Wolf Island is an unincorporated community in eastern Mississippi County, Missouri. It is located on Missouri State Highway 77 about nine miles east of East Prairie. The community was founded in 1792 and is named for Wolf Island in the Mississippi River which is part of Kentucky. The Eastern Timber Wolf was native to this region, but has since been extirpated. Mississippi County is a county located in the state of Missouri. ... Missouri State Highway 77 is a highway in southeastern Missouri. ... East Prairie is a city located in Mississippi County, Missouri. ... 1792 was a leap year starting on Sunday (see link for calendar). ... This article is about the river in the United States. ... Official language(s) English Capital Frankfort Largest city Louisville Area  - Total  - Width  - Length  - % water  - Latitude  - Longitude Ranked 37th 104,749 km² 225 km 610 km 1. ... Trinomial name Canis lupus lycaon Schreber, 1775 The Eastern Timber Wolf (Canis lupus lycaon) is a subspecies of the Gray Wolf and is a native species to North America. ... Extirpation is the localized extinction of a species. ...