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Encyclopedia > Water intoxication

Water intoxication (also known as hyperhydration or water poisoning) is a potentially fatal disturbance in brain function that results when the normal balance of electrolytes in the body is pushed outside of safe limits, ironically by that which makes up the majority of it - common water.[1] Normal, healthy (both physically and nutritionally) individuals have little to worry about accidentally overconsuming water. Nearly all deaths related to water intoxication in normal individuals have resulted either from water drinking contests, in which individuals attempt to consume several gallons over the course of just a few minutes, or long bouts of intensive exercise during which time electrolytes are not properly replenished, yet massive amounts of fluid are still consumed. An electrolyte is a substance containing free ions that behaves as an electrically conductive medium. ... Impact from a water drop causes an upward rebound jet surrounded by circular capillary waves. ...

Contents

Physiology

Blood contains electrolytes (particularly sodium compounds, such as sodium chloride) in concentrations that must be held within very narrow limits. Water enters the body orally or intravenously and leaves the body primarily in urine, sweat, and water vapor. If water enters the body more quickly than it can be removed, body fluids are diluted and a potentially dangerous shift in electrolyte balance occurs. In other words, the body has too much water and not enough electrolytes. Human blood smear: a - erythrocytes; b - neutrophil; c - eosinophil; d - lymphocyte. ... An electrolyte is a substance containing free ions that behaves as an electrically conductive medium. ... For sodium in the diet, see Edible salt. ... R-phrases 36 S-phrases none Flash point Non-flammable Related Compounds Other anions NaF, NaBr, NaI Other cations LiCl, KCl, RbCl, CsCl, MgCl2, CaCl2 Related salts Sodium acetate Supplementary data page Structure and properties n, εr, etc. ... Oral (Russian: Уральск, Uralsk , also spelled Uralsk) is a city in western Kazakhstan, along the Ural (Zhayyq) River. ... An intravenous drip in a hospital Intravenous therapy or IV therapy is the administration of liquid substances directly into a vein. ... This article or section is in need of attention from an expert on the subject. ... SWEAT is an OLN/TSN show hosted by Julie Zwillich that aired in 2003-2004. ... Water vapor or water vapour (see spelling differences), also aqueous vapor, is the gas phase of water. ...


Most water intoxication is caused by hyponatremia, an overdilution of sodium in the blood plasma, which in turn causes an osmotic shift of water from extracellular fluid (outside of cells) to intracellular fluid (within cells). The cells swell as a result of changes in osmotic pressure and may cease to function. When this occurs in the cells of the central nervous system and brain, water intoxication is the result. Additionally, many other cells in the body may undergo cytolysis, wherein cell membranes that are unable to stand abnormal osmotic pressures rupture, killing the cells. Initial symptoms typically include light-headedness, sometimes accompanied by nausea, vomiting, headache and/or malaise. Plasma 19 sodium levels below 100 mmol/L (2.3g/L) frequently result in cerebral edema, seizures, coma, and death within a few hours of drinking the excess water. As with alcohol poisoning, the progression from mild to severe symptoms may occur rapidly as the water continues to enter the body from the intestines or intravenously. The electrolyte disturbance hyponatremia or hyponatraemia exists in humans when the sodium level in the plasma falls below 135 mmol/l. ... Osmosis is the spontaneous net movement of water across a semipermeable membrane from a region of high solvent potential to an area of low solvent potential, up a solute concentration gradient. ... In some animals, including mammals, the two types of extracellular fluids are interstitial fluid and blood plasma. ... The cytosol (as opposed to cytoplasm, which also includes the organelles) is the internal fluid of the cell, and a large part of cell metabolism occurs here. ... This article or section does not adequately cite its references or sources. ... A diagram showing the CNS: 1. ... For other uses, see Brain (disambiguation). ... Cytolysis is the lysis, or death, of cells due to the rupture of the cell membrane. ... Look up cell membrane in Wiktionary, the free dictionary. ... Lightheadedness is a common and often unpleasant sensation of dizziness and/or feeling that one may be about to faint, which may be transient, recurrent, or occasionally chronic. ... For other uses, see Nausea (disambiguation). ... Emesis redirects here. ... A headache (cephalalgia in medical terminology) is a condition of pain in the head; sometimes neck or upper back pain may also be interpreted as a headache. ... Malaise is a feeling of general discomfort or uneasiness, an out of sorts feeling, often the first indication of an infection or other disease. ... Cerebral edema (cerebral oedema in British English) is an excess accumulation of water in the intra- and/or extracellular spaces of the brain. ... This article is about epileptic seizures. ... In medicine, a coma (from the Greek koma, meaning deep sleep) is a profound state of unconsciousness. ... For other uses, see Death (disambiguation). ... Alcohol poisoning is a serious — sometimes deadly — result of drinking excessive amounts of alcohol (ethanol). ...


A person with healthy kidneys can excrete about 900ml (0.24 gal)/hr.[2] However, this must be modulated by potential water losses via other routes. For example, a person who is perspiring heavily may lose 1 L/hr (0.26 gal) of water through perspiration alone, thereby raising the amount of water that must be consumed before the individual crosses the threshold for water intoxication. The problem is further complicated by the amount of electrolytes lost in urine or sweat, which is variable within a range controlled by the body's regulatory mechanisms. Kidneys viewed from behind with spine removed The kidneys are bean-shaped excretory organs in vertebrates. ...


Water intoxication can be prevented by consuming water that is isotonic with water losses, but the exact concentration of electrolytes required is difficult to determine and fluctuates over time. Over long periods of deficiencies between electrolyte loss and electrolyte intake, a small deficiency may reach the threshold is continued over many hours because of continual negative nett electrolyte intake. 70. ...


Sodium is not the only mineral that can become overdiluted from excessive water intake. Magnesium is also excreted in urine. According to the National Institutes of Health, "magnesium deficiency can cause metabolic changes that may contribute to heart attacks and strokes."[3] Intravenous magnesium is used in cardiac care units for cardiac arrhythmias.[4] General Name, symbol, number magnesium, Mg, 12 Chemical series alkaline earth metals Group, period, block 2, 3, s Appearance silvery white solid at room temp Standard atomic weight 24. ... National Institutes of Health Building 50 at NIH Clinical Center - Building 10 The National Institutes of Health (NIH) is an agency of the United States Department of Health and Human Services and is the primary agency of the United States government responsible for biomedical research. ... Santorio Santorio (1561-1636) in his steelyard balance, from Ars de statica medecina, first published 1614 Metabolism (from μεταβολισμος(metavallo), the Greek word for change), in the most general sense, is the ingestion and breakdown of complex compounds, coupled... Cardiac arrhythmia is any of a group of conditions in which the electrical activity of the heart is irregular or is faster or slower than normal. ...


High risk factors

Low body mass (infants)

It can be very easy for children under a year old to absorb too much water – especially if the child is under nine months old, because with their small body mass, it is easy to take in a large amount of water relative to body mass. It is also possible for a child to absorb too much water if submerged in it.[5]


Endurance sports

Marathon runners are susceptible to water intoxication if they drink only water while running. Although sweat is relatively hypotonic compared with body fluids, marathon runners perspire heavily for long periods, potentially causing their sodium levels to drop when they consume large amounts of fluids to quench their thirst. The replacement fluids may not contain sufficient sodium to replace what has been lost, and this puts them at high risk for water intoxication. Medical personnel at marathon events are trained to immediately suspect water intoxication when runners collapse or show signs of confusion. Properly designed electrolyte-replacement drinks and some sports drinks include electrolytes that make them roughly isotonic with sweat, which helps to prevent water intoxication. For other senses of this word, see Marathon (disambiguation). ... For other uses, see Running (disambiguation). ... This article does not cite any references or sources. ... A sports drink is a beverage which is supposed to rehydrate athletes, as well as restoring electrolytes, sugar, and other nutrients. ... An electrolyte is a substance which dissociates free ions when dissolved (or molten), to produce an electrically conductive medium. ...


Note that overconsumption of sodium (in drinks or also in food), as well as inadequate intake of water, can cause hypernatremia, a disorder that is nearly the opposite of water intoxication and equally dangerous. Improper use of salt tablets can cause hypernatremia also. Hypernatremia is an electrolyte disturbance consisting of an elevated sodium level in the blood (compare to hyponatremia, meaning a low sodium level). ...


Overexertion and heat stress

Any activity or situation that promotes heavy sweating can lead to water intoxication when water is consumed to replace lost fluids. Persons working in extreme heat and/or humidity for long periods must take care to drink and eat in ways that help to maintain electrolyte balance. Persons using drugs such as MDMA ("Ecstasy") may overexert themselves, perspire heavily, and then drink large amounts of water to rehydrate, leading to electrolyte imbalance and water intoxication (See the case of Leah Betts). Even people who are resting quietly in extreme heat or humidity may run the risk of water intoxication if they drink large amounts of water over short periods for rehydration. ecstasy and religious ecstasy MDMA, most commonly known today by the street name ecstasy, is a synthetic entactogen of the phenethylamine family whose primary effect is to stimulate the brain to rapidly secrete large amounts of serotonin, causing a general sense of openness, empathy, energy, euphoria, and well-being. ... A photograph of Leah Betts in a coma. ...


Psychiatric conditions

Psychogenic polydipsia is the psychiatric condition in which patients feel compelled to drink large quantities of water, thus putting them at risk of water intoxication. This condition can be especially dangerous if the patient also exhibits other psychiatric indications (as is often the case), as his or her care-takers might misinterpret the hyponatraemic symptoms. Psychogenic polydipsia is a special form of polydipsia, caused by mental disorders. ...


Specific disease

Diarrhea and vomiting can result in very large electrolyte losses, and although drinking water will replace lost water, the lost electrolytes may not be adequately replaced, which can result in water intoxication. Replacement fluids for vomiting and diarrhea should be properly balanced to make them isotonic with the fluids lost in these conditions. Special formulations exist for oral rehydration therapy in these cases. Types 5-7 on the Bristol Stool Chart are often associated with diarrhea Diarrhea (in American English) or diarrhoea (in British English) is a condition in which the sufferer has frequent watery, loose bowel movements (from the Greek word διάρροια; literally meaning through-flowing). Acute infectious diarrhea is a common cause... Emesis redirects here. ... Oral Rehydration Therapy, or ORT, is a simple, cheap, and effective treatment for diarrhea caused by, e. ...


A great many disorders can affect electrolyte balance, especially disorders of the kidneys. Diuretic therapy, mineralocorticoid deficiency, osmotic diuresis (as in the hyperglycemia of uncontrolled diabetes), and the multiple disorders associated with AIDS are other common causes of electrolyte imbalance, although they do not always produce water intoxication. Kidneys viewed from behind with spine removed The kidneys are bean-shaped excretory organs in vertebrates. ... This illustration shows where some types of diuretics act, and what they do. ... Diuresis is the production of urine by the kidney. ... Hyperglycemia or High Blood Sugar is a condition in which an excessive amount of glucose circulates in the blood plasma. ... This article is about the disease that features high blood sugar. ... For other uses, see AIDS (disambiguation). ...


Iatrogenic

When an unconscious person is being fed intravenously (for example, total parenteral nutrition or via a nasogastric tube) the fluids given must be carefully balanced in composition to match fluids and electrolytes lost. These fluids are typically hypertonic, and so water is often co-administered. If the electrolytes are not monitored (even in an ambulatory patient) either hypernatremia or hyponatremia may result. Total parenteral nutrition (TPN), is the practice of feeding a person intravenously, circumventing the gut. ... A nasogastric tube (NG tube) is a plastic tube, inserted into a nostril through the nose, into the throat, down the oesophagus and into the stomach. ... This article does not cite any references or sources. ... Hypernatremia is an electrolyte disturbance consisting of an elevated sodium level in the blood (compare to hyponatremia, meaning a low sodium level). ... The electrolyte disturbance hyponatremia or hyponatraemia exists in humans when the sodium level in the plasma falls below 135 mmol/l. ...


Some neurologic/psychiatric medications (Trileptal, among others) have been found to cause hyponatremia in some patients. Patients with diabetes insipidus are particularly vulnerable due to rapid fluid processing. Oxcarbazepine (Trileptal) is an anticonvulsant and mood stabilizing drug, used primarily in the treatment of epilepsy and bipolar disorder. ... The electrolyte disturbance hyponatremia or hyponatraemia exists in humans when the sodium level in the plasma falls below 135 mmol/l. ...


Treatment

Mild intoxication may remain asymptomatic and require only fluid restriction. In more severe cases, treatment consists of:

  • Diuretics to increase urination, which are most effective for excess blood volume
  • Saline given intravenously to restore sodium electrolyte levels
  • Vasopressin receptor antagonists

This illustration shows where some types of diuretics act, and what they do. ... In medicine, saline is a solution of sodium chloride (a substance also commonly known as table salt) in sterile water, used frequently for intravenous infusion, rinsing contact lenses, and nasal irrigation (or the yogic practice called jala neti). ... For sodium in the diet, see Edible salt. ... Arginine vasopressin (AVP), also known as argipressin or antidiuretic hormone (ADH), is a human hormone that is released when the body is low on water; it causes the kidneys to conserve water, but not salt, by concentrating the urine and reducing urine volume. ...

Prevention

Water intoxication can be prevented if a person's intake of water and electrolytes closely matches his or her losses. The body's regulatory mechanisms provide a very generous margin of safety if the two are imbalanced, but some extreme activities (such as heavy, prolonged physical exertion), as well as disease states, can overwhelm or impair these mechanisms. Avoid situations that provoke extreme or prolonged perspiration. Drinking fluids that are specially balanced to replace lost electrolytes can also help to prevent intoxication. Eating regularly can provide needed electrolytes if only normal water is available for rehydration.


Sports drinks are popular among athletes because they provide the necessary electrolytes to support extended exercise. They help keep the body balanced and carrying the right amount of fluids. However, not all drinks advertised as sports drinks are suitable for this purpose, and professional advice should be sought for potentially risky situations such as those described above. A sports drink is a beverage designed to help athletes rehydrate, as well as replenish electrolytes, sugar, and other nutrients, which can be depleted after strenuous training or competition. ... An electrolyte is a substance containing free ions that behaves as an electrically conductive medium. ...


Note that a person's innate sense of thirst is more sensitive to overall dehydration than to changes in electrolytes. Thus, it is possible to develop water intoxication while trying to satisfy thirst, if one drinks a great deal of water over a short period. A dangerous drop in electrolytes, such as the hyponatremia that leads to water intoxication, will not have any effect on thirst if one is sufficiently dehydrated. This article does not adequately cite its references or sources. ...


For people suffering from dehydration due to the heavy perspiration associated with heavy exertion or heat stress, drinking water to rehydrate is much more important than avoiding water intoxication, since the former is extremely common and the latter is rare. One should never avoid drinking water under such conditions; instead, other steps should be taken to ensure that electrolytes are replaced as well, as noted above. Dehydration (hypohydration) is the removal of water (hydro in ancient Greek) from an object. ...


Notable cases

is the 12th day of the year in the Gregorian calendar. ... Year 2007 (MMVII) is the current year, a common year starting on Monday of the Gregorian calendar and the AD/CE era in the 21st century. ... Jennifer Lea Strange was a 28-year-old woman who died of water intoxication on January 12, 2007 after taking part in a Sacramento, California, radio stations water-drinking contest. ... Coordinates: , Country State County Sacramento Incorporated July 1, 2003 Government  - Mayor David Sander  - Vice Mayor Linda Budge  - City Manager Ted A. Gaebler Area  - City  22. ... Nintendo Company, Limited (任天堂 or ニンテンドー Nintendō; NASDAQ: NTDOY, TYO: 7974 usually referred to as simply Nintendo, or Big N ) is a multinational corporation founded on September 23, 1889[1] in Kyoto, Japan by Fusajiro Yamauchi to produce handmade hanafuda cards. ... The Wii (pronounced as the pronoun we, IPA: ) is the fifth home video game console released by Nintendo. ... KDND is an FM station licensed to Sacramento, California at 107. ... A radio station is an audio (sound) broadcasting service, traditionally broadcast through the air as radio waves (a form of electromagnetic radiation) from a transmitter to an antenna and a thus to a receiving device. ... This article or section is in need of attention from an expert on the subject. ... FCC redirects here. ... A photograph of Leah Betts in a coma. ... ecstasy and religious ecstasy MDMA, most commonly known today by the street name ecstasy, is a synthetic entactogen of the phenethylamine family whose primary effect is to stimulate the brain to rapidly secrete large amounts of serotonin, causing a general sense of openness, empathy, energy, euphoria, and well-being. ... The terms fraternity and sorority (from the Latin words and , meaning brother and sister respectively) may be used to describe many social and charitable organizations, for example the Lions Club, Epsilon Sigma Alpha, Rotary International, Optimist International, or the Shriners. ... Hazing is an often ritualistic test and a task, which may constitute harassment, abuse or humiliation with requirements to perform random, often meaningless tasks, sometimes as a way of initiation into a social group. ... This article or section does not cite its references or sources. ... Delta Sigma Phi (ΔΣΦ, also known as DSPor Delta Sigsor Delt Sigs at Michigan State University) is a fraternity established at the City College of New York in 1899 and is a charter member of the North-American Interfraternity Conference. ... California State University, Chico is the second-oldest campus in the California State University system, and home to the Chico University Arboretum. ... Matthew Carrington (November 10, 1983-February 2, 2005), was a student at California State University, Chico, who was killed during a hazing incident at the Chi Tau fraternity house. ... Impact from a water drop causes an upward rebound jet surrounded by circular capillary waves. ... Female internees practicing calisthenics in Manzanar. ... A townhouse with basement windows showing A basement is one or more floors of a building that are either completely or partially below the ground floor. ... is the 33rd day of the year in the Gregorian calendar. ... Year 2005 (MMV) was a common year starting on Saturday (link displays full calendar) of the Gregorian calendar. ... is the 255th day of the year (256th in leap years) in the Gregorian calendar. ... This article is about the year. ... “The U.S. Air Force” redirects here. ... U.S. Army recruits learn about bayonet fighting skills in an infantry Basic Combat Training at Fort Benning, Georgia. ... This article does not cite any references or sources. ... Mens 20 km walk during the 2005 World Championships in Athletics in Helsinki, Finland. ... Craig Barrett (born 16 November 1971) is a New Zealand athlete specializing in long distance events. ... The 1998 XVI Commonwealth Games were held in Kuala Lumpur, Malaysia from September 11 to September 21 making it the first Asian country to act as host and the last Commonwealth Games for 20th Century. ... Andrew Warhola (August 6, 1928 — February 22, 1987), better known as Andy Warhol, was an American artist who became a central figure in the movement known as Pop art. ... Anna Wood was a schoolgirl from Sydney, Australia, who died at the age of 15 on October 24, 1995 at Royal North Shore Hospital, St. ... Also see: 2002 (number). ... The 100th running of the Boston Marathon, 1996 The Boston Marathon is an annual marathon sporting event hosted by the city of Boston, Massachusetts, on Patriots Day, the third Monday of April. ... For other uses, see Washington, D.C. (disambiguation). ...

See also

Water Portal

Image File history File links Drinking_water. ... An electrolyte is a substance containing free ions that behaves as an electrically conductive medium. ... The electrolyte disturbance hyponatremia or hyponatraemia exists in humans when the sodium level in the plasma falls below 135 mmol/l. ... Hypernatremia is an electrolyte disturbance consisting of an elevated sodium level in the blood (compare to hyponatremia, meaning a low sodium level). ... Oral Rehydration Therapy, or ORT, is a simple, cheap, and effective treatment for diarrhea caused by, e. ... Polydipsia is a medical condition in which the patient ingests abnormally large amounts of fluids by mouth. ... There are very few or no other articles that link to this one. ... KDND is an FM station licensed to Sacramento, California at 107. ...

References

  1. ^ Bird, Patrick J. (2000). You Can Drink Too Much Water. University of Florida. Retrieved on 2007-01-21.
  2. ^ Noakes, T.D.; G. Wilson, D.A. Gray, M.I. Lambert, S.C. Dennis (October 2001). Peak rates of diuresis in healthy humans during oral fluid overload. National Center for Biotechnology Information. Retrieved on 2007-01-21.
  3. ^ Facts about Dietary Supplements, Office of Dietary Supplements, National Institutes of Health, March 2001.
  4. ^ Jay S. Cohen, MD, Statin Drugs, 2005, page 129, ISBN 0-7570-0257-9.
  5. ^ Water Intoxication in Infants
  6. ^ Woman dies after water-drinking contest. MSNBC (January 13, 2007). Retrieved on 2007-05-10.
  7. ^ Hyponatremia ("Water Intoxication"). The DEA.org. Retrieved on 2007-05-10.
  8. ^ Lore, Mark (2005-02-10). Another death in the family. Chico news & review. Retrieved on 2007-05-10.
  9. ^ Grier, Peter. "Airman's Death Brings Training Changes", Aerospace World, Air Force Magazine Online, January, 2000. Retrieved on 2007-01-20. 
  10. ^ Reasons for dispensing with the holding of an inquest. Retrieved on 2007-05-10.
  11. ^ Doctors: Marathoner Died From Too Much Water (August 13, 2002). Retrieved on 2007-05-10.
  12. ^ District Officer Dies After Bike Ride: Over-Hydration Cited as Factor. Washington Post (August 11, 2005). Retrieved on 2007-05-10.

Year 2007 (MMVII) is the current year, a common year starting on Monday of the Gregorian calendar and the AD/CE era in the 21st century. ... is the 21st day of the year in the Gregorian calendar. ... Year 2007 (MMVII) is the current year, a common year starting on Monday of the Gregorian calendar and the AD/CE era in the 21st century. ... is the 21st day of the year in the Gregorian calendar. ... Lovastatin, the first statin to be marketed The statins (or HMG-CoA reductase inhibitors) form a class of hypolipidemic agents, used as pharmaceutical agents to lower cholesterol levels in people with or at risk for cardiovascular disease. ... For the news website, see MSNBC.com. ... January 13 is the 13th day of the year in the Gregorian calendar. ... Year 2007 (MMVII) is the current year, a common year starting on Monday of the Gregorian calendar and the AD/CE era in the 21st century. ... Year 2007 (MMVII) is the current year, a common year starting on Monday of the Gregorian calendar and the AD/CE era in the 21st century. ... is the 130th day of the year (131st in leap years) in the Gregorian calendar. ... Year 2007 (MMVII) is the current year, a common year starting on Monday of the Gregorian calendar and the AD/CE era in the 21st century. ... is the 130th day of the year (131st in leap years) in the Gregorian calendar. ... Year 2005 (MMV) was a common year starting on Saturday (link displays full calendar) of the Gregorian calendar. ... is the 41st day of the year in the Gregorian calendar. ... Year 2007 (MMVII) is the current year, a common year starting on Monday of the Gregorian calendar and the AD/CE era in the 21st century. ... is the 130th day of the year (131st in leap years) in the Gregorian calendar. ... Year 2007 (MMVII) is the current year, a common year starting on Monday of the Gregorian calendar and the AD/CE era in the 21st century. ... January 20 is the 20th day of the year in the Gregorian calendar. ... Year 2007 (MMVII) is the current year, a common year starting on Monday of the Gregorian calendar and the AD/CE era in the 21st century. ... is the 130th day of the year (131st in leap years) in the Gregorian calendar. ... is the 225th day of the year (226th in leap years) in the Gregorian calendar. ... Also see: 2002 (number). ... Year 2007 (MMVII) is the current year, a common year starting on Monday of the Gregorian calendar and the AD/CE era in the 21st century. ... is the 130th day of the year (131st in leap years) in the Gregorian calendar. ... ... is the 223rd day of the year (224th in leap years) in the Gregorian calendar. ... Year 2005 (MMV) was a common year starting on Saturday (link displays full calendar) of the Gregorian calendar. ... Year 2007 (MMVII) is the current year, a common year starting on Monday of the Gregorian calendar and the AD/CE era in the 21st century. ... is the 130th day of the year (131st in leap years) in the Gregorian calendar. ...

External links


  Results from FactBites:
 
Water - Wikipedia, the free encyclopedia (3386 words)
Water (in its pure form) is a tasteless, odorless substance that is essential to all known forms of life and is known also as the universal solvent.
In biological cells and organelles, water is in contact with membrane and protein surfaces that are hydrophilic, that is, surfaces that have a strong attraction to water.
Water is lost from the body in urine and feces, through sweating, and by exhalation of water vapor in the breath.
  More results at FactBites »


 

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