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Encyclopedia > The Myelin Project

The Myelin Project is a medical project intended to re-generate the nerve's myelin sheath, — a process called remyelination — destroyed in a host of diseases such as multiple sclerosis and the leukodystrophies. Nerves (yellow) Nerves redirects here. ... In neuroscience, myelin is an electrically insulating fatty layer that surrounds the axons of many neurons, especially those in the peripheral nervous system. ... Leukodystrophy refers to progressive degeneration of the white matter of the brain due to imperfect growth or development of the myelin sheath, the fatty covering that acts as an insulator around nerve fiber. ...

Contents

The project's aims

According to their web site,

The Myelin Project aims to accelerate research on myelin repair.

They also are

...working very hard to put ourselves out of business.

Inspiration

The project was inspired by the real-life case of Lorenzo Odone, subject of the movie Lorenzo's Oil. Lorenzo Odone (born May 29, 1978)[1] is a person with Adrenoleukodystrophy (ALD), and is notable because of the quest for a treatment by his parents, Augusto and Michaela Odone. ... // Composition Oleo-erucic acid (Lorenzos oil) is a 4:1 mixture of oleic and erucic acid extracted from olive oil and grapeseed oil respectively. ...


Wikipedia links

Conditions of interest

Adrenoleukodystrophy (ALD) is a degenerative disorder of the fatty white sheath covering nerve fibers, known as myelin. ... Canavan disease is an inherited disorder that causes progressive damage to nerve cells in the brain. ... Krabbe disease is a degenerative disorder that affects the central and peripheral nervous system. ... Metachromatic leukodystrophy (MLD) is the most common form of a family of genetic diseases known as the leukodystrophies, diseases which affect the growth and/or development of myelin, the fatty covering which acts as an insulator around nerve fibres throughout the central and peripherial nervous systems . ... Dirka dirka Pelizaeus-Merzbacher disease (PMD) is a rare central nervous system disorder in which coordination, motor abilities, and intellectual function are delayed to variable extents. ... Phenylketonuria [PKU] is a human genetic disorder (though it is possible to exist in mice), in which the body lacks phenylalanine hydroxylase, the enzyme necessary to metabolize phenylalanine to tyrosine. ...

Treatments investigated

// Composition Oleo-erucic acid (Lorenzos oil) is a 4:1 mixture of oleic and erucic acid extracted from olive oil and grapeseed oil respectively. ...

External links

  • The Myelin Project's home page


 

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