Synthroid is the brand name used by Abbott Laboratories for levothyroxine sodium (T4, a synthetic thyroid hormone) product. Levothyroxine is the basic T4 thyroid hormone responsible for metabolism. Patients who suffer from hypothyroidism, either for endogenous disease or after radioactive iodine ablation or thyroid resection, require exogenous thyroid hormone, and Synthroid is the most prescribed brand of T4. Synthroid was marketed in 1955^[1], but was not FDA approved at that time as it was considered "generally regarded safe". In the 1990s, in response to various complaints^[2], all levothyroxine preparations were required to undergo the formal FDA approval process. Synthroid was approved by the FDA on 2002-07-24.^[3] A brand is a collection of images and ideas representing an economic producer; more specifically, it refers to the concrete symbols such as a name, slogan, and design scheme. ... Abbott Laboratories NYSE: ABT is a pharmaceuticals and health care company. ... Levothyroxine, also known as L-thyroxine, synthetic T4 or simply 3,5,3,5-tetraiodo-L-thyronine, is a synthetic form of thyroxine (thyroid hormone). ... General Name, Symbol, Number sodium, Na, 11 Chemical series alkali metals Group, Period, Block 1, 3, s Appearance silvery white Atomic mass 22. ... The thyroid hormones, thyroxine (T4) and triiodothyronine (T3), are tyrosine-based hormones produced by the thyroid gland. ... The thyroid hormones, thyroxine (T4) and triiodothyronine (T3), are tyrosine-based hormones produced by the thyroid gland. ... Hypothyroidism is the disease state caused by insufficient production of thyroid hormone by the thyroid gland. ... 1955 (MCMLV) was a common year starting on Saturday of the Gregorian calendar. ... See also 1990s, the band The 1990s decade refers to the years from 1990 to 1999, inclusive, sometimes informally including popular culture from the very late 1980s and from 2000 and beyond. ... This article or section is in need of attention from an expert on the subject. ... For album titles with the same name, see 2002 (album). ... July 24 is the 205th day (206th in leap years) of the year in the Gregorian Calendar, with 160 days remaining. ...

It should be noted that Synthroid was not the first T4 drug produced for patients, and there are numerous generic versions approved by the Food and Drug Administration, but there is great variation in uniformity of production and regularity of therapeutic action among different T4 drugs. Consequently, many endocrinologists and other prescribers specify a specific thyroid hormone brand for their patients to take because thyroid hormone has a narrow therapeutic index. In the United States, Synthroid is the second most prescribed drug. Another commonly prescribed brand-name T4 drug is Levothroid The dosing of Synthroid is one tablet daily, 30 minutes before breakfast. A generic drug (pl. ... This article or section is in need of attention from an expert on the subject. ... Endocrinology is a branch of medicine dealing with disorders of the endocrine system and its specific secretions called hormones. ... The therapeutic index of a medication is a comparison of the amount that causes the therapeutic effect to the amount that causes toxic effects. ... Levothyroxine, also known as L-thyroxine, synthetic T4 or simply 3,5,3,5-tetraiodo-L-thyronine, is a synthetic form of thyroxine (thyroid hormone). ...

Notes

1. ↑  Company Report on Abbott
2. ↑  Dr Mercola's site
3. ↑  FDA approval
4. ↑  Synthroid Profile