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Encyclopedia > United Devices Cancer Research Project
UD Agent
UD Agent

The United Devices Cancer Research Project, is one of several distributed computing projects that have been operated on the grid.org website by United Devices. Download high resolution version (916x629, 366 KB)United Devices Agent This is a screenshot of copyrighted computer software. ... Download high resolution version (916x629, 366 KB)United Devices Agent This is a screenshot of copyrighted computer software. ... In computer science, distributed computing studies the coordinated use of physically distributed computers. ... United Devices, Inc. ...

Contents


Cancer Research Project

The United Devices Cancer Research Project which began in 2001, is seeking possible drugs for the treatment of cancer using distributed computer power. 140,000 users in the United States and 158,000 in Europe participate in the project. 2001: A Space Odyssey. ... When normal cells are damaged or old they undergo apoptosis; cancer cells, however, avoid apoptosis. ... In computer science, distributed computing studies the coordinated use of physically distributed computers. ... Europe forms the westernmost part of Eurasia. ...


The projects is an alliance of several companies and organisations

United Devices released the cancer research screensaver under the principle of utilising spare computing power. The program, which can also be set to run continually, uses "virtual screening" to find possible interactions between molecules and target proteins, i.e. a drug. These molecules (ligands) are sent to the host computer's UD Agent. When these molecules dock successfully with a target protein this interaction is scored for further investigation. United Devices, Inc. ... The National Foundation for Cancer Research was founded in 1973 as a non-profit organization under U.S. tax code 501(c)(3). ... The University of Oxford, located in the city of Oxford, England, is the oldest university in the English-speaking world. ... Intel Corporation (NASDAQ: INTC) (HKSE: 4335) (founded 1968) is a U.S.-based multinational corporation that is best known for designing and manufacturing microprocessors and specialized integrated circuits. ... Microsoft Corporation (NASDAQ: MSFT) (HKSE: 4338) is the worlds largest software company, with 2005 global annual sales of 40 billion US dollars and more than 55,000 employees in 85 countries and regions. ... A screensaver is a computer program originally designed to conserve the image quality of computer displays by blanking the screen or filling them with moving images or patterns when the computers are not in use. ... In chemistry, a ligand is an atom, ion or functional group that is bonded to one or more central atoms or ions, usually metals generally through coordinate covalent bond. ...


Phase 1 has been completed and Phase 2 is underway. In Phase 1, over 3 billion drug-like molecules were tested against 12 proteins which are known as suitable targets for anti-cancer drugs. It used the "THINK" software for the simulation of the molecular interactions.


Phase 2, using the "LigandFit" software developed by Accelrys to model interactions, seeks to refine the Phase 1 data to produce a more manageable list of drug candidates for testing which will require experimental collaborators including some from industry.


Human Proteome Folding Project

The Human Proteome Folding Project was announced on November 16, 2004 as a joint partnership between United Devices and IBM. In order to accommodate the large number of expected participants, the project would be operated simultaneously on both the grid.org servers and on IBM's World Community Grid servers. November 16 is the 320th day of the year (321st in leap years) in the Gregorian Calendar, with 45 days remaining. ... 2004 (MMIV) was a leap year starting on Thursday of the Gregorian calendar. ... The World Community Grid is an effort to create the worlds largest public computing grid to tackle projects that benefit humanity. ...


It makes use of the "Rosetta" software to predict the structure of human proteins, in order to help predict the function of proteins. This information may someday be used to help cure a variety of diseases and genetic defects.


Past projects

Anthrax Project

The Anthrax Research Project was a part of the United Devices "Patriot Grid" initiative to fight biological terrorism. It made use of the "LigandFit" software (that had already been used by phase 2 of the Cancer Research project), but with a specialized set of target moleculated that targeted the advanced stages of anthrax bacterial infection.


The project was operated from January 22, 2002 until February 14, 2002, after a total of 3.57 billion molecules had finished screening. The results of the research project were transmitted to biological scientists in order to finish the screening of the computational simulations.[1] January 22 is the 22nd day of the year in the Gregorian Calendar. ... 2002 (MMII) is a common year starting on Tuesday of the Gregorian calendar. ... February 14 is the 45th day of the year in the Gregorian Calendar. ... 2002 (MMII) is a common year starting on Tuesday of the Gregorian calendar. ...


The partners of the project included Oxford University. The University of Oxford, located in the city of Oxford in England, is the oldest university in the English-speaking world. ...


Smallpox Project

The Smallpox Research Grid was a part of United Devices "Patriot Grid" initiative to fight biological terrorism. It made use of the "LigandFit" software (that had already been used by phase 2 of the Cancer Research project), but with a specialized set of target molecules that targeted the smallpox virus. Smallpox (also known by the Latin names Variola or Variola vera) is a highly contagious disease unique to humans. ...


The partners of the project included University of Oxford, the University of Western Ontario, Memorial Sloan Kettering Cancer Research Center, Essex University, Evotec OAI, Accelrys, and IBM. The University of Oxford, located in the city of Oxford, England, is the oldest university in the English-speaking world. ... The University of Western Ontario is a public, non-denominational university located in London, Ontario, Canada. ... Introduction The University of Essex is a Campus university based at Wivenhoe Park on the outskirts of Colchester (the oldest recorded town in Britain) in the English county of Essex, less than a mile from the town of Wivenhoe. ... International Business Machines Corporation (IBM, or colloquially, Big Blue) NYSE: IBM (incorporated June 15, 1911, in operation since 1888) is headquartered in Armonk, NY, USA. The company manufactures and sells computer hardware, software, and services. ...


HMMER Project

The HMMER Genetic Research project made use of the Hidden Markov model to search for patterns in genetic DNA sequences. [2] A hidden Markov model (HMM) is a statistical model where the system being modelled is assumed to be a Markov process with unknown parameters, and the challenge is to determine the hidden parameters, from the observable parameters, based on this assumption. ...


Webload Project

The Web Performance Testing project was operated as a commercial opportunity with select web hosting providers in order to help them test the scalability of their server infrastructures under periods of high-demand. [3] Web hosting is a service that provides individuals, organizations and users with online systems for storing information, images, video, or any content accessible via the Web. ...


See also

A list of distributed computing projects. ...

External links

  • BBC News report
  • Grid.org
    • Download cancer project
  • The National Foundation for Cancer Research
  • United Devices Inc.
  • Department of Chemistry at the University of Oxford


 

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