Sextasy is a common name for a drug combination of ecstacy (methylenedioxymethamphetamine), and sildenafil citrate (Viagra), which is a PDE5 inhibitor and vasodilator used for erectile dysfunction. Sextasy can be ingested as two separate mediums (such as tablets) or they may be crushed and combined for insufflation or insertion into a capsule. Sextasy is a slang term for the combination, refering to ecstasy and sex combined, sex refering to the effects of the Viagra. MDMA (3,4-methylenedioxy-N-methylamphetamine), most commonly known today by the street name ecstasy, (often abbreviated to E, X, or XTC) is a semisynthetic entactogen of the phenethylamine family. ... Sildenafil citrate, sold under the names Viagra, Revatio and generically under various other names, is a drug used to treat male erectile dysfunction (impotence) and pulmonary arterial hypertension (PAH), developed by the pharmaceutical company Pfizer. ... // ... A phosphodiesterase type 5 inhibitor, often shortened to PDE5 inhibitor, is a drug used to block the degradative action of phosphodiesterase type 5 on cyclic GMP in the smooth muscle cells lining the blood vessels supplying the corpus cavernosum of the penis. ... Vasodilation is where blood vessels in the body become wider following the relaxation of the smooth muscle in the vessel wall. ...

Physiological Interactions

Sextasy's inclusion of Viagra is thought to minimize or eliminate the effect of MDMA (Ecstasy) on the ability to develop an erection. Ecstasy effects areas in the brain that ultimately induce a significant period of euphoria, the mechanism is thought to be causing a mass amount of serotonin to flood the neuroreceptors. ecstasy and religious ecstasy MDMA, most commonly known today by the street name ecstasy, is a synthetic entactogen of the phenethylamine family whose primary effect is to stimulate the brain to rapidly secrete large amounts of serotonin, causing a general sense of openness, empathy, energy, euphoria, and well-being. ...

Risks

Immediate psychological effects last from four to six hours and may include euphoria, anxiety, insomnia, and/or paranoia. Immediate physical effects include muscle tension, jaw clenching, nausea, nystagmus (involuntary eye movement), tremors, increased heart rate, and chills. Due to increases in heart rate and blood pressure, a user's body temperature may effectively rise and lead to dehydration, hyperthermia, and possible seizures. Since PDE5 inhibitors work by vasodilation, headaches are a common side effect of PDE5 inhibitors alone. Viagra alone can in some patients cause priapism, an erection that lasts more than four hours. Priapism is painful and can cause lasting damage to the penis. [1] The blood vessels are part of the circulatory system and function to transport blood throughout the body. ... Fresco of Priapus, House of the Vettii, Pompeii. ...

References

• The 'sextasy' craze. Clubland's dangerous party mix: Viagra and ecstasy. Newsweek. 2002 Jun 3;139(22):30.
• Curtis, Kim, and Margie Mason. Mixing Viagra, ‘Party Pills’ a Dangerous New Trend. Ottawa Citizen 25 June 2002, final ed., sec. News: A14. LexisNexis Academic. LexisNexis. Clark Memorial Lib., Portsmouth, OH. 15 Feb. 2006 <http://web.lexis-nexis.com/universe>.
• Viagra Joining Pill Party. The Associated Press [Victoria, British Columbia] 22 July 2002, final ed., sec. Life: C5. LexisNexis Academic. LexisNexis. Clark Memorial Lib., Portsmouth, OH. 15 Feb. 2006 <http://web.lexis-nexis.com/universe>.
• ECSTASY PLUS VIAGRA EQUALS DANGER, COPS SAY. Edmonton Sun [Alberta, Canada] 14 Nov. 2002, final ed., sec. News: 5. LexisNexis Academic. LexisNexis. Clark Memorial Lib., Portsmouth, OH. 15 Feb. 2006 <http://web.lexis-nexis.com/universe>.
• Hunter, Stuart, and Jack Keating. Ravers Beware: Trail Mix Could Kill. The Vancouver Province [British Columbia] 9 Sept. 2002, final ed., sec. News: A4. LexisNexis Academic. LexisNexis. Clark Memorial Lib., Portsmouth, OH. 15 Feb. 2006 <http://web.lexis-nexis.com/universe>.