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Encyclopedia > Tosyl
The tosylate group with a generic 'R' group attached
The tosylate group with a generic 'R' group attached

A tosyl group (abbreviated Ts or Tos) combines the toluene and sulfonyl functional groups. The sulfonyl group consists of a hexavalent sulfur atom double bonded to two oxygen atoms and, in the tosylate group, an aromatic ring; an alkyl substituent on the R group forms a sulfonate ester. Thus, the tosylate group is the ester of toluenesulfonic acid. The para orientation illustrated (p-toluenesulfonyl) is most common, and by convention tosyl refers to the p-toluenesulfonate ester. Image File history File links Size of this preview: 800 × 409 pixel Image in higher resolution (1661 × 850 pixel, file size: 13 KB, MIME type: image/png) (All user names refer to en. ... Image File history File links Size of this preview: 800 × 409 pixel Image in higher resolution (1661 × 850 pixel, file size: 13 KB, MIME type: image/png) (All user names refer to en. ... Look up R, r in Wiktionary, the free dictionary. ... ==GROUP== CONTENTS : 1. ... A combine may be: a combine harvester, used in agriculture a combine car, a type of railway car a corporation, syndicate, or zaibatsu: all terms for vast, monopolistic commercial institutions. ... Toluene, also known as methylbenzene or phenylmethane is a clear, water-insoluble liquid with the typical smell of paint thinners, redolent of the sweet smell of the related compound benzene. ... Sulfonyl is an organic radical (or functional group) obtained from an sulfonic acid by the removal of the hydroxyl group. ... In ecology functional groups are collections of organisms based on morphological, physiological, behavioral, biochemical, or environmental responses or on trophic criteria. ... Sulfonyl is an organic radical (or functional group) obtained from an sulfonic acid by the removal of the hydroxyl group. ... ==GROUP== CONTENTS : 1. ... This article is about trains in rail transport. ... Valence, also known as valency or valency number, is a measure of the number of chemical bonds formed by the atoms of a given element. ... General Name, Symbol, Number sulfur, S, 16 Chemical series nonmetals Group, Period, Block 16, 3, p Appearance lemon yellow Atomic mass 32. ... Properties In chemistry and physics, an atom (Greek ἄτομος or átomos meaning indivisible) is the smallest particle still characterizing a chemical element. ... Covalent bonding is a form of chemical bonding characterized by the sharing of one or more pairs of electrons between atoms, in order to produce a mutual attraction, which holds the resultant molecule together. ... 2 (two) is the natural number following 1 and preceding 3. ... General Name, Symbol, Number oxygen, O, 8 Chemical series nonmetals, chalcogens Group, Period, Block 16, 2, p Appearance colorless (gas) very pale blue (liquid) Atomic mass 15. ... Properties In chemistry and physics, an atom (Greek ἄτομος or átomos meaning indivisible) is the smallest particle still characterizing a chemical element. ... An aromatic hydrocarbon (abbreviated as AH), or arene is a hydrocarbon, the molecular structure of which incorporates one or more planar sets of six carbon atoms that are connected by delocalised electrons numbering the same as if they consisted of alternating single and double covalent bonds. ... An alkyl is a univalent radical containing only carbon and hydrogen atoms arranged in a chain. ... In organic chemistry, a substituent is an atom or group of atoms substituted in place of a hydrogen atom on the parent chain of a hydrocarbon. ... Look up R, r in Wiktionary, the free dictionary. ... ==GROUP== CONTENTS : 1. ... A sulfonate anion consists of sulfur double bonded to two oxygens and bonded to an R group and an oxygen anion. ... General formula of a carboxylate ester. ... ==GROUP== CONTENTS : 1. ... General formula of a carboxylate ester. ... p-Toluenesulfonic acid is an organic compound with the formula CH3C6H4SO3H. TsOH, as it is abbreviated, is a white solid that is soluble in water, alcohols, and other polar organic solvents. ... Arene substitution patterns are part of organic chemistry IUPAC nomenclature and pinpoint the position of substituents other than hydrogen in relation to each other on an aromatic hydrocarbon. ... Drawing is one way of making an image: it is the process of making marks on a surface by applying pressure from or moving a tool on the surface. ... Most is a city in the northwest of the Czech Republic, in Ústí nad Labem Region. ... As a noun, common may refer to: An alternate form of commons A common - an area of common land The rapper, Common (formerly known as Common Sense) As an adjective, common may denote: Ordinary or most frequently occurring; prevalent. ... Convention has at least two very distinct but related meanings. ... REFER, EP (EP stands for Empresa Publica, English, Public Enterprise) Portuguese Rail Infrastructure Manager, since 1997. ... General formula of a carboxylate ester. ...


A tosylate ester has only a limited shelf life if it is stored outside of a dessicator as the free tosyl is readily hydrolysed by water in the presence of light. The tosyl group is electron-withdrawing. Hence, it is an excellent leaving group. General formula of a carboxylate ester. ... Limited can refer to: A private limited company by shares, a specific kind of limited company in Commonwealth of Nations commercial law; often used as a suffix (Mycompany, Limited or ); formerly used for all limited companies. ... Shelf is a detail of furniture for storing items. ... For other uses, see Life (disambiguation), Lives (disambiguation) or Living (disambiguation), Living Things (disambiguation). ... Look up Outside in Wiktionary, the free dictionary Things commonly named outside include: Outside — a magazine 1. ... Desiccation is the state of extreme dryness, or the process of extreme drying. ... Look up Free in Wiktionary, the free dictionary. ... Hydrolysis is a chemical reaction or process in which a molecule is split into two parts by reacting with a molecule of water, which has the chemical formula H2O. One of the parts gets an OH- from the water molecule and the other part gets an H+ from the water. ... Impact of a drop of water Water is a chemical substance that is essential to all known forms of life[1]. It covers 71% of Earths surface. ... Presence is the seventh studio album by English rock band Led Zeppelin, released by Swan Song Records on March 31, 1976. ... Prism splitting light Light is electromagnetic radiation with a wavelength that is visible to the eye (visible light) or, in a technical or scientific context, electromagnetic radiation of any wavelength[1]. The elementary particle that defines light is the photon. ... ==GROUP== CONTENTS : 1. ... The Polar effect or electronic effect in chemistry is the effect exerted by a substituent on modifying electrostatic forces operating on a nearby reaction center. ... Excellence - The state of excelling: superiority, presuperiority, pre--eminence; surpassing eminence; surpassing virtue, goodness or merit; Excelsus - sustainable excellence Excellence is outstanding practice in managing organisations and delivering value for customers and other stakeholders (Moullin, 1999) ... A leaving group is an atom or molecule that detaches from an organic molecule, which, after detachment, is called the residual or main part. ...


The tosyl group is a protecting group for alcohols, prepared by combining the alcohol with toluenesulfonyl chloride in an aprotic solvent. Toluenesulfonyl chlorides activate alcohols for nucleophilic attack or elimination (dehydration). ==GROUP== CONTENTS : 1. ... A Protecting group or protective group is introduced into a molecule by chemical modification of a functional group in order to obtain chemoselectivity in a subsequent chemical reaction. ... Functional group of an alcohol molecule. ... Functional group of an alcohol molecule. ... Thionyl chloride (or thionyl dichloride) is an inorganic compound with the formula SOCl2. ... In chemistry any solvent that carries hydrogen attached to oxygen as in a hydroxyl group or nitrogen as in a amine group is called a protic solvent. ... The chloride ion is formed when the element chlorine picks up one electron to form an anion (negatively-charged ion) Cl−. The salts of hydrochloric acid HCl contain chloride ions and are also called chlorides. ... Category: ... Functional group of an alcohol molecule. ... In chemistry, a nucleophile (literally nucleus lover) is a reagent which is attracted to centres of positive charge. ... Elimination is a residence hall game where every player is both the hunter and the hunted. ... Dehydration (hypohydration) is the removal of water (hydro in ancient Greek) from an object. ...


Similarly, the brosyl (Bs) group or brosylate is a p-bromobenzenesulfonyl group with the methyl group of toluene replaced by a bromine atom. Nosyl groups in Nosylates (Ns) are 4-nitrobenzenesulfonyl groups with a nitro group in the para position. Several equivalence relations in mathematics are called similarity. ... In chemistry a methyl-group is a hydrophobic Alkyl functional group which is derived from methane (CH4). ... ==GROUP== CONTENTS : 1. ... Toluene, also known as methylbenzene or phenylmethane is a clear, water-insoluble liquid with the typical smell of paint thinners, redolent of the sweet smell of the related compound benzene. ... General Name, Symbol, Number bromine, Br, 35 Chemical series halogens Group, Period, Block 17, 4, p Appearance gas/liquid: red-brown solid: metallic luster Atomic mass 79. ... Properties In chemistry and physics, an atom (Greek ἄτομος or átomos meaning indivisible) is the smallest particle still characterizing a chemical element. ... ==GROUP== CONTENTS : 1. ... Nitro may refer to: Nitroglycerin, an extremely explosive chemical compound Nitrous, a type of fuel additive for race cars Nitromethane, another type of fuel additive for race cars Glyceryl trinitrate (pharmacology), a medical compound used for the treatment of angina pectoris Nitrogen, especially when used in draught beer Nitrocellulose, an... ==GROUP== CONTENTS : 1. ... Look up para in Wiktionary, the free dictionary. ... Look up position in Wiktionary, the free dictionary. ...


  Results from FactBites:
 
Tosyl - Wikipedia, the free encyclopedia (207 words)
Thus, the tosylate group is the ester of toluenesulfonic acid.
A tosylate ester has only a limited shelf life if it is stored outside of a desicator as the free tosyl is readily broken by light and water.
The tosyl group is a protecting group for alcohols, prepared by combining the alcohol with toluenesulfonyl chloride in an aprotic solvent.
Data Sheet (2221 words)
Bretylium tosylate is indicated in the prophylaxis and therapy of ventricular fibrillation.
Bretylium tosylate is also indicated in the treatment of life-threatening ventricular arrhythmias, such as ventricular tachycardia that have failed to respond to adequate doses of first-line antiarrhythmic agent, such as lignocaine.
Bretylium tosylate is contraindicated in the presence of digitalis induced arrhythmias as initial noradrenaline release caused by bretylium may aggravate digitalis toxicity.
  More results at FactBites »


 

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