Hyperthermia is an acute condition resulting from excessive exposure to heat, it is also known as heat stroke or sunstroke. The homeothermal regulatory mechanisms become overwhelmed and unable to effectively deal with the heat, and body temperature climbs uncontrollably. This is a serious medical emergency that requires immediate hospitalization. Body temperatures above 40°C (104°F) are considered life-threatening. At 41 °C (106 °F), brain death begins, and at 45°C (113 °F) death is nearly certain. Internal temperatures above 50 °C (122 °F) will cause rigidity in the muscles and, therefore, certain immediate death.
Signs include increasing body temperature (hyperpyrexia), dehydration and lack of sweating, seizures, collapse and decreased consciousness which proceeds rapidly to multi-organ failure and death as the brain 'cooks'.
Heat stroke comes on suddenly. Vigilance is required in order to prevent and treat this rapidly dangerous condition. The first and foremost symptom of a serious heat stroke is that the patient has stopped sweating. Because the evaporation of water is endothermic, body heat is taken away by the evaporation of sweat. When the body is no longer capable of sweating, core temperature will begin to rise immediately and swiftly. The victim will become confused, often hostile, and may seem drunk. The temperature must be lowered immediately, the victim must be hydrated by drinking water. Other substances may be used in place of water if absolutely necessary, however alcohol and caffeine should be avoided at all costs.
A preceding condition is known as heat prostration or heat exhaustion.
Sunstroke is a life-threatening condition in which the body's heat-regulating system fails, due to exposure to high temperatures.
Sunstroke can occur when the body's mechanisms to rid itself of excess heat are overwhelmed by a very hot or humid environment, or strenuous physical activity.
People particularly susceptible to sunstroke are young children, the elderly, individuals not used to physical activity and concomitant excessive sun exposure (such as overseas visitors walking in the mountains in Africa), people suffering from certain chronic medical conditions, and those involved in certain sporting activities.