Uremia is a toxic condition resulting from renal failure, when kidney function is compromised and urea, a waste product normally excreted in the urine, is retained in the blood. Uremia can lead to disturbances in the platelets and hypersomnia, among other effects. Renal failure is the condition where the kidneys fail to function properly. ... Human kidneys viewed from behind with spine removed The kidneys are bean-shaped excretory organs in vertebrates. ... Urea is an organic compound of carbon, nitrogen, oxygen and hydrogen, with the formula CON2H4 or (NH2)2CO. Urea is also known as carbamide, especially in the recommended International Non-proprietary Names (rINN) in use in Europe. ... To meet Wikipedias quality standards, this article or section may require cleanup. ... Human blood smear: a - erythrocytes; b - neutrophil; c - eosinophil; d - lymphocyte. ... A 250 ml bag of newly collected platelets. ... Hypersomnia is an excessive amount of sleepiness, resulting in an inability to stay awake. ...
Azotemia is another word that refers to high levels of urea, but is used primarily when the abnormality can be measured chemically but is not yet so severe as to produce symptoms. Uremia takes a long time to develop. Azotemia is a medical condition characterized by abnormal levels of urea, creatinine, various body waste compounds, and other nitrogen-rich compounds in the blood as a result of insufficient filtering of the blood by the kidneys. ...
Besides renal failure, the level of urea in the blood can also be increased by: Renal failure is the condition where the kidneys fail to function properly. ...
increased production of urea in the liver, due to:
high protein diet
increased protein breakdown (surgery, infection, trauma, cancer)
Uremia can be caused by NSAIDs (nonsteroid anti-inflammatory drugs), especially in older patients treated primarily with ibuprofen for arthritis.
Some of the early signs of uremia are lethargy, mental depression, loss of appetite, and edema; later symptoms include diarrhea, anemia, convulsions, coma, and a gray-brown coloration.
Treatment of uremia, which is directed at the underlying kidney disease, is usually with dialysis and renal transplantation.
Uremia is a toxic condition resulting from renal failure, when kidney function is compromised and urea, a waste product normally excreted in the urine, is retained in the blood.
Uremia can lead to disturbances in the platelets and hypersomnia, among other effects.
Azotemia is another word that refers to high levels of urea, but is used primarily when the abnormality can be measured chemically but is not yet so severe as to produce symptoms.