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Encyclopedia > Trace amine

Trace amines are endogenous compounds structurally related to classical biogenic amines, such as catecholamines, serotonin and histamine. Trace amines include p-tyramine, β-phenylethylamine, tryptamine, and octopamine, and are found in the nervous systems of animals from insects to mammals. In an economic model, an endogenous change is one that comes from inside the model and is explained by the model itself. ... Catecholamines are chemical compounds derived from the amino acid tyrosine that act as hormones or neurotransmitters. ... Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine neurotransmitter synthesized in serotonergic neurons in the central nervous system (CNS) and enterochromaffin cells in the gastrointestinal tract. ... This article or section does not cite its references or sources. ... Tryptamine (3-(2-aminoethyl)indole) is a monoamine compound that is widespread in nature. ... Octopamine (4-(2-amino-1-hydroxy-ethyl)phenol) is a biogenic amine which is closely related to noradrenaline. ...


Trace amines overlap substantialy with classical biogenic amines neurotransmitters regarding to chemical properties, synthesis, and breakdown; trace amines commonly colocalize in neurons with these neurotransmitters. Chemical structure of D-Aspartic Acid, a common Amino Acid neurotransmitter. ...


Psychiatric disorders such as depression and schizophrenia have been linked to irregular levels of trace amines. Clinical depression (also called major depressive disorder, or sometimes unipolar when compared with bipolar disorder) is a state of intense sadness, melancholia or despair that has advanced to the point of being disruptive to an individuals social functioning and/or activities of daily living. ...


See also

  • Trace amine-associated receptor


 

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