The Selkirk Rex is a breed of cat with highly curled hair, including the whiskers (vibrissae). Unlike the Devon Rex and Cornish Rex, the hair is of normal length and not partly missing, and there are longhair and shorthair varieties. Also unlike the other Rexes, the Selkirk gene is dominant.

The breed originated with a cat named Miss DePesto, who was bred to a Persian, producing three Selkirk Rexes and three straight-haired cats.