Southern Arizona is a region of the United States. It is the southernmost portion of the 48th state, Arizona. Southern Arizona's boundaries are not well defined, but certainly include all of present-day Cochise County, Pima County, and Santa Cruz County. State nickname: The Grand Canyon State, The Copper State Other U.S. States Capital Phoenix Largest city Phoenix Governor Janet Napolitano (D) Official languages English Only State Area 295,254 km² (6th)  - Land 294,312 km²  - Water 942 km² (0. ... Cochise County is located in the southeastern corner of the state of Arizona. ... Pima County is located in the south central part of the U.S. state of Arizona. ... Santa Cruz County is located in the south of the U.S. state of Arizona. ...

The principal cities of the area include Tucson, Sierra Vista, Oro Valley, Nogales, Marana, and Douglas. There are no other cities in the area with more than 10,000 persons. A large Native American reservation, the Tohono O'odham nation, lies in the western desert portions of the area. Tucson (pronounced ) is a city and the county seat of Pima County, Arizona. ... Sierra Vista is a city located in Cochise County, Arizona. ... The town of Oro Valley, AZ as seen from the Oro Valley Public Library. ... Nogales, Santa Cruz Co. ... Marana is a town located in Pima County, Arizona. ... Douglas is a city located in Cochise County, Arizona. ... Native Americans (also Indians, Aboriginal Peoples, American Indians, First Nations, Alaskan Natives, Amerindians, or Indigenous Peoples of America) are the indigenous inhabitants of The Americas prior to the European colonization, and their modern descendants. ... Traditional basketmaking, 1916 The Tohono Oodham are a Native American tribe formerly known as the Papago who reside primarily in the Sonoran Desert. ...