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Robert Burns Woodward (April 10, 1917–July 8, 1979) was an American organic chemist. He made many important contributions to modern organic chemistry, especially in the synthesis and structure determination of complex natural products, and worked closely with Roald Hoffmann on theoretical studies of chemical reactions. Woodward won the Nobel Prize in Chemistry in 1965. April 10 is the 100th day of the year in the Gregorian calendar (101st in leap years). ...
1917 (MCMXVII) was a common year starting on Monday of the Gregorian calendar (see link for calendar) or a common year starting on Tuesday of the 13-day slower Julian calendar. ...
July 8 is the 189th day of the year (190th in leap years) in the Gregorian Calendar, with 176 days remaining. ...
This page refers to the year 1979. ...
Organic chemistry is a specific discipline within the subject of chemistry. ...
Roald Hoffmann (born July 18, 1937 as Roald Safran --- Hoffmann is the surname of his stepfather) is an American theoretical chemist of Polish-Jewish origin. ...
This is a list of Nobel Prize laureates in Chemistry from 1901 to the present day. ...
Early life and education
Woodward was born in Boston, Massachusetts, the son of Arthur Woodward (an immigrant from England) and Margaret Woodward, nee Burns (an immigrant from Scotland, born in Glasgow). Nickname: City on a Hill, Beantown, The Hub of the Universe (The State House, according to Oliver Wendell Holmes, is the hub of the Solar System), Athens of America Location in Massachusetts Counties Suffolk County Mayor Thomas Menino (D) Area - City 232. ...
Motto: (French for God and my right) Anthem: Multiple unofficial anthems Capital London Largest city London Official language(s) English (de facto) Government Constitutional monarchy - Queen Queen Elizabeth II - Prime Minister Tony Blair MP Unification - by Athelstan AD 927 Area - Total 130,395 km² (1st in UK) 50,346 sq...
Motto: (Latin for No one provokes me with impunity)1 Anthem: Multiple unofficial anthems Capital Edinburgh Largest city Glasgow Official language(s) English, Gaelic, Scots2 Government Constitutional monarchy - Queen of the UK Queen Elizabeth II - Prime Minister of the UK Tony Blair MP - First Minister Jack McConnell MSP Unification - by...
For other uses, see Glasgow (disambiguation). ...
From a very early age, Woodward was attracted to chemistry and engaged in private study while he attended the public primary and secondary schools of Quincy, Massachusetts. By the time he entered high school, he had already managed to perform most of the experiments in Paul Gatterman's then widely used textbook of experimental organic chemistry. In 1928, Woodward contacted the Consul-General of the German consulate in Boston, and through him, managed to obtain copies of a few original papers published in German journals. Later, in his Cope lecture, he recalled how he had been fascinated when, among these papers, he chanced upon Diels and Alder's original communication about the Diels-Alder reaction. Throughout his career, Woodward was to repeatedly and powerfully use and investigate this reaction, both in theoretical and experimental ways. In 1933, he entered the Massachusetts Institute of Technology (MIT), but neglected his formal studies badly enough to be expelled the next year. MIT readmitted him in 1935, and by 1936 he had received the Bachelor of Science degree. Only one year later, MIT awarded him the doctorate, when his classmates were still graduating with their bachelor's degrees. Woodward's doctoral work involved investigations related to the synthesis of the female sex hormone estrone. After a short postdoctoral stint at the University of Illinois, he took a Junior Fellowship at Harvard University from 1937 to 1938, and remained at Harvard in various capacities for the rest of his life. In the 1960s, Woodward was named Donner Professor of Science, a title that freed him from teaching formal courses so that he could devote his entire time to research. Chemistry (from the Greek word Ïημεία (chemeia) meaning cast together or pour together) is the science of matter at the atomic to molecular scale, dealing primarily with collections of atoms (such as molecules, crystals, and metals). ...
Settled: 1625 â Incorporated: 1792 Zip Code(s): 02169, 02170, 02171 â Area Code(s): 617 / 857 Location Location in Massachusetts Government County Norfolk County Form of Government Mayor-council city Mayor William J. Phelan Geography Area Total 26. ...
The Massachusetts Institute of Technology, or MIT, is a private research university located in the city of Cambridge, Massachusetts, USA. Its mission and culture are guided by an emphasis on teaching and research grounded in practical applications of science and technology. ...
A Bachelor of Science (B.S., B.Sc. ...
Structural formula of estrone Estrone is an estrogenic hormone secreted by the ovary. ...
Harvard redirects here. ...
Early work The first major contribution of Woodward's career in the early 1940s was a series of papers describing the application of ultraviolet spectroscopy in the elucidation of the structure of natural products. Woodward collected together a large amount of empirical data, and then devised a series of rules later called the Woodward rules, which could be applied to finding out the structures of new natural substances, as well as non-natural synthesized molecules. The expedient use of newly developed instrumental techniques was a characteristic Woodward exemplified throughout his career, and it marked a radical change from the extremely tedious and long chemical methods of structural elucidation that had been used until then. Ultraviolet (UV) light is electromagnetic radiation with a wavelength shorter than that of visible light, but longer than soft X-rays. ...
Extremely high resolution spectrum of the Sun showing thousands of elemental absorption lines (fraunhofer lines) Spectroscopy is the study of spectra, that is, the dependence of physical quantities on frequency. ...
In 1944, with his post doctoral researcher, William von Doering, Woodward completed the synthesis of the alkaloid quinine, used to treat malaria. Although the synthesis was publicized as a breakthrough in procuring the hard to get medicinal compound from Japanese occupied southeast Asia, in reality it was too long and tedious to adopt on a practical scale. Nevertheless it was a landmark for chemical synthesis. Woodward's particular insight in this synthesis was to realise that the German chemist Paul Rabe had converted a precursor of quinine called quinotoxine to quinine in 1905. Hence, a synthesis of quinotoxine (which Woodward actually synthesized)) would be tantamount to synthesizing quinine. When Woodward accomplished this feat, organic synthesis was still largely a matter of trial and error, and nobody thought that such complex structures could actually be constructed. Woodward showed that organic synthesis could be made into a rational science, and that synthesis could be aided by well-established principles of reactivity and structure. This synthesis was the first one in a series of exceedingly complicated and elegant syntheses that he would undertake. Diagram of Ephedrine An alkaloid is a nitrogenous organic molecule that has a pharmacological effect on humans and animals. ...
Quinine, is a natural white crystalline alkaloid having antipyretic, anti-malarial with analgesic and anti-inflammatory properties and a bitter taste. ...
Malaria (from Medieval Italian: mala aria â bad air; formerly called ague or marsh fever) is an infectious disease that is widespread in many tropical and subtropical regions. ...
Later work and its impact Culminating in the 1930s, the British chemists Christopher Ingold and Robert Robinson among others had investigated the mechanisms of organic reactions, and had come up with empirical rules which could predict reactivity of organic molecules. Woodward was perhaps the first synthetic organic chemist who used these ideas as a predictive framework in synthesis. Woodward's style was the inspiration for the work of hundreds of successive synthetic chemists who synthesized medicinally important and structurally complex natural products. Sir Christopher Kelk Ingold (1893-1970) was a British chemist. ...
Sir Robert Robinson (1886 - 1975). ...
Organic syntheses and Nobel Prize During the late 1940s, Woodward synthesized many complex natural products including quinine, cholesterol, cortisone, strychnine, lysergic acid, reserpine, chlorophyll, cephalosporin, and colchicine. With these, Woodward opened up a new era of synthesis, sometimes called the 'Woodwardian era' in which he showed that natural products could be synthesized by careful applications of the principles of physical organic chemistry, and by meticulous planning. Quinine, is a natural white crystalline alkaloid having antipyretic, anti-malarial with analgesic and anti-inflammatory properties and a bitter taste. ...
Cholesterol is a sterol (a combination steroid and alcohol) and a lipid found in the cell membranes of all body tissues, and transported in the blood plasma of all animals. ...
Cortisone (IPA:ËkôrtÉËsÅn) is a steroid hormone. ...
Strychnine (pronounced (British) or (U.S.)) is a very toxic (LD50 = 1 mg/kg), colourless crystalline alkaloid used as a pesticide, particularly for killing small vertebrates such as rodents. ...
Lysergic acid, also known as D-lysergic acid and (+)-lysergic acid, is a precursor for a wide range of ergoline alkaloids that are produced by the ergot fungus and some plants. ...
Reserpine is an indole alkaloid antipsychotic and antihypertensive drug known to irreversibly bind to storage vesicles of neurotransmitters such as dopamine, norepinephrine, and serotonin. ...
Chlorophyll is a green photosynthetic pigment found in plants, algae, and cyanobacteria. ...
The cephalosporins, are a class of β-lactam antibiotics. ...
Colchicine is a highly poisonous alkaloid, originally extracted from plants of the genus Colchicum (Autumn crocus, also known as the Meadow saffron). Originally used to treat rheumatic complaints and especially gout, it was also prescribed for its cathartic and emetic effects. ...
Many of Woodward's syntheses were described as spectacular by his colleagues and before he did them, it was thought by some that it would be impossible to create these substances in the lab. Woodward's syntheses were also described as having an element of art in them, and since then, synthetic chemists have always looked for elegance as well as utility in synthesis. His work also involved the exhaustive use of the then newly developed techniques of infrared spectroscopy and later, nuclear magnetic resonance spectroscopy. Another important feature of Woodward's syntheses was their attention to stereochemistry or the particular configuration of molecules in three dimensional space. Most natural products of medicinal importance are effective, for example as drugs, only when they possess a specific stereochemistry. This creates the demand for 'stereospecific synthesis', producing a compound with a defined stereochemistry. While today a typical synthetic route routinely involves such a procedure, Woodward was a pioneer in showing how, with exhaustive and rational planning, one could conduct reactions that were stereospecific. Many of his syntheses involved forcing a molecule into a certain configuration by installing rigid structural elements in it, another tactic that has become standard today. In this regard, especially his syntheses of reserpine and strychnine were landmarks. IR spectrum of a thin film of liquid ethanol. ...
Pacific Northwest National Laboratorys high magnetic field (800 MHz, 18. ...
Extremely high resolution spectrum of the Sun showing thousands of elemental absorption lines (fraunhofer lines) Spectroscopy is the study of spectra, that is, the dependence of physical quantities on frequency. ...
The different types of isomers. ...
Reserpine is an indole alkaloid antipsychotic and antihypertensive drug known to irreversibly bind to storage vesicles of neurotransmitters such as dopamine, norepinephrine, and serotonin. ...
Strychnine (pronounced (British) or (U.S.)) is a very toxic (LD50 = 1 mg/kg), colourless crystalline alkaloid used as a pesticide, particularly for killing small vertebrates such as rodents. ...
Woodward also applied the technique of infrared spectroscopy and chemical degradation to determine the structures of complicated molecules. Notable among these structure determinations were santonic acid, strychnine, magnamycin and terramycin. During the war years, Woodward also proposed the correct structure of penicillin as a beta-lactam, as opposed to the thiazolidine-oxazolone structure proposed by Robert Robinson, the then leading organic chemist of his generation. About terramycin, Woodward's colleague and Nobel Laureate Derek Barton said: IR spectrum of a thin film of liquid ethanol. ...
Strychnine (pronounced (British) or (U.S.)) is a very toxic (LD50 = 1 mg/kg), colourless crystalline alkaloid used as a pesticide, particularly for killing small vertebrates such as rodents. ...
Tetracycline is a broad-spectrum antibiotic produced by the streptomyces bacterium, indicated for use against many bacterial infections. ...
Penicillin nucleus Penicillin (sometimes abbreviated PCN) refers to a group of β-lactam antibiotics used in the treatment of bacterial infections caused by susceptible, usually Gram-positive, organisms. ...
A lactam (the noun is a grammatical blend from lactone + amide) is a cyclic amide. ...
Thiazolidine is a heterocycle. ...
Sir Robert Robinson (1886 - 1975). ...
Sir Derek Harold Richard Barton was a British physical chemist and Nobel Prize Laureate. ...
- The most brilliant analysis ever done on a structural puzzle was surely the solution (1953) of the terramycin problem. It was a problem of great industrial importance, and hence many able chemists had performed an enormous amount of work trying to determine the structure. There seemed to be too much data to resolve the problem, because a significant number of observations, although experimentally correct, were very misleading. Woodward took a large piece of cardboard, wrote on it all the facts and, by thought alone, deduced the correct structure for terramycin. Nobody else could have done that at the time.
In each one of these cases, Woodward again showed how rational facts and chemical principles, combined with chemical intuition, could be used to achieve the task. In the early 1950s, Woodward, along with the British chemist Geoffrey Wilkinson, then at Harvard, postulated a novel structure for ferrocene, a compound consisting of a combination of an organic molecule with iron. This marked the beginning of the field of organometallic chemistry which grew into an industrially very significant field. Wilkinson won the Nobel Prize for this work in 1973, along with Ernst Otto Fischer. Some historians think that Woodward should have shared this prize along with Wilkinson. Remarkably, Woodward himself thought so, and voiced his thoughts in a letter sent to the Nobel Committee. Sir Geoffrey Wilkinson was an English chemist He was born 14 July 1921 in the village of Springside, near Todmorden in Yorkshire. ...
Ferrocene Fe(C5H5)2 is the prototypical metallocene, a type of organometallic chemical compound, consisting of two cyclopentadienyl rings bound on opposite sides of a central iron atom and forming an organometallic sandwich compound. ...
Organometallic chemistry is the study of chemical compounds containing bonds between carbon and a metal. ...
Ernst Otto Fischer is a German chemist. ...
Woodward won the Nobel Prize in 1965 for his synthesis of complex organic molecules. In his Nobel lecture, he described the total synthesis of the antibiotic cephalosporin, and claimed that he had pushed the synthesis schedule so that it would be completed around the time of the Nobel ceremony. The cephalosporins, are a class of β-lactam antibiotics. ...
B12 synthesis and Woodward-Hoffmann rules In the early 1960s, Woodward began work on what was the most complex natural product synthesized to date- Vitamin B12. In a remarkable collaboration with his colleague Albert Eschenmoser in Zurich, a team of almost one hundred students and postdoctoral workers worked for many years on the synthesis of this molecule. The work was finally published in 1973, and it marked a landmark in the history of organic chemistry. The synthesis included almost a hundred steps, and involved the characteristic rigorous planning and analyses that had always characterised Woodward's work. This work, more than any other, convinced organic chemists that the synthesis of any complex substance was possible, given enough time and planning. However, as of 2005, no other total synthesis of Vitamin B12 has been published. That same year, based on observations that Woodward had made during the B12 synthesis, he and Roald Hoffmann devised rules (now called the Woodward-Hoffmann rules) for elucidating the stereochemistry of the products of organic reactions. Woodward formulated his ideas (which were based on the symmetry properties of molecular orbitals) based on his experiences as a synthetic organic chemist; he asked Hoffman to perform theoretical calculations to verify these ideas, which were done using Hoffmann's Extended Hückel method. The predictions of these rules, called the "Woodward-Hoffmann rules" were verified by many experiments. Hoffmann shared the 1981 Nobel Prize for this work along with Kenichi Fukui, a Japanese chemist who had done similar work using a different approach; Woodward undoubtedly would have received a second Nobel Prize as well had he lived. Roald Hoffmann (born July 18, 1937 as Roald Safran --- Hoffmann is the surname of his stepfather) is an American theoretical chemist of Polish-Jewish origin. ...
The Woodward-Hoffmann rules devised by Robert Burns Woodward and Roald Hoffmann are a set of rules in organic chemistry predicting the stereochemistry of pericyclic reactions based on orbital symmetry. ...
The different types of isomers. ...
Organic chemistry is a specific discipline within the subject of chemistry. ...
A chemical reaction is a process that results in the interconversion of chemical substances [1]. The substance or substances initially involved in a chemical reaction are called reactants. ...
Square with symmetry group D4 Symmetry is a characteristic of geometrical shapes, equations, and other objects; we say that such an object is symmetric with respect to a given operation if this operation, when applied to the object, does not appear to change it. ...
Electron atomic and molecular orbitals In quantum chemistry (electronic structure theory), the molecular electronic states, i. ...
The extended Huckel method is a way of determining the structural geometry of an organic molecule. ...
Kenichi Fukui (ç¦äºè¬ä¸ Fukui Kenichi, October 4, 1918 â January 9, 1998) was a Japanese chemist. ...
Woodward Institute and later life While still remaining at Harvard, Woodward took on the directorship of the Woodward Research Institute, based at Basel, Switzerland in 1963. He also became a trustee of his alma mater, MIT, from 1966 to 1971 and of the Weizmann Institute of Science in Israel. Basel (British English traditionally: Basle and more recently Basel , German: Basel , French: Bâle , Italian, Spanish: Basilea and Czech: Basilej ) is Switzerlands third most populous city (166,563 inhabitants (2004); 690,000 inhabitants in the conurbation stretching across the immediate cantonal and national boundaries made Basel Switzerlands second...
The Koffler accelerator, one of the best-known buildings on campus. ...
Woodward died in Cambridge, Massachusetts from a heart attack in his sleep. At the time, he was working on the synthesis of an antibiotic, erythromycin. A student of his said about him: Cambridge City Hall Settled: 1630 â Incorporated: 1636 Zip Code(s): 02139 â Area Code(s): 617 / 857 Official website: http://www. ...
A myocardial infarction occurs when an atherosclerotic plaque slowly builds up in the inner lining of a coronary artery and then suddenly ruptures, totally occluding the artery and preventing blood flow downstream. ...
An antibiotic is a drug that kills or slows the growth of bacteria. ...
Erythromycin is a macrolide antibiotic which has an antimicrobial spectrum similar to or slightly wider than that of penicillin, and is often used for people who have an allergy to penicillins - this is not necessarily a good idea , as after all , erythromycin is itself a penicillin derivative. ...
- I owe a lot to R. B. Woodward. He showed me that one could attack difficult problems without a clear idea of their outcome, but with confidence that intelligence and effort would solve them. He showed me the beauty of modern organic chemistry, and the relevance to the field of detailed careful reasoning. He showed me that one does not need to specialize. Woodward made great contributions to the strategy of synthesis, to the deduction of difficult structures, to the invention of new chemistry, and to theoretical aspects as well. He taught his students by example the satisfaction that comes from total immersion in our science. I treasure the memory of my association with this remarkable chemist.
Many regard Woodward to be the pre-eminent organic chemist of the middle of the twentieth century.
Other notes In 1938 he married Irja Pullman, and in 1946 he married Eudoxia Muller. From the first marriage he had two daughters, and from the second one daughter and one son. During his lifetime Woodward authored or coauthored 196 publications, of which 85 are full papers, the remainder comprising preliminary communications, the text of lectures, and reviews. The pace of his scientific activity soon outstripped his capacity to publish all experimental details, and much of the work he participated was published even till a few years after his death. Woodward trained more than two hundred talented PhD. students and postdoctoral workers, many of who later went on to distinguished careers. Some of his best-known students include Yoshito Kishi (Harvard), Stuart Schreiber (Harvard), Steven A. Benner (UF), Christopher S. Foote (UCLA), Kendall Houk (UCLA), and world-renowned porphyrin chemist and former Vice Chancellor of the University of California-Davis, Prof. Kevin M. Smith. Smith was recently awarded the Robert Burns Woodward Award for Lifetime Achievement at the International Conference on Porphyrins and Pthalocyanines (ICPP- 4) held at Rome. Stuart Schreiber Stuart L. Schreiber (b. ...
K. N. Houk Kendall Newcomb Houk (b. ...
Woodward was known to be a workaholic and devoted almost all his time to chemistry. He had an encyclopaedic knowledge of chemistry, and an extraordinary memory for detail. Probably the quality that most set him apart from his peers was his remarkable ability to tie together disparate threads of knowledge from the chemical literature and bring them to bear on a chemical problem. His lectures were legendary and frequently used to last for three or four hours. In many of these, he eschewed the use of slides and used to draw beautiful structures by using coloured chalk. His famous Thursday seminars at Harvard also used to frequently last well into the night. He had a fixation with blue, and all his suits, his car, and even his parking space were coloured in blue. He detested exercise, could get along with only a few hours of sleep every night, was a heavy smoker, and enjoyed Scotch whisky and a martini or two.
Honors and awards For his work, Woodward received many awards, honors and honorary doctorates, including election to the National Academy of Sciences in 1953, and membership in academies around the world. He was also a consultant to many companies such as Polaroid, Pfizer, and Merck. Other awards include: Pfizer, Incorporated (NYSE: PFE), is the worlds largest pharmaceutical company based in New York City. ...
Merck may refer to: Merck & Co. ...
- John Scott Medal, from the Franklin Institute and City of Philadelphia, 1945
- Backeland Medal, from the North Jersey Section of the American Chemical Society, 1955
- Davy Medal, from the Royal Society in 1959
- Roger Adams Medal, from the American Chemical Society in 1961
- Pius XI Gold Medal, from the Pontifical Academy of Sciences in 1969
- National Medal of Science from the United States of America in 1964 ("For an imaginative new approach to the synthesis of complex organic molecules and, especially, for [his] brilliant syntheses of strychnine, reserphine, lysergic acid, and chlorophyll.")
- Nobel Prize in Chemistry in 1965
- Willard Gibbs Medal from the Chicago Section of the American Chemical Society in 1967
- Lavoisier Medal from the Societe Chimique de France in 1968
- The Order of the Rising Sun, Second Class from the Emperor of Japan in 1970
- Hanbury Memorial Medal from The Pharmaceutical Society of Great Britain in 1970
- Pierre Brnylants Medal from the University of Louvain in 1970
Woodward also received over twenty honorary degrees, including honorary doctorates from the following universities: John Scott (1731-1783) of Amwell, Quaker poet and friend of Samuel Johnson John Scott, American (Missouri) politician John Scott, U.S. Senator for Pennsylvania John Scott, editor of the London Magazine, killed in a duel in 1821 John Scott (1874? - September 23, 1951), Canadian newspaper editor and publisher John...
The Franklin Institute is the memorial to Benjamin Franklin, that serves to perpetuate his legacy; the museum contains many of Franklins personal effects. ...
Philadelphia is a village located in Jefferson County, New York. ...
The American Chemical Society (ACS) is a learned society (professional association) based in the United States that supports scientific inquiry in the field of chemistry. ...
Sir Humphry Davy. ...
The premises of the Royal Society in London (first four properties only). ...
Roger Adams (1889â1971) was an American organic chemist. ...
Pius XI (born Achille Ratti May 31, 1857 - Rome, February 10, 1939) was Pope from February 6, 1922 until February 10, 1939. ...
National Medal of Science The National Medal of Science, also called the Presidential Medal of Science, is an honor given by the President of the United States to individuals in science and engineering who have made important contributions to the advancement of knowledge in the fields of behavioral and social...
This is a list of Nobel Prize laureates in Chemistry from 1901 to the present day. ...
Josiah Willard Gibbs (February 11, 1839 â April 28, 1903) was an American mathematical physicist who contributed much of the theoretical foundation that led to the development of chemical thermodynamics and was one of the founders of vector analysis. ...
Nickname: The Windy City, The Second City, Chi Town Motto: Urbs In Horto (Latin: City in a Garden), I Will Location in Chicagoland and Illinois Coordinates: Country United States State Illinois Counties Cook, DuPage Incorporated March 4, 1837 Mayor Richard M. Daley (D) Area - City 606. ...
Antoine-Laurent de Lavoisier (August 26, 1743 - May 8, 1794) was a French nobleman prominent in the histories of chemistry, finance, biology, and economics. ...
Hanbury could be Hanbury, Staffordshire Hanbury, Worcestershire This article consisting of geographical locations is a disambiguation page, a list of pages that otherwise might share the same title. ...
The Catholic University of Leuven, founded in 1425, is now the names of two Belgian universities, after the original university split in 1968: the Dutch-speaking Katholieke Universiteit Leuven, Leuven, Belgium, and the French-speaking Université catholique de Louvain, Louvain-la-Neuve, Belgium This is a disambiguation page — a...
Wesleyan University founded in 1831, is a private, liberal arts university in Middletown, Connecticut. ...
Harvard redirects here. ...
The University of Cambridge (often called Cambridge University, or just Cambridge), located in Cambridge, England, is the second-oldest university in the English-speaking world. ...
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The Technion - Israel Institute of Technology (הטכניון - מכון טכנולוגי לישראל) is a university in Haifa, Israel. ...
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The University of Western Ontario (Western or UWO) is a coeducational, non-denominational, research-intensive university located in London, Ontario. ...
The Catholic University of Leuven, founded in 1425, is now the names of two Belgian universities, after the original university split in 1968: the Dutch-speaking Katholieke Universiteit Leuven, Leuven, Belgium, and the French-speaking Université catholique de Louvain, Louvain-la-Neuve, Belgium This is a disambiguation page — a...
References - "Robert Burns Woodward" by Elkan Blout in 'Biographical Memoirs'; National Academy of Sciences Press, Vol. 80, 2001.
- Robert Burns Woodward: Architect and Artist in the World of Molecules; Otto Theodor Benfey, Peter J. T. Morris, Chemical Heritage Foundation, April 2001.
- Robert Burns Woodward and the Art of Organic Synthesis: To Accompany an Exhibit by the Beckman Center for the History of Chemistry (Publication / Beckman Center for the History of Chemistry); Mary E. Bowden; Chemical Heritage Foundation, March 1992
- "Robert Burns Woodward"- Biographical Memoirs of Fellows of the Royal Society: Alexander Todd and John Cornforth (Nov. 1981)
See also - Woodward cis-hydroxylation
The Woodward cis-hydroxylation is the chemical reaction of alkenes with iodine and silver acetate in wet acetic acid to form cis-diols. ...
External links - Robert Burns Woodward
- Video podcast of Robert Burns Woodward talking about cephalosporin
| 1901: van 't Hoff 02: E.Fischer 03: Arrhenius 04: Ramsay 05: von Baeyer 06: Moissan 07: Buchner 08: Rutherford 09: Ostwald 10: Wallach 11: Curie 12: Grignard, Sabatier 13: Werner 14: Richards 15: Willstätter 18: Haber 20: Nernst 21: Soddy 22: Aston 23: Pregl 25: Zsigmondy 26: Svedberg 27: Wieland 28: Windaus 29: Harden, von Euler‑Chelpin 30: H.Fischer 31: Bosch, Bergius 32: Langmuir 34: Urey 35: F.Joliot‑Curie, I.Joliot‑Curie 36: Debye 37: Haworth, Karrer 38: Kuhn 39: Butenandt, Ružička 43: de Hevesy 44: Hahn 45: Virtanen 46: Sumner, Northrop, Stanley 47: Robinson 48: Tiselius 49: Giauque 50: Diels, Alder 51: McMillan, Seaborg 52: Martin, Synge 53: Staudinger 54: Pauling 55: du Vigneaud 56: Hinshelwood, Semyonov 57: Todd 58: Sanger 59: Heyrovský 60: Libby 61: Calvin 62: Perutz, Kendrew 63: Ziegler, Natta 64: Hodgkin 65: Woodward 66: Mulliken 67: Eigen, Norrish, Porter 68: Onsager 69: Barton, Hassel 70: Leloir 71: Herzberg 72: Anfinsen, Moore, Stein 73: E.O.Fischer, Wilkinson 74: Flory 75: Cornforth, Prelog 76: Lipscomb 77: Prigogine 78: Mitchell 79: Brown, Wittig 80: Berg, Gilbert, Sanger 81: Fukui, Hoffmann 82: Klug 83: Taube 84: Merrifield 85: Hauptman, Karle 86: Herschbach, Lee, Polanyi 87: Cram, Lehn, Pedersen 88: Deisenhofer, Huber, Michel 89: Altman, Cech 90: Corey 91: Ernst 92: Marcus 93: Mullis, Smith 94: Olah 95: Crutzen, Molina, Rowland 96: Curl, Kroto, Smalley 97: Boyer, Walker, Skou 98: Kohn, Pople 99: Zewail 2000: Heeger, MacDiarmid, Shirakawa 01: Knowles, Noyori, Sharpless 02: Fenn, Tanaka, Wüthrich 03: Agre, MacKinnon 04: Ciechanover, Hershko, Rose 05: Grubbs, Schrock, Chauvin 06: Kornberg This is a list of Nobel Prize laureates in Chemistry from 1901 to the present day. ...
Winners of the Nobel Prize are scientists, writers and peacemakers who have been awarded in their field of endeavour, and who are known collectively as either Nobel laureates or Nobel Prize winners. ...
Jacobus Henricus van t Hoff (August 30, 1852 - March 1, 1911) was a Dutch physical and organic chemist and the winner of the inaugural Nobel Prize in chemistry. ...
Hermann Emil Fischer (October 9, 1852 - July 15, 1919) was a German chemist and recipient of the Nobel Prize for Chemistry in 1902. ...
Svante August Arrhenius Svante August Arrhenius (February 19, 1859 â October 2, 1927) was a Swedish chemist and one of the founders of the science of physical chemistry. ...
William Ramsay. ...
Johann Friedrich Wilhelm Adolf von Baeyer (October 31, 1835 - August 20, 1917) was a German chemist who synthesized indigo, and was the 1905 recipient of the Nobel Prize in Chemistry. ...
The French chemist Henri Moissan (1852--1907) won the 1906 Nobel Prize in Chemistry for his work in isolating fluorine from its compounds. ...
Eduard Buchner (May 20, 1860 -- August 12, 1917) was a German chemist and zymologist, the winner of the 1907 Nobel Prize in Chemistry for his work on fermentation. ...
Ernest Rutherford Ernest Rutherford, 1st Baron Rutherford of Nelson, OM, PC, FRS (30 August 1871 â 19 October 1937), was a nuclear physicist from New Zealand. ...
Wilhelm Ostwald Friedrich Wilhelm Ostwald (commonly just Wilhelm Ostwald) (September 2, 1853 - April 4, 1932) was a German chemist. ...
Otto Wallach (March 27, 1847 at Königsberg - February 26, 1931 at Göttingen) was a German Chemist who won the Nobel Prize in 1910 for work on alicyclic compounds. ...
This article or section does not cite its references or sources. ...
François Auguste Victor Grignard (born in Cherbourg, 6 May 1871, died in Lyon, 13 December 1935) was a Nobel Prize-winning French chemist. ...
Paul Sabatier (November 5, 1854 â August 14, 1941) was a French chemist, born at Carcassonne. ...
Alfred Werner (December 12, 1866 - November 15, 1919) was a German Nobel prize-winning chemist. ...
Theodore William Richards was an American chemist. ...
Richard Willstätter Richard Martin Willstätter (August 13, 1872 â August 3, 1942) was a German chemist whose study of the structure of chlorophyll and other plant pigments won him the 1915 Nobel Prize for Chemistry. ...
Fritz Haber in 1918. ...
Walther Nernst. ...
Frederick Soddy in 1922. ...
Francis William Aston (born Birmingham, September 1, 1877; died Cambridge, November 20, 1945) was a British physicist who won the 1922 Nobel Prize in Chemistry for the invention of the mass spectrometer. ...
Fritz (Friderik) Pregl (September 3, 1869 â December 13, 1930) was an Austrian chemist of Slovenian descent. ...
Richard Zsigmondy Richard Adolf Zsigmondy (April 1, 1865 in Vienna, Austria - September 23, 1929 in Göttingen, Germany) was an Austrian-German chemist (his family was originally from Hungary) who studied colloids. ...
Theodor (The) Svedberg (August 30, 1884 – February 25, 1971) was a Swedish chemist and Nobel laureate. ...
Heinrich Otto Wieland (June 4, 1877 â August 5, 1957) was a German chemist. ...
Adolf Otto Reinhold Windaus (December 25, 1876 – June 9, 1959) was a significant German chemist. ...
Arthur Harden (October 12, 1865 – June 17, 1940) was an English biochemist. ...
Hans Karl August Simon von Euler-Chelpin (February 15, 1873 – November 6, 1964) was a Swedish (German-born) biochemist. ...
Hans Fischer was a German organic chemist. ...
Carl Bosch (August 27, 1874 - April 26, 1940) was a German chemist and engineer. ...
Friedrich Bergius (October 11, 1884 - March 30, 1949) was born near Breslau, Germany (now Wroclaw in Poland). ...
Irving Langmuir -- chemist and physicist Irving Langmuir (January 31, 1881 in Brooklyn, New York - August 16, 1957 in Woods Hole, Massachusetts) was an American chemist and physicist. ...
Harold Urey, circa 1963. ...
Frédéric Joliot-Curie Jean Frédéric Joliot-Curie né Joliot (March 19, 1900 â August 14, 1958) was a French physicist and Nobel laureate. ...
Irène Joliot-Curie Irène Joliot-Curie née Curie (September 12, 1897 â March 17, 1956) was a French scientist, the daughter of Marie and Pierre Curie and the wife of Frédéric Joliot-Curie. ...
Petrus Josephus Wilhelmus Debije (March 24, 1884 â November 2, 1966) was a Dutch physical chemist. ...
Sir Walter Norman Haworth (born Chorley, Lancashire March 19, 1883 â March 19, 1950) was a British chemist who is best known for his groundbreaking work on ascorbic acid (vitamin C) whilst working at Birmingham University. ...
Paul Karrer (April 21, 1889 â June 18, 1971) was a Swiss organic chemist best known for his work on vitamins. ...
Richard Kuhn (December 3, 1900 – August 1, 1967) was a German biochemist, born in Vienna, Austria. ...
Adolf Friedrich Johann Butenandt (March 24, 1903 - January 18, 1995) was a German biochemist. ...
Lavoslav (Leopold) RužiÄka (September 13, 1887 â September 26, 1976) was a winner of Nobel Prize in Chemistry, the first one from Croatia. ...
George Charles de Hevesy (born as Hevesy György, also known as Georg Karl von Hevesy) (August 1, 1885 in Budapest â July 5, 1966) was a Hungarian chemist who was important in the development of the tracer method where radioactive tracers are used to study chemical processes, e. ...
Otto Hahn (March 8, 1879 â July 28, 1968) was a German chemist. ...
Artturi Ilmari Virtanen (IPA: ) (January 15, 1895 â November 11, 1973) was a Finnish chemist and recipient of the Nobel Prize in Chemistry. ...
James Batcheller Sumner (November 19, 1887 - August 12, 1955) was an American chemist. ...
John Howard Northrop (July 5, 1891 â May 27, 1987) was an American biochemist who won the Nobel Prize in Chemistry in 1946 (with James Batcheller Sumner and Wendell Meredith Stanley) for purifying and crystallizing certain enzymes. ...
Wendell Meredith Stanley (August 16, 1904 â June 15, 1971) was an American biochemist, virologist and Nobel prize laureate. ...
Sir Robert Robinson (1886 - 1975). ...
Arne Wilhelm Kaurin Tiselius (Stockholm 10 August 1902 – Uppsala 29 October 1971), Swedish biochemist. ...
William Giauque (May 12, 1895 – March 28, 1982) won the Nobel Prize in Chemistry in 1949 for his studies in the properties of matter at temperatures close to absolute zero. ...
Otto Paul Hermann Diels (January 23, 1876 - March 7, 1954), a German chemist. ...
Kurt Alder (10 July 1902 - 20 June 1958) was a German chemist who won the Nobel Prize in Chemistry jointly with Otto Paul Hermann Diels in 1950. ...
Edwin Mattison McMillan (September 18, 1907-September 7, 1991) was the first scientist to produce a transuranium element. ...
Glenn T. Seaborg Glenn Theodore Seaborg (April 19, 1912 â February 25, 1999) was an American chemist prominent in the discovery and isolation of ten transuranic elements including plutonium, americium, curium, berkelium, californium, einsteinium, fermium, mendelevium, nobelium and seaborgium, which was named in his honor. ...
Archer John Porter Martin was a British chemist and Nobel Prize winner. ...
Richard Laurence Millington Synge (born Liverpool, October 28, 1914, died Norwich, August 18, 1994) was a British biochemist, and winner of the 1952 Nobel Prize in Chemistry for the invention of partition chromatography. ...
Hermann Staudinger (March 23, 1881 in Worms- Sept. ...
Linus Carl Pauling (February 28, 1901 â August 19, 1994) was an American quantum chemist and biochemist, widely regarded as the premier chemist of the twentieth century. ...
Vincent du Vigneaud (May 18, 1901 - December 11, 1978) was a U.S. biochemist. ...
Sir Cyril Norman Hinshelwood was an English physical chemist. ...
Nikolay Nikolayevich Semyonov (Никола́й Никола́евич Семёнов) (April 15 (April 3, Old Style), 1896 – September 25, 1986) was a Russian/Soviet physicist and chemist. ...
The Right Honourable Alexander Robert Todd, Baron Todd, OM, FRS (2 October 1907â10 January 1997) was a British biochemist whose research on the structure and synthesis of nucleotides, nucleosides, and nucleotide coenzymes gained him the 1957 Nobel Prize for Chemistry. ...
Frederick Sanger, OM, CH, CBE, FRS (born 13 August 1918) is an English biochemist and a two times Nobel laureate in Chemistry. ...
Jaroslav Heyrovský listen â¶(?) (December 20, 1890 â March 27, 1967) was a Czech chemist who was awarded the Nobel Prize in chemistry in 1959. ...
Willard Frank Libby (December 17, 1908 â September 8, 1980) was an American chemist, famous for his role in the development of radiocarbon dating, a process which revolutionized archaeology. ...
Melvin Calvin Melvin Calvin (April 8, 1911 â January 8, 1997) was a chemist most famed for discovering the Calvin cycle (along with Andrew Benson), for which he was awarded the 1961 Nobel Prize in Chemistry. ...
Max Ferdinand Perutz (May 19, 1914 - February 6, 2002) was an Austrian-British molecular biologist. ...
This article or section does not cite its references or sources. ...
Karl Waldemar Ziegler (November 26, 1898 â August 11, 1973) was a German chemist who won the Nobel Prize in Chemistry in 1963, with Giulio Natta, for work on high polymers. ...
Giulio Natta (February 26, 1903 â May 2, 1979) was an Italian chemist. ...
Dorothy Mary Crowfoot Hodgkin, OM , FRS (May 12, 1910 â July 29, 1994) was a British scientist, born Dorothy Mary Crowfoot in Cairo. ...
Robert Sanderson Mulliken (June 7, 1896 â October 31, 1986) was an American physicist and chemist, primarily responsible for the elaboration of the molecular orbital method of computing the structure of molecules. ...
Manfred Eigen (born May 9, 1927, Bochum) is a German biophysicist and a former director of the Max Planck Institute for Biophysical Chemistry in Göttingen. ...
Ronald George Wreyford Norrish (November 9, 1897 â June 7, 1978) was a British chemist. ...
The Right Honourable George Porter, Baron Porter of Luddenham, OM, FRS (6 December 1920â31 August 2002) was an English chemist. ...
Lars Onsager (November 27, 1903 â October 5, 1976) was a Norwegian physical chemist, winner of the 1968 Nobel Prize in Chemistry. ...
Sir Derek Harold Richard Barton was a British physical chemist and Nobel Prize Laureate. ...
Odd Hassel was a Norwegian physical chemist and Nobel Laureate. ...
Luis Federico Leloir, born September 6, 1906 – died December 2, 1987, was a biochemist born in Paris but who lived all his life in Argentina. ...
Gerhard Herzberg (December 25, 1904 â March 3, 1999) was a pioneering theoretical chemist. ...
Christian Boehmer Anfinsen, Jr. ...
Stanford Moore (September 4, 1913 â August 23, 1982) was a U.S. biochemist. ...
William Howard Stein (1911 - 1980) was a U.S. biochemist. ...
Ernst Otto Fischer is a German chemist. ...
Sir Geoffrey Wilkinson was an English chemist He was born 14 July 1921 in the village of Springside, near Todmorden in Yorkshire. ...
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Sir John Kappa Cornforth was born in Australia, and has been profoundly deaf since his teens. ...
Vladimir Prelog (July 23, 1906 â January 7, 1998) was a renowned Bosnian - Croatian chemist who worked in Prague, Zagreb and Zurich and who won the Nobel Prize in chemistry in 1975. ...
William Nunn Lipscomb, Jr. ...
Ilya Prigogine (January 25, 1917 â May 28, 2003) was a Belgian physicist and chemist noted for his work on dissipative structures, complex systems, and irreversibility. ...
Peter D. Mitchell (September 29, 1920- April 10, 1992) was a British biochemist who was awarded the 1978 Nobel Prize for Chemistry for formulation of the chemiosmotic theory of mitochondrial function. ...
Herbert Charles Brown (May 22, 1912 â December 19, 2004) was a chemist who won the Nobel Prize in Chemistry in 1979 (along with Georg Wittig) for his work with organoboranes. ...
Georg Wittig (June 16, 1897 in Berlin (Germany) - August 26, 1987) was a german chemist who reported a method for synthesis of alkenes from aldehydes and ketones using compounds called phosphonium ylides. ...
Paul Berg, born June 30, 1926 in Brooklyn, New York, USA, is an American biochemist and professor emeritus at Stanford University. ...
Walter Gilbert Walter Gilbert (born March 21, 1932) is an American physicist, biochemist, entrepreneur, and molecular biology pioneer. ...
Frederick Sanger, OM, CH, CBE, FRS (born 13 August 1918) is an English biochemist and a two times Nobel laureate in Chemistry. ...
Kenichi Fukui (ç¦äºè¬ä¸ Fukui Kenichi, October 4, 1918 â January 9, 1998) was a Japanese chemist. ...
Roald Hoffmann (born July 18, 1937 as Roald Safran --- Hoffmann is the surname of his stepfather) is an American theoretical chemist of Polish-Jewish origin. ...
Sir Aaron Klug, OM, FRS (born 11 August 1926 in Zelvas, Lithuania ) is a Lithuanian-born British physicist and chemist, and winner of the 1982 Nobel Prize in Chemistry for his development of crystallographic electron microscopy. ...
Professor Henry Taube, Ph. ...
Robert Bruce Merrifield (July 15, 1921 â May 14, 2006) was an American biochemist who won the Nobel Prize in Chemistry in 1984. ...
Dr. Herbert A. Hauptman (born February 14, 1917) is a world renowned American mathematician and Nobel laureate. ...
Jerome Karle is an American physical chemist. ...
Dudley Robert Herschbach (born June 18, 1932), a chemist and Frank B. Baird Jr. ...
Yuan Tseh Lee (Chinese: æé å² Pinyin: LÇ YuÇnzhé, Wade-Giles: Li³ Yüan³-che²) (born November 19, 1936) is a famous chemist. ...
John Charles Polanyi (born January 23, 1929) is a Canadian chemist. ...
Donald James Cram (April 22, 1919 â June 17, 2001) was an American chemist who shared the 1987 Nobel Prize in Chemistry for âsynthesizing three-dimensional molecules that could mimic the functioning of natural molecules. ...
Jean-Marie Lehn (born September 30, 1939) is a French chemist. ...
Charles J. Pedersen (October 3, 1904âOctober 26, 1989) was an American organic chemist best known for describing methods of synthesizing crown ethers. ...
Johann Deisenhofer (born September 30, 1943) is a German biochemist who, along with Hartmut Michel and Robert Huber, received the Nobel Prize for Chemistry in 1988 for their determination of the structure of a membrane-bound complex of proteins and co-factors that is essential to photosynthesis. ...
Robert Huber is a German biochemist and Nobel laureate. ...
Hartmut Michel is a German biochemist and Nobel Laureate. ...
Sidney Altman (born May 7, 1939) is a Canadian-born molecular biologist, who is currently the Sterling Professor of Molecular, Cellular, and Developmental Biology and Chemistry at Yale University. ...
Thomas R. Cech was born on December 8, 1947 in Chicago. ...
Elias James Corey (born July 12, 1928) is an American organic chemist. ...
Richard Robert Ernst (born August 14, 1933) is a Swiss chemist and Nobel Laureate. ...
Rudolph Rudy Arthur Marcus (born July 21, 1923) received the 1992 Nobel Prize in Chemistry for his theory of Electron transfer. ...
Kary Banks Mullis (b. ...
Michael Smith, C.C., O.B.C., Ph. ...
George Andrew Olah (born May 22, 1927 as György Oláh) is a Hungarian-born American chemist. ...
Paul J. Crutzen (December 3rd, 1933 - ) is a Dutch nobel prize winning atmospheric chemist. ...
Mario Molina (left) with Luis E. Miramontes Mario J. Molina (born March 19, 1943) was awarded the 1995 Nobel Prize in Chemistry for his role in elucidating the threat to the Earths ozone layer of chlorofluorocarbon gases (or CFCs). ...
Frank Sherwood Rowland (born June 28, 1927) is a Nobel laureate and a professor of chemistry at the University of California, Irvine. ...
Robert Floyd Curl, Jr. ...
Sir Harold Walter Kroto KBE , FRS , Ph. ...
Richard Errett Smalley Richard Errett Smalley (June 6, 1943 â October 28, 2005) was the Gene and Norman Hackerman Professor of Chemistry and a Professor of Physics and Astronomy at Rice University, in Houston, Texas. ...
Paul Delos Boyer (born July 31, 1918) is an American biochemist. ...
John Ernest Walker (born January 7, 1941) is an English chemist who won the Nobel Prize in Chemistry in 1997. ...
Jens Christian Skou (born October 8, 1918) is a Danish chemist and Nobel laureate. ...
Walter Kohn (born March 9, 1923 in Vienna, Austria) is an Austrian-born American physicist who was awarded, with John A. Pople, the Nobel Prize in chemistry in 1998. ...
Sir John Anthony Pople (October 31, 1925 â March 15, 2004) was a theoretical chemist. ...
Ahmed Zewail Ahmed Hassan Zewail (Arabic: Ø£ØÙ
د زÙÙÙ) (born February 26, 1946) is an Egyptian American chemist, and the winner of the 1999 Nobel Prize in Chemistry for his work on femtochemistry. ...
Alan J. Heeger (born 22 January 1936 in Sioux City, Iowa) is a United States chemistry and physics academic and nobel prize winner. ...
Alan Graham MacDiarmid ONZ, (born April 24, 1927) is a chemist. ...
Professor Hideki Shirakawa ç½å· è±æ¨¹ Shirakawa Hideki, born in Tokyo on August 20, 1936) is a Japanese chemist and winner of the 2000 Nobel Prize in Chemistry for his discovery of conductive polymers together with Alan J. Heeger and Alan G MacDiarmid. ...
William S. Knowles (born June 1, 1917) is a American chemist. ...
Ryoji Noyori (éä¾è¯æ²») (born September 3, 1938) won the Nobel Prize in Chemistry in 2001. ...
Karl Barry Sharpless (born April 28, 1941) is an American chemist renowned for his work on organometallic chemistry. ...
Dr. John B. Fenn Dr. John Bennett Fenn (born June 15, 1917 in New York City) is a research professor of analytical chemistry who was awarded the Nobel Prize in Chemistry in 2002. ...
Koichi Tanaka (ç°ä¸ èä¸, born August 3, 1959) is a Japanese scientist who won the Nobel Prize in Chemistry in 2002 for developing a novel method for mass spectrometric analyses of biological macromolecules. ...
Kurt Wüthrich (born October 4, 1938) is a Swiss chemist and Nobel laureate. ...
Peter Agre (born January 30, 1949) is an American biologist who was awarded the 2003 Nobel Prize in Chemistry (which he shared with Roderick MacKinnon) for his discovery of aquaporins. ...
Roderick MacKinnon (born 19 February 1956 in Burlington, Massachusetts) is a professor of Molecular Neurobiology and Biophysics at Rockefeller University who in 2003 was awarded the Nobel Prize in Chemistry for his work on the structure and operation of ion channels. ...
Aaron Ciechanover (אהרון צחנובר) (born October 1, 1947) is an Israeli biologist. ...
Avram Hershko (born December 31, 1937) is an Israeli biologist. ...
Irwin A. Rose (born 16 July 1926 in NY) is an American biologist. ...
Robert H. Grubbs (b. ...
Richard Royce Schrock (born January 4, 1945) was one of the recipients of the 2005 Nobel Prize in Chemistry for his contribution to the metathesis method in organic chemistry. ...
Yves Chauvin (born October 10, 1930) is a French chemist and Nobel Prize winner. ...
Roger D. Kornberg Roger David Kornberg (born April 24, 1947) is an American scientist and professor of structural biology at Stanford University School of Medicine. ...
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