Systematic reviews are named as the highest level of medical evidence, by evidence based medicine professionals. Evidence-based medicine is a medical movement based upon the application of the scientific method to medical practice, including long-established existing medical traditions not yet subjected to adequate scientific scrutiny. ...
A systematic review is a summary of the medical literature that uses explicit methods to perform a thorough literature search and critical appraisal of individual studies and that uses appropriate statistical techniques to combine these valid studies.
An understanding of systematic reviews and how to implement them in practice is now mandatory for all professionals involved in the delivery of healthcare.
Cochrane Collaboration founded in 1993, is the name of a group of over 6,000 specialists in health care who systematically review biomedical trials and results of other research. They have offered a handbook for systematic reviewers of intervention, where they suggest each systematic review to be consisted of following main portions: Jump to: navigation, search The Cochrane Collaboration developed in response to Archie Cochranes call for systematic, up-to-date reviews (currently known as systematic reviews) of all relevant randomized clinical trials of health care. ...
Background
Objectives
Methods of the review
Results (usually obtained from meta-analysis of available data)
Conclusion and discussion
There are seven steps for preparing and maintaining a systematic review, as outlined in Cochrane's Handbook: A meta-analysis is a statistical practice of combining the results of a number of studies. ...
Systematicreviews are generally regarded as the highest level of medical evidence by evidence-based medicine professionals.
A systematicreview is a summary of the healthcare literature that uses explicit methods to perform a thorough literature search and critical appraisal of individual studies to identify the valid and applicable evidence, and then uses appropriate techniques to combine these valid studies.
Most systematicreviews are based on a quantitative meta-analysis of available data, but there are also some more qualitative reviews which adhere to the standards for gathering, analyzing and reporting evidence.
Systematicreview is defined as "an efficient scientific technique to identify and summarise evidence on the effectiveness of interventions and to allow the generalisability and consistency of research findings to be assessed and data inconsistencies to be explored".
Because the reviews are largely undertaken by members of SIGN guideline development groups working part time on the project, and within a limited timescale, their coverage of the literature may be more limited than those carried out by dedicated systematicreview groups such as the Cochrane Collaboration.
The systematic literature review procedure is illustrated in Figure 5.1 and an example protocol documenting all aspects of a literature review is shown in Annex E.
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