Ureaplasma urealyticum is a bacterium belonging to the family Mycoplasmataceae. Its type strain is T960.
This microorganism is part of the normal genital flora of both men and women. It is found in about 70% of sexually active humans. It can also cause disease, including non-specific urethritis (NSU), infertility, chorioamnioitis, stillbirth, premature birth, and, in the perinatal period, pneumonia or meningitis.
There are six recognised Ureaplasma species, They have a G+C content of 27 - 30 mol%, and a genome size ranging between 0.76 - 1.17 Gbp, and cholesterol is required for growth. A defining characteristic of the genera is that they perform urea hydrolysis.
It is now recommended that some strains originally classified as Ureaplasma urealyticum should be treated as a new species, U. parvum.
Gnarpe and Friberg isolated ureaplasma from the cervix of 85% of infertile women and from the semen of 95% of their partners but from only 23% of control females and 26% of control males [12].
Investigators concluded that ureaplasma was not associated with primary infertility and that although doxycycline eradicated the infection, doxycycline was of no benefit in the treatment of primary infertility of unknown cause [22].
The correlation of Ureaplasmaurealyticum infection with infertility.
Ureaplasmaurealyticum respiratory tract colonization is associated with an increase in interleukin 1-beta and tumor necrosis factor alpha relative to interleukin 6 in tracheal aspirates of preterm infants.
Prevalence and antibiotic susceptibility of Ureaplasmaurealyticum in Malaysian neonates with respiratory distress.
Detection of Ureaplasmaurealyticum by polymerase chain reaction in the urogenital tract of adults, in amniotic fluid, and in the respiratory tract of newborns.
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