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The term "sequence analysis" in biology implies subjecting a DNA or peptide sequence to sequence alignment, sequence databases, repeated sequence searches, or other bioinformatics methods on a computer. part of a DNA sequence A DNA sequence (sometimes genetic sequence) is a succession of letters representing the primary structure of a real or hypothetical DNA molecule or strand, The possible letters are A, C, G, and T, representing the four nucleotide subunits of a DNA strand (adenine, cytosine, guanine...
Peptide sequence or amino acid sequence is the order in which amino acid residues, connected by peptide bonds, lie in the chain. ...
Sequence alignment is an arrangement of two or more sequences, highlighting their similarity. ...
In the field of bioinformatics, a sequence database is a large collection of DNA, protein, or other sequences stored on a computer. ...
In the study of DNA sequences, one can distinguish two main types of repeated sequence: Tandem repeats: Satellite DNA, Minisatellite, Microsatellite; Interspersed repeats: SINE (Short INterspersed Elements), LINE (Long INterspersed Elements). ...
Map of the human X chromosome (from the NCBI website). ...
Sequence analysis in molecular biology and bioinformatics is an automated, computer-based examination of characteristical fragments, e.g. of a DNA-strand. It basically includes five biologically relevant topics: Molecular biology is the study of biology at a molecular level. ...
The general structure of a section of DNA Deoxyribonucleic acid (DNA) is a nucleic acid that contains the genetic instructions for the biological development of a cellular form of life or a virus. ...
- the comparison of sequences in order to find similar sequences (sequence alignment)
- identification of gene-structures, reading frames, distributions of introns and exons and regulatory elements
- prediction of protein structures
- genome mapping
- comparison of homologous sequences to construct a molecular phylogeny
In chemistry, sequence analysis comprises techniques used to do determine the sequence of a polymer formed of several monomers. In molecular biology and genetics, the same process is called simply "sequencing." In genetics, a sequence motif is a nucleotide or amino-acid sequence pattern that is widespread and has, or is conjectured to have, a biological significance. ...
In biology, a reading frame is a contiguous and non-overlapping set of three-nucleotide codons in DNA or RNA. There are 3 possible reading frames in a strand. ...
Diagram of the location of introns and exons within a gene. ...
An exon is any region of DNA within a gene, that is transcribed to the final messenger RNA (mRNA) molecule, rather than being spliced out from the transcribed RNA molecule. ...
Gene regulation is the general term for cellular control of protein synthesis at the DNA-RNA transcription step. ...
Proteins are amino acid chains, made up from 20 different L-α-amino acids, also referred to as residues, that fold into unique three-dimensional protein structures. ...
In biology the genome of an organism is the whole hereditary information of an organism that is encoded in the DNA (or, for some viruses, RNA). ...
In biology, two or more structures are said to be homologous if they are alike because of shared ancestry. ...
Molecular phylogeny is the use of the structure of molecules to gain information on an organisms evolutionary relationships. ...
Chemistry (from Greek Ïημεία khemeia[1] meaning alchemy) is the science of matter at the atomic to molecular scale, dealing primarily with collections of atoms, such as molecules, crystals, and metals. ...
Polymer is a term used to describe large molecules consisting of repeating structural units, or monomers, connected by covalent chemical bonds. ...
In chemistry, a monomer (from Greek mono one and meros part) is a small molecule that may become chemically bonded to other monomers to form a polymer. ...
Molecular biology is the study of biology at a molecular level. ...
Genetics (from the Greek genno γεννÏ= give birth) is the science of genes, heredity, and the variation of organisms. ...
In genetics and biochemistry, sequencing means to determine the primary structure (or primary sequence) of an unbranched biopolymer. ...
External sites
Sequence analysis web tools This bioinformatics-related article is a stub. You can help Wikipedia by expanding it. Map of the human X chromosome (from the NCBI website). ...
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