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Encyclopedia > Semiconservative replication
A summary of the three postulated methods of DNA synthesis
A summary of the three postulated methods of DNA synthesis

'Semiconservative replication describes the method by which DNA is replicated in all known cells. This method of replication was one of three proposed models[citation needed] of DNA replication: Image File history File links DNAreplicationModes. ... Image File history File links DNAreplicationModes. ... The structure of part of a DNA double helix Deoxyribonucleic acid (DNA) is a nucleic acid that contains the genetic instructions for the development and function of living organisms. ... This article or section is in need of attention from an expert on the subject. ...

  • Conservative replication would leave the two original template DNA strands together in a double helix and would produce a copy composed of two new strands containing all of the new DNA base pairs.
  • Dispersive replication would produce two copies of the DNA, both containing distinct regions of DNA composed of either both original strands or both new strands.
  • Semiconservative replication would produce two copies that each contained one of the original strands and one entirely new strand.

The deciphering of the structure of DNA by Watson and Crick in 1953 suggested that each strand of the double helix would serve as a template for synthesis of a new strand. However, there was no way of guessing how the newly synthesized strands might combine with the template strands to form two double helical DNA molecules. The semiconservative model seemed most reasonable since it would allow each daughter strand to remain associated with its template strand. That the semiconservative model was correct was verified by the Meselson-Stahl experiment and other even more revealing experiments that allowed for autoradiographic visualization of the distribution of old and new strands within replicated chromosomes. Decipherment is the analysis of documents written in ancient languages, where the language is unknown, or knowledge of the language has been lost. ... A summary of the three postulated methods of DNA synthesis The Meselson-Stahl experiment was an experiment by Matthew Meselson and Franklin Stahl to prove that DNA replication was semiconservative. ...


See also


  Results from FactBites:
 
Replication - Wikipedia, the free encyclopedia (212 words)
In finance option replication is the trading strategy used to ensure at a certain date the payoff of an option without trading this option.
Replication (computer science), the use of redundant resources to improve reliability, fault-tolerance, or performance.
Replications should not be confused with repeated measurements which refer literally taking several measurements of a single occurrence of a phenomenon.
  More results at FactBites »


 

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