Sidney Altman

Sidney Altman (born May 7, 1939) is a Canadian-born molecular biologist, who is currently the Sterling Professor of Molecular, Cellular, and Developmental Biology and Chemistry at Yale University. In 1989 he shared the Nobel Prize in Chemistry with Thomas R. Cech for their work on the catalytic properties of RNA. Image File history File linksMetadata Size of this preview: 450 × 599 pixelsFull resolution (1554 × 2070 pixel, file size: 2. ... Image File history File linksMetadata Size of this preview: 450 × 599 pixelsFull resolution (1554 × 2070 pixel, file size: 2. ... May 7 is the 127th day of the year in the Gregorian calendar (128th in leap years). ... 1939 (MCMXXXIX) was a common year starting on Sunday (link will display full year calendar). ... Molecular biology is the study of biology at a molecular level. ... A Sterling Professorship is the highest academic rank at Yale University, awarded to a tenured faculty member considered one of the best in his field. ... “Yale” redirects here. ... This is a list of Nobel Prize laureates in Chemistry from 1901 to 2006. ... Thomas R. Cech received Nobel Prize in 1989 because he discovered the catalytic properties of RNA with Sidney Altman. ... This article or section does not adequately cite its references or sources. ...

Education

He was born in Montreal, Quebec. He received his bachelor's degree in physics from MIT in 1960, spent 18 months as a graduate student in physics at Columbia University, and then earned a Ph.D. in biophysics from the University of Colorado in 1967. This article needs cleanup. ... A bachelors degree (Artium Baccalaureus, A.B. or B.A.) is usually an undergraduate academic degree awarded for a course or major that generally lasts for three, four, or in some cases and countries, five or six years. ... The Massachusetts Institute of Technology (MIT) is a private, coeducational research university located in Cambridge, Massachusetts. ... 1960 (MCMLX) was a leap year starting on Friday (the link is to a full 1960 calendar). ... Physics (Greek: (phúsis), nature and (phusiké), knowledge of nature) is the science concerned with the fundamental laws of the universe. ... Columbia University is a private research university in the United States. ... Doctor of Philosophy, abbreviated Ph. ... Biophysics (also biological physics) is an interdisciplinary science that applies the theories and methods of physics, to questions of biology. ... The University of Colorado at Boulder (CU-Boulder, UCB officially[2]; Colorado, CU colloquially) is the flagship university of the University of Colorado system. ... 1967 (MCMLXVII) was a common year starting on Sunday of the Gregorian calendar (the link is to a full 1967 calendar). ...

Nobel prize work

Sidney Altman received his work for discovering the catalytic properties of the ribozyme RNase P. RNase P is a ribonucleoprotein particle consisting of both a structural RNA molecule as well as one (in prokaryotes) or more (in eukaryotes) proteins. Originally, it was believed that in the bacterial RN ase P complex the protein subunit was responsible for the catalytic activity of the complex, which is involved in the maturation of pre-RNAs. During experiments in which the complex was reconstituted in test tubes, Sidney Altman and his group discovered that the RNA molecule alone was sufficient for the observed catalytic activity, meaning that the RNA itself had catalytic properties, which was the discovery that earned him the Nobel prize. Although the RNase P complex also exists in eukaryotic organisms, his later work revealed that in those organisms, the protein subunits of the complex are essential to the catalytic activity, in contrast to the bacterial RNase P. // A ribozyme (from ribonucleic acid enzyme, also called RNA enzyme or catalytic RNA) is an RNA molecule that catalyzes a chemical reaction. ... Crystal structure of RNase P with substrate tRNA (green), PDB 2A64 RNase P is a type of ribonuclease and is currently under heavy research. ... Ribonucleoprotein(RNP) is a compound that combined ribonucleic acid (RNA) and protein together. ... Prokaryotes are unicellular (in rare cases, multicellular) organisms without a nucleus. ... Kingdoms Eukaryotes are organisms with complex cells, in which the genetic material is organized into membrane-bound nuclei. ... A representation of the 3D structure of myoglobin, showing coloured alpha helices. ... Maturation is the increase in the state of maturity. ... This article or section does not adequately cite its references or sources. ...