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benzo.org.uk : SSRIs, Drug Withdrawal & Abuse: Problem or Treatment? CH Ashton & AH Young, 1999 (6334 words) |
 | Advantages of SSRIs include: greater tolerability and safety and a wider range of clinical applications, one of which is a potential use in the treatment of drug abuse and some eating disorders (see also: Chapter 4). |
 | A second factor proposed to account for SSRI withdrawal effects is a decline in serotonergic transmission, although there is no direct evidence for this and the mechanisms for producing particular withdrawal symptoms are obscure. |
 | SSRIs, including zimelidine, citalopram, viqualine and fluoxetine have been shown in controlled studies to decrease alcohol consumption in non-depressed alcoholics and heavy or problem drinkers. |
| Medinfo: SSRIs (586 words) |
 | SSRIs, Selective Serotonin Re-uptake Inhibitors, are a widely used group of antidepressants, which includes such drugs as fluoxetine (Prozac) and paroxetine (Seroxat). |
 | SSRIs are mostly used for treatment of depression, but individual members of the group have other, specialised uses eg anxiety, panic disorder, obsessive compulsive disorder, eating disorders, and social phobia. |
 | SSRIs only work after they have built up in your system, and thus need to be taken regularly, and will start to have their effects after two weeks or more. |