The calcitriol receptor, also known as the Vitamin D receptor (VDR) is a member of the steroid hormone family of receptors. Upon activation by vitamin D, the VDR forms a heterodimer with the retinoid-X receptor and binds to hormone response elements on DNA resulting in expression or transrepression of specific geneproducts. Vitamin D is a fat soluble vitamin that contributes to the maintenance of normal levels of calcium and phosphorus in the bloodstream. ... Steroid hormones are steroids which act as hormones. ... The general structure of a section of DNA Deoxyribonucleic acid (DNA) is a nucleic acid —usually in the form of a double helix— that contains the genetic instructions specifying the biological development of all cellular forms of life, and most viruses. ... Expression may refer to: (in the vernacular) the act or particular way of expressing something (including an emotion through a facial expression or configuration) (in mathematics) a mathematical expression (in computing) a programming language expression (in computing) a vector graphics software Microsoft Expression (in genetics) the effect produced by a... This stylistic schematic diagram shows a gene in relation to the double helix structure of DNA and to a chromosome (right). ...

Glucocorticoids are known to decrease expression of VDR which is expressed in most tissues of the body. Its most well known function is the regulation of intestinal transport of calcium. Glucocorticoids are a class of steroid hormones characterised by an ability to bind with the cortisol receptor and trigger similar effects. ... The intestine is the portion of the alimentary canal extending from the stomach to the anus and, in humans and other mammals, consists of two segments, the small intestine and the large intestine. ... General Name, Symbol, Number calcium, Ca, 20 Chemical series alkaline earth metals Group, Period, Block 2, 4, s Appearance silvery white Atomic mass 40. ...