In 1924, Murphy bled dogs to make them anemic, and then fed them various substances, and gauged their improvement. He discovered that ingesting large amounts of liver had seemed to cure the disease. Minot and Whipple then set about to chemically isolate the curative substance and ultimately were able to isolate the vitamin B12 from the liver.
Born in Stoughton, Wis., Murphy was educated at the University of Oregon and Harvard Medical School.
Whipple on anemia in dogs, Murphy and Minot carried out a series of experiments on the influence of food in the treatment of pernicious anemia in human beings.
Murphy, Minot, and Whipple shared the 1934 Nobel Prize in physiology or medicine for “their discoveries concerning liver therapy in cases of anemia.”
William P. Murphy won the 1934 Nobel Prize for physiology or medicine for his role in the discovery of liver as the successful dietary treatment for pernicious anemia, a deadly disorder in which bone marrow ceases to produce the fully mature red blood cells needed to carry oxygen to all parts of the body.
Murphy's lifesaving contribution to society was further advanced by Harvard physician William Castle, who, in 1948, isolated the active ingredient in liver which promoted the development of fully mature red blood cells in patients suffering from pernicious anemia.
WilliamParryMurphy (Stoughton, Wisconsin, February 6, 1892 – October 9, 1987) was an American physician who shared the Nobel Prize in Physiology or Medicine in 1934 with George Richards Minot and George Hoyt Whipple for their combined work in devising and treating macrocytic anaemia.
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