole in 1102 by Pasquale II.
The church of San Martino located there was noted in the 13 C and preserves a truncated tower and another stone building with numerous original arched apertures.