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Encyclopedia > Seroquel

Quetiapine (kwe-TYE-a-peen), marketed by AstraZeneca with the brand name Seroquel, is one of the atypical antipsychotics. Quetiapine has FDA and international approvals for the treatment of schizophrenia and acute mania in bipolar disorder. It is used "off-label" to treat other disorders, such as post-traumatic stress disorder, and as a sedative for those with sleep disorders.

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SEE BNF FOR FURTHER NOTES ON SEROQUEL. CHECK http://www.bnf.org/bnf


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What is Seroquel? (413 words)
Seroquel (quetiapine fumarate), an oral medication for the management of the manifestations of psychotic disorders (including schizophrenia), was cleared by the FDA for marketing on September 29, 1997.
Findings from extensive clinical trials have shown Seroquel to be effective in the treatment of both positive (e.g., delusions, thought disorder, and hallucinations) and negative (e.g., social withdrawal, lack of energy, apathy, and reduced ability to express emotion) symptoms of schizophrenia.
Seroquel should be used with particular caution in patients with known cardiovascular disease, cerebrovascular disease, or conditions associated with hypotension.
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