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Transferrin is a plasma protein for iron ion delivery. When a transferrin protein loaded with iron encounters a transferrin receptor on the surface of a cell, it binds to it and is consequently transported into the cell in a vesicle. The cell will acidify the vesicle, causing transferrin to release its iron ions. Each transferrin molecule has the ability to carry two iron ions in the ferric form (Fe3+). Look up plasma in Wiktionary, the free dictionary. ...
A representation of the 3D structure of myoglobin, showing coloured alpha helices. ...
General Name, Symbol, Number iron, Fe, 26 Chemical series transition metals Group, Period, Block 8, 4, d Appearance lustrous metallic with a grayish tinge Atomic mass 55. ...
// An ion is an atom or a group of atoms (a chemical substance), or subatomic particle, with a net electric charge. ...
Cells in culture, stained for keratin (red) and DNA (green). ...
In cell biology, a vesicle is a relatively small and enclosed compartment, separated from the cytosol by at least one lipid bilayer. ...
Ferric is a term used for the iron with the oxidation number +3. ...
The gene coding for transferrin in humans is located in chromosome band 3q21. This stylistic schematic diagram shows a gene in relation to the double helix structure of DNA and to a chromosome (right). ...
Figure 1: Chromosome. ...
Transferrin levels may be checked in iron deficiency, hemochromatosis and other iron overload disorders. Iron deficiency can refer to: Iron deficiency (plant disorder) Iron deficiency (medicine) This is a disambiguation page — a navigational aid which lists other pages that might otherwise share the same title. ...
Haemochromatosis, also spelled hemochromatosis, is a hereditary disease characterized by improper processing by the body of dietary iron which causes iron to accumulate in a number of body tissues, eventually causing organ dysfunction. ...
In medicine, iron overload disorders are diseases caused by the accumulation of iron in the body. ...
Transferrin are also associated with the innate immune system. Transferrin are found in the mucosa and bind iron, thus creating an environment low in free iron, where few bacteria are able to survive. The mucous membranes (or mucosa) are linings of ectodermic origin, covered in epithelium, that line various body cavities and internal organs. ...
Note that the metal binding properties of transferrin have a great infulance on the biochemistry of plutonium in humans. General Name, Symbol, Number plutonium, Pu, 94 Chemical series actinides Group, Period, Block n/a, 7, f Appearance silvery white Atomic mass (244) g/mol Electron configuration [Rn] 5f6 7s2 Electrons per shell 2, 8, 18, 32, 24, 8, 2 Physical properties Phase solid Density (near r. ...
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