The Three Cities is a collective description of the three fortified cities of Cospicua, Vittoriosa, and Senglea on the Island of Malta, which are enclosed by the massive line of fortification created by the Knights of St John, the Cottonera Lines . Cospicua, city, Malta. ... Fort St Angelo Birgu is a small town in Malta that played a vital role in the Siege of Malta in 1565. ... Senglea is a city in the south of Malta. ... The Knights Hospitaller (the or Knights of Malta or Knights of Rhodes) is a tradition which began as a Benedictine nursing Order founded in the 11th century based in the Holy Land, but soon became a militant Christian Chivalric Order under its own charter, and was charged with the care...