A sustentacular cell (also refered to as "Sertoli Cells")is a biological cell which is part of an epithelium that surrounds the Seminiferous Tubule and lies within a lobule in the testes. there are several important functions of the sertoli cells; Maintaining the blood-testis barrier The location of the seminiferous tubules are isolated from regular circulation by a Blood-testis barrier (similar to the blood-brain barrier). This is because the developing spermatids are haploids that contain only 23 individual chromosomes, and, without the blood-testis barrier the immune system would identify these cells as abnormal cells and destroy them. Sertoli cells regulate the transport of materials across BTB and regulate the environment surrounding the spermatocytes and spermatids in order to maintain a very stable environment. the environment at the lumen of a seminiferous tubule contains a fluid that is very differnet from interstitial fluid. Tubular fluid is high in androgens, estrogens, potassium, and amino acids Drawing of the structure of cork as it appeared under the microscope to Robert Hook from Micrographia which is the origin of the word cell. Cells in culture, stained for keratin (red) and DNA (green). ... Types of epithelium This article discusses the epithelium, an animal anatomical structure. ...
Support Spermatogenesis
and that supports other cells. Examples of sustentacular cells are Sertoli cells, which support germ cells in the seminiferous tubules, or the cells of the olfactory epithelium, which help in olfaction. A Sertoli cell (a kind of sustentacular cell) is a nurse cell of the testes which is part of a seminiferous tubule. ... A germ cell is a kind of cell that is part of the germline, and is involved in the reproduction of organisms. ... This article needs to be wikified. ... The olfactory epithelium is a specialized epithelial tissue inside the nasal cavity that is involved in smell. ... Olfaction (the sense of smell) is the detection of chemicals dissolved in air. ...
This cell type is (as the name implies) not part of the sperm cell line, but a sort of "nurse" cell that sustains the proper environment for spermatozoa to develop.
The extensive branching nature of the cell's cytoplasm and its role in isolating the haploid components of the system from the rest of the body were not understood before the advent of the EM.
The sustentacularcells have as one of their chief roles the prevention of autoimmune reactions and the maintenance of two separate compartments in which the different stages of the sperm cycle can exist under optimal conditions.
A Sertoli cell (a kind of sustentacularcell) is a 'nurse' cell of the testes, and which is part of a seminiferous tubule.
The junctions of Sertoli cells form the blood-testis barrier, a structure that partitions the interstitial blood compartment of the testis from the adluminal compartment of the seminiferous tubules.
Sertoli cells are called so because of their eponym Enrico Sertoli, an Italian physiologist who discovered them in 1865.