Submucosa
LAYERS: serosa longitudinal muscle myenteric plexus circular muscle submucosal plexus submucosal mucosal

In the gastrointestinal tract. The layer of loose connective tissue [comprised of: collagen type I fibers, "reticular" or collagen type III fibers (which join connective tissue to other tissues), elastic fibers, and adipose tissue] that supports the mucosa [epithelium, lamina propria (also just loose supporting tissue but with diffuse lymphocyte and plasma cell populations), and muscularis mucosae (several thin layers of smooth muscle fibers oriented in different ways which keeps the mucosal surface and underlying glands in a constant state of gentle agitation to expel contents of glandular crypts and enhance contact between epithelium and the contents of the lumen)] as well as joins the mucosa to the bulk of underlying smooth muscle (fibers running circularly within layer of longitudonal muscle). A serous membrane is a very thin layer of cells (usually one row) covering internal body cavity. ... Part of the enteric nervous system, Auerbachs plexus exists between the longitudinal and circular layers of muscle in the gastrointestinal tract and provides motor innervation to both layers and secretomotor innervation to the mucosa. ... The mucous membranes (or mucosae; singular: mucosa) are linings of ectodermic origin, covered in epithelium, and are involved in absorption and secretion. ... Loose connective tissue is the most common type of connective tissue in vertebrates. ... The mucous membranes (or mucosa) are linings of ectodermic origin, covered in epithelium, that line various body cavities and internal organs. ...

Blood vessels, lymphatic vessels, and nerves (all supplying the mucosa) will run through here. Tiny parasympathetic ganglia are scattered around forming the submucosal plexus (or "Meissner's plexus") where preganglionic parasympathetic neurons synapse with postganglionic nerve fibers that supply the muscularis mucosae. Section of mucous membrane of human rectum. ...

The submucosa in endoscopy

Endoscopy and radial endoscopic ultrasound images of submucosal tumour in mid-esophagus. The submucosa is seen as a dark ring on the ultrasound image.

Identification of the submucosa plays an important role in diagnostic and therapeutic endoscopy, where special fibre-optic cameras are used to perform procedures on the gastrointestinal tract. Abnormalities of the submucosa, such as gastrointestinal stromal tumors, usually show integrity of the mucosal surface. The submucosa is also identified in endoscopic ultrasound to identify the depth of tumours and to identify other abnormalities. An injection of dye, saline, or epinephrine into the submucosa is imperative in the safe removal of certain polyps. Endoscopic mucosal resection involves removal of the mucosal layer, and in order to be done safely, a submucosal injection of dye is performed to ensure integrity at the beginning of the procedure. Endoscopic still of esophageal ulcers seen after banding of esophageal varices, at time of esophagogastroduodenosocopy In medicine (gastroenterology), esophagogastroduodenoscopy is a diagnostic endoscopic procedure that visualises the upper part of the gastrointestinal tract up to the duodenum. ... Endoscopic ultrasound is an ultrasound that is placed into the stomach and duodenum via the upper GI tract. ... The esophagus (also spelled oesophagus/Å“sophagus), or gullet is the muscular tube in vertebrates through which ingested food passes from the mouth area to the stomach. ... Endoscopic images of a duodenal ulcer Endoscopy means looking inside and refers to looking inside the human body for medical reasons. ... Fiber Optic strands An optical fiber in American English or fibre in British English is a transparent thin fiber for transmitting light. ... The gastrointestinal tract or digestive tract, also referred to as the GI tract or the alimentary canal, (nourishment canal) or the gut, is the system of organs within multicellular animals which takes in food, digests it to extract energy and nutrients, and expels the remaining waste. ... Endoscopic image of GIST in fundus of stomach, seen on retroflexion. ... An open surface with X-, Y-, and Z-contours shown. ... Endoscopic ultrasound is an ultrasound that is placed into the stomach and duodenum via the upper GI tract. ... Polyp of sigmoid colon as revealed by colonoscopy. ...

Bladder Image File history File links Illu_bladder. ...

External links

• Dictionary at eMedicine submucosa
• Organology at UC Davis Digestive/mammal/system1/system5 - "Mammal, whole system (LM, Low)"