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Encyclopedia > Mammillary body
Brain: Mammillary body
The hypophysis cerebri in position. Shown in sagittal section. (Label "corpus mamillare" at right.)
Coronal section of brain through intermediate mass of third ventricle. (Label "corpus mamillare" at bottom.)
Latin corpus mamillare
Gray's subject #188 813
Part of Midbrain
System Limbic
Components medial mammillary nucleus
lateral mammillary nucleus
Acronym(s) mmb
NeuroNames hier-395
MeSH Mamillary+Bodies

The mammillary bodies (mamillary bodies) are a pair of small round bodies, located on the undersurface of the brain, that form part of the limbic system. They are located at the ends of the anterior arches of the fornix. They consist of two groups of nuclei, the medial mammillary nuclei and the lateral mammillary nuclei.
Neuroanatomists have often categorized the mammillary bodies as part of the hypothalamus.[1] Image File history File links Gray1180. ... Image File history File links Gray718. ... For other uses, see Latins and Latin (disambiguation). ... In biological anatomy, the mesencephalon (or midbrain) is the middle of three vesicles that arise from the neural tube that forms the brain of developing animals. ... The limbic system is a historically defined set of brain structures that support a variety of functions including emotion and memory. ... NeuroNames is a system of nomenclature for the brain and related structures. ... Medical Subject Headings (MeSH) is a huge controlled vocabulary (or metadata system) for the purpose of indexing journal articles and books in the life sciences. ... For other uses, see Brain (disambiguation). ... The limbic system is a historically defined set of brain structures that support a variety of functions including emotion and memory. ... In zootomy, several terms are used to describe the location of organs and other structures in the body of bilateral animals. ... The fornix is also the name of part of the cervix (fornix vaginae). ... The hypothalamus links the nervous system to the endocrine system via the pituitary gland (hypophysis). ...

Contents

Connections

They are connected to other parts of the brain (as shown in the schematic, below left), and act as a relay for impulses coming from the amygdalae and hippocampi, via the mamillo-thalamic tract to the thalamus. This article is about part of the human brain. ... For other uses, see Hippocampus (disambiguation). ... The mammillothalamic fasciculus (mammillothalamic tract, thalamomammillary fasciculus, bundle of Vicq d’Azyr) arises from cells in both the medial and lateral nuclei of the mammillary body and by fibers that are directly continued from the fornix. ... The thalamus (from Greek θάλαμος = bedroom, chamber, IPA= /ˈθæləməs/) is a pair and symmetric part of the brain. ...


This circuit, from amygdalae to mamillary bodies, and then on to the thalamus, is part of the larger 'Papez circuit'. Papez Circuit Described by James Papez in 1937, the Papez circuit of the brain is one of the major pathways of the limbic system. ...


Function

They are involved with the processing of recognition memory, along with the anterior and dorsomedial nuclei in the thalamus.


Pathology

The mammillary bodies are parts of the brain known to be significantly damaged by alcohol intoxication, especially by chronic alcohol abuse and associated deficiency of thiamine. Researchers, in 1998, also noted visible abnormalities in the mammillary bodies of individuals with autism.[2] Ethyl alcohol, also known as ethanol or grain alcohol, is a flammable, colorless chemical compound, one of the alcohols that is most often found in alcoholic beverages. ... ... This article needs cleanup. ... For the similarly spelled nucleic acid, see Thymine Thiamine or thiamin, also known as vitamin B1, is one of the B vitamins. ... Year 1998 (MCMXCVIII) was a common year starting on Thursday (link will display full 1998 Gregorian calendar). ... Autism is a brain development disorder characterized by impairments in social interaction and communication, and restricted and repetitive behavior, all exhibited before a child is three years old. ...


Damage to the mammillary bodies due to thiamine deficiency is implied in pathogenesis of Wernicke-Korsakoff syndrome. Symptoms include impaired memory, also called anterograde amnesia, suggesting that the mammillary bodies may be important for memory. Lesions of the medial dorsal and anterior nuclei of the thalami and lesions of the mammillary bodies are commonly involved in amnesic syndromes in humans.[3] For the similarly spelled nucleic acid, see Thymine Thiamine or thiamin, also known as vitamin B1, is one of the B vitamins. ... Wernicke-Korsakoff syndrome is a combination of Korsakoffs syndrome, which is characterized by confusion, severe anterograde and retrograde amnesia and confabulation; and Wernickes encephalopathy, which is characterized by nystagmus, ophthalmoplegia, coma and, if untreated, death. ... For other uses, see Memory (disambiguation). ... Anterograde amnesia is a form of amnesia, or memory loss, in which new events are not transferred from short-term memory to long-term memory. ... For other uses, see Amnesia (disambiguation). ...


Additional images

References

  1. ^ M.B. Carpenter and J. Sutin: Human Neuroanatomy (8th edition) 1983
  2. ^ - "The Auditory System: Anatomy and Maturation" at www.conradsimon.org
  3. ^ Duprez T, Serieh B, Raftopoulos C (2005). "Absence of memory dysfunction after bilateral mammillary body and mammillothalamic tract electrode implantation: preliminary experience in three patients". AJNR. American journal of neuroradiology 26 (1): 195-7; author reply 197-8. PMID 15661728. 

External links

Median Eminence The median eminence is part of the inferior boundary for the hypothalamus. ... The tuber cinereum is a hollow madda of gray substance situated between the corpora mammillaria behind, and the optic chiasma in front. ... The Medial forebrain bundle is a portion of the brain between the ventral tegmentum and the hypothalamus. ... The subthalamus, or ventral thalamus, is part of the diencephalon. ... Coronal slices of human brain showing the basal ganglia, globus pallidus: external segment (GPe), subthalamic nucleus (STN), globus pallidus: internal segment (GPi), and substantia nigra (SN). ... The zona incerta is a small region of gray matter that is part of the subthalamus. ... The thalamic fasciculus is a component of the subthalamus. ... The lenticular fasciculus is a component of the subthalamus. ... The superior layer of the substantia innominata of Meynert is named the ansa lenticularis (ansa lentiformis in older texts), and its fibers, derived from the medullary lamina of the lentiform nucleus, pass medially to end in the thalamus and subthalamic region, while others are said to end in the tegmentum... Visual pathway with optic chiasm circled The optic chiasm (from the Greek χλαζειν to mark with an X, after the letter Χ chi) is the part of the brain where the optic nerves partially cross, those parts of the right eye which see things on the right side being connected to the... The Subfornical organ is one of the circumventricular organs of the brain and is involved in thirst-regulation. ... The mammillothalamic fasciculus (mammillothalamic tract, thalamomammillary fasciculus, bundle of Vicq d’Azyr) arises from cells in both the medial and lateral nuclei of the mammillary body and by fibers that are directly continued from the fornix. ...

  Results from FactBites:
 
Mammillary body - Wikipedia, the free encyclopedia (248 words)
The mammillary bodies are a pair of small round bodies in the brain forming part of the limbic system.
The mammillary bodies are parts of the brain known to be significantly damaged by alcohol intoxication, especially by chronic alcohol abuse and associated deficiency of thiamine.
Damage to the mammillary bodies due to thiamine deficiency is implied in pathogenesis of Wernicke-Korsakoff syndrome.
Evidence of a Spatial Encoding Deficit in Rats with Lesions of the Mammillary Bodies or Mammillothalamic Tract -- Vann ... (6983 words)
Allen GV, Hopkins DA (1990) Topography and synaptology of mammillary body projections to the mesencephalon and pons in the rat.
Kocsis B, Vertes RP (1994) Characterization of neurons of the supramammillary nucleus and mammillary body that discharge rhythmically with hippocampal theta in the rat.
Seki M, Zyo K (1984) Anterior thalamic afferents from the mammillary body and the limbic cortex in the rat.
  More results at FactBites »


 

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