Wilms tumor is a neoplasm of the kidneys that typically occurs in children. It is eponymously named after Dr Max Wilms (http://www.whonamedit.com/doctor.cfm/2109.html), a German surgeon (1867-1918). It is also known as a nephroblastoma.
A triphasic nephroblastoma comprises three elements
The mesenchymal component may include cells showing rhabdomyoid differentiation. The rhabdomyoid component may itself show features of malignancy (rhabdomyosarcomatous Wilms).
Wilms tumor may be sporadic or familial. Predisposition to this neoplasm forms part of some syndromes.
Wilmstumor, named after the German surgeon Dr. Carl Max Wilhelm Wilms, is the commonest form of renal cancer in children.
The most common manifestation of Wilmstumor is that of a lump in the belly (abdominal mass), often found by either parents or relatives while bathing or dressing the child.
The tumor was biopsied (except for fine needle aspiration), or there was spillage of tumor before or during surgery that is confined to the flank, and does not involve the peritoneal surface.
WAGR is an abbreviation for Wilmstumor, aniridia, genitourinary tract abnormalities, and mental retardation.
Tumor cells that are not anaplastic are said to be Wilmstumor of favorable histology.
While 90 percent of all kidney cancers in children are Wilmstumor, the remaining 10 percent are clear cell sarcoma of the kidney, rhabdoid tumor of the kidney, or renal cell carcinoma.
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