Stanley Prusiner

Born	May 28, 1942 Des Moines, Iowa, United States
Residence	San Francisco, United States
Nationality	American
Field	Neurology, infectious disease
Institution	University of California, San Francisco
Alma mater	University of Pennsylvania
Known for	Prions Transmissible spongiform encephalopathy Creutzfeldt-Jakob disease
Notable prizes	Nobel Prize in Physiology or Medicine (1997) Potamkin Prize (1991) Lasker Award (1994)

Stanley Ben Prusiner (born May 28, 1942^[1]) is an American neurologist and biochemist. Currently the director of the Institute for Neurodegenerative Diseases at University of California, San Francisco (UCSF), Prusiner discovered prions, a class of infectious self-reproducing pathogens solely composed of protein. For his prion research he received the Albert Lasker Award for Basic Medical Research in 1994 and the Nobel Prize in Physiology or Medicine in 1997. Before you can upload images you will need to register an account Only use this if you hold the copyright on the image. ... May 28 is the 148th day of the year in the Gregorian calendar (149th in leap years). ... Year 1942 (MCMXLII) was a common year starting on Thursday (the link is to a full 1942 calendar). ... Nickname: Hartford of the West, City of Skywalks, Raccoon City, DSM Location in the State of Iowa, USA Coordinates: Country United States State Iowa County Polk County Incorporated September 22, 1851 Government  - Mayor Frank Cownie Area  - City  77. ... This page is a candidate for speedy deletion. ... Neurology is a branch of medicine dealing with disorders of the nervous system. ... This false-colored electron micrograph shows a malaria sporozoite migrating through the midgut epithelia. ... UCSF in 1908, with the streetcar that used to run on Parnassus Avenue The University of California, San Francisco (UCSF) is one of the worlds leading centers of health sciences research, patient care, and education. ... This article is about the private Ivy League university in Philadelphia. ... A prion (IPA: .[1][2] ) — short for proteinaceous infectious particle that lacks nucleic acid (by analogy to virion) — is a type of infectious agent made only of protein. ... Transmissible spongiform encephalopathies (TSEs, also known as prion diseases) are a group of progressive conditions that affect the brain and nervous system of humans and animals and are transmitted by prions. ... Creutzfeldt-Jakob disease (CJD) is a very rare and incurable degenerative neurological disorder (brain disease) that is ultimately fatal. ... Image File history File links Nobel. ... List of Nobel Prize laureates in Physiology or Medicine from 1901 to the present day. ... The Potamkin Prize was established in 1988 and is sponsored by the American Academy of Neurology. ... The Albert Lasker Medical Research Awards have been awarded annually since 1946 to living persons who have made major contributions to medical science. ... May 28 is the 148th day of the year in the Gregorian calendar (149th in leap years). ... Year 1942 (MCMXLII) was a common year starting on Thursday (the link is to a full 1942 calendar). ... Neurology is a branch of medicine dealing with disorders of the nervous system. ... Biochemistry is the study of the chemical processes and transformations in living organisms. ... UCSF in 1908, with the streetcar that used to run on Parnassus Avenue The University of California, San Francisco (UCSF) is one of the worlds leading centers of health sciences research, patient care, and education. ... A prion (IPA: .[1][2] ) — short for proteinaceous infectious particle that lacks nucleic acid (by analogy to virion) — is a type of infectious agent made only of protein. ... An infection is the detrimental colonization of a host organism by a foreign species. ... Biological reproduction is the biological process by which new individual organisms are produced. ... A pathogen or infectious agent is a biological agent that causes disease or illness to its host. ... A representation of the 3D structure of myoglobin, showing coloured alpha helices. ... The Albert Lasker Award for Basic Medical Research is awarded by the Lasker Foundation for the understanding, diagnosis, prevention, treatment, and cure of disease. ... List of Nobel Prize laureates in Physiology or Medicine from 1901 to the present day. ...

Prusiner was born in Des Moines, Iowa and spent his childhood in Des Moines and Cincinnati, Ohio, where he attended Walnut Hills High School. Prusiner received a Bachelor of Science degree in chemistry from the University of Pennsylvania and later received his M.D. from the University of Pennsylvania School of Medicine.^[1] Prusiner then completed an internship in medicine at the University of California, San Francisco. Later Prusiner moved to the National Institutes of Health, where he studied glutaminases in E. coli in the laboratory of Earl Stadtman. After three years at NIH, Prusiner returned to UCSF to complete a residency in neurology. Upon completion of the residency in 1974, Prusiner joined the faculty of the UCSF neurology department. Since that time, Prusiner has held various faculty and visiting faculty positions at both UCSF and UC Berkeley. Nickname: Hartford of the West, City of Skywalks, Raccoon City, DSM Location in the State of Iowa, USA Coordinates: Country United States State Iowa County Polk County Incorporated September 22, 1851 Government  - Mayor Frank Cownie Area  - City  77. ... Nickname: The Queen City Location in Hamilton County, Ohio, USA Coordinates: Country United States State Ohio County Hamilton Founded 1788 Incorporated 1802 (village) - 1819 (city) Government type Strong mayor  - Mayor Mark L. Mallory (D) Area    - City  79. ... Walnut Hills High School is a public college-preparatory classical high school in Cincinnati, Ohio, United States. ... A Bachelor of Science (B.S., B.Sc. ... A degree is any of a wide range of status levels conferred by institutions of higher education, such as universities, normally as the result of successfully completing a program of study. ... This article or section includes a list of works cited or a list of external links, but its sources remain unclear because it lacks in-text citations. ... This article is about the private Ivy League university in Philadelphia. ... Doctor of Medicine (M.D. or MD, from the Latin Medicinae Doctor meaning teacher of medicine,) is an academic degree for medical doctors. ... The University of Pennsylvanias School of Medicine, presently located in the University City section of Philadelphia, Pennsylvania, was the countrys first school of medicine, founded at the College of Philadelphia, as the University was then called. ... For information about a medical intern, see the article on Medical residency. ... The National Institutes of Health (NIH) is the primary agency of the United States government responsible for medical research. ... E. coli redirects here. ... Residency is a stage of postgraduate medical training in North America and leads to eligibility for board certification in a primary care or referral specialty. ... Neurology is a branch of medicine dealing with disorders of the nervous system. ... Sather tower (the Campanile) looking out over the San Francisco Bay and Mount Tamalpais. ...

Prusiner won the Nobel Prize in Physiology or Medicine in 1997 for his work proposing an explanation for the cause of bovine spongiform encephalopathy ("mad cow disease") and its human equivalent, Creutzfeldt-Jakob disease.^[1] In this work, he coined the term prion, which comes from "proteinaceous infectious particle that lacks nucleic acid" to refer to a previously undescribed form of infection due to protein misfolding.^[2] Classic image of cattle with BSE. Frantic digging going nowhere. ... Creutzfeldt-Jakob disease (CJD) is a very rare and incurable degenerative neurological disorder (brain disease) that is ultimately fatal. ... A nucleic acid is a complex, high-molecular-weight biochemical macromolecule composed of nucleotide chains that convey genetic information. ...

Prusiner was elected to the National Academy of Science in 1992 and to its governing council in 2007. He is also an elected member of the American Academy of Arts and Sciences (1993), the Royal Society (1996), the American Philosophical Society (1998), the Serbian Academy of Sciences and Arts (2003), and the Institute of Medicine. President Harding and the National Academy of Sciences at the White House, Washington, DC, April 1921 The National Academy of Sciences (NAS) is a corporation in the United States whose members serve pro bono as advisers to the nation on science, engineering, and medicine. ... The House of the Academy, Cambridge, Massachusetts. ... The premises of The Royal Society in London (first four properties only). ... The American Philosophical Society is a discussion group founded as the Junto in 1743 by Benjamin Franklin. ... The Serbian Academy of Sciences and Arts (Serbian: Српска академија наука и уметности) was founded in 1886 as the Serbian Royal Academy of Sciences and Arts. ...

Awards

• Potamkin Prize for Alzheimer’s Disease Research from the American Academy of Neurology (1991)
• The Richard Lounsberry Award for Extraordinary Scientific Research in Biology and Medicine from the National Academy of Sciences (1993)
• The Gairdner Foundation International Award (1993)
• The Albert Lasker Award for Basic Medical Research (1994)
• The Paul Ehrlich Prize from the Federal Republic of Germany (1995)
• The Wolf Prize in Medicine from the Wolf Foundation/State of Israel (1996)
• The Keio International Award for Medical Science (1996)
• The Louisa Gross Horwitz Prize from Columbia University (1997)
• The Nobel Prize in Physiology or Medicine (1997)

The Potamkin Prize was established in 1988 and is sponsored by the American Academy of Neurology. ... The Gairdner Foundation International Award is given annually at a special dinner to three to six people for outstanding discoveries or contributions to medical science. ... The Albert Lasker Award for Basic Medical Research is awarded by the Lasker Foundation for the understanding, diagnosis, prevention, treatment, and cure of disease. ... Past winners of the Wolf Prize in Medicine: 1978 George D. Snell, Jean Dausset, Jon J. van Rood 1979 Roger W. Sperry, Arvid Carlsson, Oleh Hornykiewicz 1980 Cesar Milstein, Leo Sachs, Sir James L. Gowans 1981 Barbara McClintock, Stanley N. Cohen 1982 Jean-Pierre Changeux, Solomon H. Snyder, Sir James... List of Nobel Prize laureates in Physiology or Medicine from 1901 to the present day. ...

References

1. ^ ^{a b c} Stanley B. Prusiner - Autobiography. NobelPrize.org. Retrieved on 2007 January 2.
2. ^ "What really causes mad cow disease?", Wired, January 31, 2007. Retrieved on 2007 January 2.

• Prusiner S. B. (1982). "Novel proteinaceous infectious particles cause scrapie". Science 216: 136 - 144. DOI:10.1126/science.6801762. 
• Prusiner S. B. (1991). "Molecular biology of prion diseases". Science 252: 515 - 1522. DOI:10.1126/science.1675487. 

2007 (MMVII) is the current year, a common year starting on Monday of the Gregorian calendar and the Anno Domini (common) era. ... January 2 is the second day of the year in the Gregorian calendar. ... January 31 is the 31st day of the year in the Gregorian calendar. ... 2007 (MMVII) is the current year, a common year starting on Monday of the Gregorian calendar and the Anno Domini (common) era. ... 2007 (MMVII) is the current year, a common year starting on Monday of the Gregorian calendar and the Anno Domini (common) era. ... January 2 is the second day of the year in the Gregorian calendar. ... A digital object identifier (or DOI) is a standard for persistently identifying a piece of intellectual property on a digital network and associating it with related data, the metadata, in a structured extensible way. ... A digital object identifier (or DOI) is a standard for persistently identifying a piece of intellectual property on a digital network and associating it with related data, the metadata, in a structured extensible way. ...

External links

• Prusiner's Nobel Prize page
• UCSF page