Sequence profiling Tools in bioinformatics refer to all those software tools (web-based/downloadable) that provide a brief overview on all related information about an input sequence. Bioinformatics or computational biology is the use of techniques from applied mathematics, informatics, statistics, and computer science to solve biological problems. ... Computer software (or simply software) refers to one or more computer programs and data held in the storage of a computer for some purpose. ...

The advent of post-genomics era has given rise to a range of web based tools and software to handle the deluge of biological information. A simple web-search returns any number of such services and software tools ranging from the popular public domains e.g. NCBI, ExPASy, Ensembl, PDB etc to private research group sites e.g. eF-site, Dipole moment server, SuperPose, REBASE. However, most of these remain obscure/under-explored to a bench-top molecular biologist who most often would like to quickly know which record in the BLAST report is useful for further analysis (given that the first few hits are already known) OR like to have a guess at what would a newly found ORF look like after translation. Genomics is the study of an organisms genome and the use of the genes. ... The National Center for Biotechnology Information (NCBI) is part of the US National Library of Medicine (NLM), which is a branch of the US National Institutes of Health. ... EnsEMBL is a research project aiming to develop a software system which produces and maintains automatic annotation on selected eukaryotic genomes. ... PDB can be an acronym for any of the following: the Presidents Daily Briefing the Protein Data Bank the trio Pastorius, Dennard, and Bullock, and a jazz album by that trio a file format, Palm database, generally used to store data for an application a (proprietary) Microsoft file format... Blast can be an initialism: An algorithm, used in bioinformatics, see BLAST. BLAST can also mean Berkeley Lazy Abstraction Software Verification Tool. [1] The journal of the Vorticism movement, published in 1914 and 1915: see BLAST. A figure from Norse mythology, see Hrimthurs. ... Orf is a viral disease found primarily in sheep and goats that is caused by a parapox virus. ...

In other words the user often needs an interface that acts like a Propaedia or a gateway, giving him a brief overview about his sequence (DNA/RNA/protein) while still allowing advanced operations without having to leave the browser session. Sites like Entrez provide this kind of facility for text related searches in biomedical field. A Propaedia is an information resource providing a birds eyeview on different aspects of any given topic. ... Space-filling model of a section of DNA molecule Deoxyribonucleic acid (DNA) or deoxyribose nucleic acid is a nucleic acid that contains the genetic instructions specifying the biological development of all cellular forms of life (and many viruses). ... Ribonucleic acid (RNA) is a nucleic acid consisting of a string of covalently-bound nucleotides. ... A representation of the 3D structure of myoglobin, showing coloured alpha helices. ... The Entrez Global Query Cross-Database Search System allows access to databases at the National Center for Biotechnology Information (NCBI) website. ...

External links

• Entrez (http://www.ncbi.nlm.nih.gov/gquery/gquery.fcgi?itool=toolbar/) - A keyword indexing tool for biomedical terms across NCBI daatabases
• Sequerome (http://Sequerome.georgetown.edu) - A Sequence Profiling Tool across databases
• Bioinformatic Harvester (http://harvester.embl.de/) - A Sequence Profiling Tool across databases
• InstaSeq (http://bioinformatics.georgetown.edu/InstaSeq.htm) - You can actually enter a sequence data and search the World Wide Web - powered by Google search!
• Google (http://www.google.com/) - Needs no introduction... Try pasting any sequence into google you might lucky