Syncytiotrophoblasts are cells found in the placenta of human embryos. They are the outer syncytial layer of the trophoblasts and actively invade the uterine wall. They forms the outermost fetal component of the placenta (also known as syntrophoblast) and massively increases the surface area available for nutrient exchange between the mother and the foetus. The placenta is an ephemeral (temporary) organ present only in female placental mammals during gestation (pregnancy). ... The trophoblast (from Greek threphein: to feed) is considered to be the first of all embryonic annexes. ... Female internal reproductive anatomy The uterus or womb is the major female reproductive organ of most mammals, including humans. ... Fetus at eight weeks Foetus redirects here. ...
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CYTOTROPHOBLAST
Functional Differentiation of Placental Syncytiotrophoblasts during Baboon Pregnancy: Developmental Expression of Chorionic Somatomammotropin Messenger Ribonucleic Acid and Protein Levels (Journal of Endocrinology & Metabolism
The syncytiotrophoblast is the outer syncytial layer of the trophoblast, which is an extraembryonic tissue that supplies nutrition to the embryo.
This suggests that extrinsic glycoproteins on the syncytiotrophoblast membrane help to mediate focal foetal allograft immunosuppression through the regulation of specific cytokine activities, and that the attached oligosaccharides are important in determining the clinical outcome of this activity.
Syncytiotrophoblast microvilli membranes were isolated from human term placentae within one hour of delivery using the method of Smith et al., Nature 252, 302-303 (1974).
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