Active site - Binding site - Catalytically perfect enzyme - Coenzyme - Cofactor - EC number - Enzyme catalysis - Enzyme kinetics - Enzyme inhibitor - Lineweaver-Burk plot - Michaelis-Menten kinetics Medical Subject Headings (MeSH) is a huge controlled vocabulary (or metadata system) for the purpose of indexing journal articles and books in the life sciences. ... A representation of the 3D structure of myoglobin, showing coloured alpha helices. ... Ribbon diagram of the enzyme TIM, surrounded by the space-filling model of the protein. ... The active site of an enzyme is the binding site where catalysis occurs. ... A binding site is a region on a protein to which specific ligands bind. ... Catalytically perfect enzyme or kineticall perfect enzyme is an enzyme that catalyzes so efficiently, that almost every time enzyme meets its substrate, the reaction occurs. ... Coenzyme A Coenzymes are small organic non-protein molecules that carry chemical groups between enzymes. ... A cofactor is any substance that needs to be present in addition to an enzyme to catalyze a certain reaction. ... The Enzyme Commission number (EC number) is a numerical classification scheme for enzymes, based on the chemical reactions they catalyze. ... Enzyme catalysis is the catalysis of chemical reactions by enzyme molecules. ... It has been suggested that this article or section be merged with Enzyme. ... HIV protease in a complex with the protease inhibitor ritonavir. ... In biochemistry, the Lineweaver-Burk plot (or double reciprocal plot) is a graphical representation of the Lineweaver-Burk equation of enzyme kinetics, described by Hans Lineweaver and Dean Burk in 1934. ... Michaelis-Menten kinetics describes the kinetics of many enzymes. ...

EC1 Oxidoreductases,O+R+D/list (alcohol oxidoreductases, CH-CH oxidoreductases, peroxidase, oxygenase) - EC2 Transferases/list (methyltransferase, acyltransferase, glycosyltransferase, transaminase, phosphotransferase, polymerase, kinase) - EC3 Hydrolases/list (esterase, DNA glycosylases, glycosidase, protease, acid anhydride hydrolases) - EC4 Lyases/list (carboxy-lyases, aldolase, dehydratase, synthase, adenylate cyclase, guanylate cyclase) - EC5 Isomerases/list (mutase, topoisomerase) - EC6 Ligases/list (DNA ligase, aminoacyl tRNA synthetase) In biochemistry, an oxidoreductase is an enzyme that catalyzes the transfer of electrons from one molecule (the oxidant, also called the hydrogen donor or electron donor) to another (the reductant, also called the hydrogen acceptor or electron acceptor). ... An oxidase is any enzyme that catalyzes an oxidation/reduction reaction involving molecular oxygen (O2) as the electron acceptor. ... A reductase is an enzyme which lowers the activation energy for a reduction reaction. ... A dehydrogenase is an enzyme that oxidizes a substrate by transferring one or more protons and a pair of electrons to an acceptor, usually NAD/NADP or a flavin coenzyme such as FAD or FMN. Common examples of dehydrogenase enzymes in the TCA cycle are pyruvate dehydrogenase, isocitrate dehydrogenase, and... This list contains a list of EC numbers for the first group, EC 1, oxidoreducatases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology. ... Functional group of an alcohol molecule. ... CH-CH oxidoreductases are oxidoreductase enzymes which convert single bonds and double bonds between two carbon atoms. ... Glutathione Peroxidase 1 A peroxidase (eg. ... An oxygenase is any enzyme that oxidizes a substrate by transferring the oxygen from molecular oxygen O2 (as in air) to it. ... In biochemistry, a transferase is an enzyme that catalyzes the transfer of a functional group (e. ... This list contains a list of EC numbers for the second group, EC 2, transferases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology. ... Methyltransferase can refer to: DNA methyltransferase Histone methyltransferase Category: ... Acetyl Acyltransferase is a type of transferase enzyme which acts upon acyl groups. ... Glycosyltransferases are a group of enzymes that act as a catalyst for the transfer of a monosaccharide from a glycosylamine derivative to an acceptor. ... In biochemistry, a transaminase or an aminotransferase is an enzyme that catalyzes a type of reaction between an amino acid and an α-keto acid. ... Phosphotransferase is a category of enzymes with the quality of catalyzing phosphorylation. ... ITaq DNA polymerase A polymerase (EC 2. ... In biochemistry, a kinase is a type of enzyme that transfers phosphate groups from high-energy donor molecules, such as ATP, to specific target molecules (substrates); the process is termed phosphorylation. ... In biochemistry, a hydrolase is an enzyme that can break a chemical bond by hydrolysis. ... This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology. ... An esterase is an hydrolase enzyme that splits esters into a acid and an alcohol in a chemical reaction with water called hydrolysis. ... DNA glycosylases are a family of enzymes involved in base excision repair. ... Glycoside hydrolases (also called glycosidases) catalyze the hydrolysis of the glycosidic linkage to generate two smaller sugars. ... Proteases (proteinases, peptidases, or proteolytic enzymes) are enzymes that break peptide bonds between amino acids of proteins. ... Acid anhydride hydrolases are a class of hydrolase enzymes catalyzes the hydrolysis of a acid anhydride bond. ... In biochemistry, a lyase is an enzyme that breaks various chemical bonds by means other than hydrolysis and oxidation, often forming a new double bond or a new ring structure. ... This list contains a list of EC numbers for the fourth group, EC 4, lyases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology. ... Carboxy-lyases, also known as decarboxylases, are carbon-carbon lyases that add or remove a carboxyl group from organic compounds. ... Aldolase is an enzyme which catalyses the aldol reaction: The substrate, fructose 1,6-bisphosphate (F-1,6-BP) is broken down into glyceraldehyde 3-phosphate and dihydroxyacetone phosphate (DHAP). ... Dehydratase is an enzyme that catalyzes the removal of oxygen and hydrogen from organic compounds in the form of water. ... In biochemistry, a synthase is an enzyme which catalyzes a synthesis process. ... Adenylate cyclase Adenylate cyclase (EC 4. ... Guanylate cyclase (EC 4. ... In biochemistry, an isomerase is any enzyme that catalyses the interconversion of isomers. ... This list contains a list of EC numbers for the fifth group, EC 5, isomerases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology. ... An enzyme that catalyzes the shifting of a functional group from one position to another within the same molecule. ... In biochemistry, a ligase (from the Latin verb ligāre — to bind or to glue together) is an enzyme that can catalyse the joining of two large molecules by forming a new chemical bond, usually with accompanying hydrolysis of a small chemical group pendant to one of the larger molecules. ... This list contains a list of EC numbers for the sixth group, EC 6, ligases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology. ... It has been suggested that sticky end/blunt end be merged into this article or section. ... An aminoacyl tRNA synthetase (abbreviated aaRs) is an enzyme that catalyzes the binding of a specific amino acid to a tRNA to form an aminoacyl-tRNA. The synthetase hydrolyzes ATP to bind the appropriate amino acid to the 3 hydroxyl of the tRNA molecule. ...

Type I topoisomerase - Type II topoisomerase (gyrase, topoisomerase IV) In biochemistry, an isomerase is any enzyme that catalyses the interconversion of isomers. ... The Enzyme Commission number (EC number) is a numerical classification scheme for enzymes, based on the chemical reactions they catalyze. ... Topoisomerase I solves the problem caused by tension generated by winding/unwinding of DNA. It wraps around DNA and makes a cut permitting the helix to spin. ... Structure of the 42 KDa fragment of the N-terminal of DNA gyrase homologous to all other type IIA topoisomerases. ... Topoisomerases (Type I: EC 5. ... Topoisomerase IV is one of two type-II topoisomerases in bacteria, the other being DNA gyrase. ...

Origin of replication/Ori/Replicon - DNA clamp - Okazaki fragment - Replication fork (Lagging and leading strands) - Single-strand binding protein - Primer - Processivity - Klenow fragment This article or section is in need of attention from an expert on the subject. ... The origin of replication (also called the replication origin) is a unique DNA sequence at which DNA replication is initiated. ... Ori is the DNA sequence that signals for the origin of replication, sometimes refered to simply as origin. ... A replicon is a DNA molecule or RNA molecule, or a region of DNA or RNA that replicates from a single origin of replication. ... The assembled human DNA clamp, a trimer of the protein PCNA. A DNA clamp, also known as a sliding clamp, is a protein fold that serves as a processivity-promoting factor in DNA replication. ... śś¼Wiki markup: {{}} | [] [[]] [[Category:]] #REDIRECT [[]] Cite error 4; Invalid <ref> tag; refs with no name must have content • (templates) Okazaki fragment is a relatively short fragment of DNA (with an RNA primer at the 5 terminus) created on the lagging strand during DNA replication. ... DNA split along the replication fork The replication fork is a structure which forms when DNA is ready to replicate itself. ... In DNA replication, the lagging strand is the DNA strand at the opposite side of the replication fork from the leading strand. ... The leading strand is the DNA strand at the opposite side of the replication fork from the lagging strand. ... Single-strand binding protein, or SSB, binds single stranded regions of DNA to prevent premature reannealing. ... A primer is a nucleic acid strand, or a related molecule that serves as a starting point for DNA replication. ... Processivity is the frequency with which an enzyme dissociates from the template during DNA replication. ... To meet Wikipedias quality standards, this article or section may require cleanup. ...

Pre-replication complex: Helicase (dnaA, dnaB, T7) - Primase (dnaG) - DNA polymerase III holoenzyme (dnaQ) A pre-replication complex is a protein complex that forms at the origin of replication during the initiation step of DNA replication. ... This article or section does not adequately cite its references or sources. ... dnaA is an replication initiation factor which hydrolyzes ATP and promotes the unwinding or melting of DNA at oriC, during DNA replication in prokaryotes. ... dnaB helicase is an enzyme which holds open the replication fork during DNA replication. ... T7 DNA Helicase is a hexameric motor protein that uses energy from dTTP hydrolysis to process unidirectionally along single stranded DNA, separating the two strands as progresses. ... DNA primase is a form of RNA polymerase and a product of the dnaG gene. ... dnaG is a primase which synthesizes RNA primer. ... Pol III can also refer to KNM Pol III, a Norwegian guard vessel from WW2 DNA polymerase III holoenzyme is the primary enzyme complex involved in prokaryotic DNA replication. ... In biology, dnaQ polymerizes the &#949; subunit of the DNA polymerase III holoenzyme. ...

DNA ligase - Telomerase - Topoisomerase It has been suggested that sticky end/blunt end be merged into this article or section. ... Telomerase is an enzyme that adds specific DNA sequence repeats (TTAGGG in all vertebrates) to the 3 (three prime) end of DNA strands in the telomere regions, which are found at the ends of eukaryotic chromosomes. ...