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short tandem repeat: Information from Answers.com (525 words) |
 | A short tandem repeat (STR) in DNA is a class of polymorphisms that occurs when a pattern of two or more nucleotides are repeated and the repeated sequences are directly adjacent to each other. |
| The STRs in use today for forensic analysis are all tetra- or penta-nucleotide repeats (4 or 5 repeat units), as these give a high degree of error-free data while being robust enough to survive degradation in non-ideal conditions. |
| Shorter repeat sequences tend to suffer from artifacts such as stutter and preferential amplification, as well as the fact that several genetic diseases are associated with tri-nucleotide repeats such as Huntington's disease. |
| [3] Tandem Repeats (332 words) |
| Tandem repeats are an array of consecutive repeats. |
| Its repeat unit is 171 bp and the repetitive region accounts for 3-5% of the DNA in each chromosome. |
| Microsatellites are also known as short tandem repeats (STR), because a repeat unit consists of only 1 to 6 bp and the whole repetitive region spans less than 150 bp. |
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